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| 1 | Protective effect of ginger volatile oil against acetic acid-induced colitis in rats: a light microscopic evaluation显示文摘OBJECTIVE: Ulcerative colitis is a chronically recurrent infl ammatory bowel disease of unknown origin. In the present study, the effect of ginger(rhizome of Zing iber officinale Roscoe) volatile oil on a rat model of colitis was evaluated. METHODS: Volatile oil of ginger with doses of 100, 200, and 400 mg/kg, prednisolone(4 mg/kg), or vehicle were administered orally to groups of male Wistar rats(n = 6) for 5 d. Animals were randomly divided into 6 groups, each group consisting of 6 rats. Colitis was induced by intracolonic instillation of 2 mL of 4%(v/v) acetic acid solution. All rats were sacrificed 24 h later and the tissue injuries were assessed macroscopically and histopathologically. RESULTS: Ginger volatile oil with all doses reduced colon weight/length ratio(P < 0.01) and the effects were similar to the reference drugs. Higher oral doses of volatile oil(200 and 400 mg/kg) reduced ulcer severity(P < 0.05 and P < 0.01), ulcer area(P < 0.01) and ulcer index(P < 0.01). On the other hand, evaluation of microscopic scores showed that the dose of 400 mg/kg of volatile oil was effective to reduce infl ammation severity(P < 0.01) and infl ammation extent(P < 0.05) compared to the control group.CONCLUSION: It is concluded that ginger volatile oil could effectively reduce symptoms of experimental colitis in a dose-dependent manner. | Amir Rashidian Saeed Mehrzadi Ali Reza Ghannadi Parvin Mahzooni Samira Sadr Mohsen Minaiyan | 2014 | Journal of Integrative Medicine2014，12，2： | 7 |
| 2 | Role of menthol in treatment of candidial napkin dermatitis显示文摘 | Sabzghabaee A M Nili F Ghannadi A | 2011 | World J Pediatr2011，7，2： | 1 |
| 3 | Anti-inflamma- tory and wound healing activities of Aloe littoralis in rats 显示文摘 | Hajhashemi V Ghannadi A Heidari AH | 2012 | Res Pharm Sci2012，7，2： | 1 |
| 4 | Equilibrium, kinetic and thermodynamic study of the biusorption of uranium onto Cystoseria indica algae显示文摘 | Khani M H Keshtkar A R Ghannadi M | 2008 | Journal of Hazardous Materials2008，150，： | 1 |
| 5 | Equilibrium, kinetic and thermodynamic study of the biosorption of uranium onto cysto- seria indica algae显示文摘 | KHANI M H KESHTKAR A R GHANNADI M | 2008 | Journal of Hazardous Materials2008，150，： | 1 |
| 6 | Two-phase modeling of a gas phase fluidized bed reactor for the fluorination of uranium tetrafluoride显示文摘 | Khani M H Pahlavanzadeh H Ghannadi M | 2008 | Annals of Nuclear Energy2008，35，12： | 1 |
| 7 | Downregulation of IGF-Ⅰ R expression by RNAi inhibits proliferation and enhances chemosensitization of human colon cancer cells显示文摘 | Yavari K Taghikhani M Ghannadi Maragheh M | | 0，，01： | 1 |
| 8 | Formulation and an herbal antihemorrohid ointment from Quercus, Black cumin and Fenugreek for the treatment of internal anal hemorrhoids 显示文摘 | Aslani A Emami S Ghannadi physicochemical evaluation of A | 2009 | J Pharm Sci Tabriz Univ Med Sci2009，14，： | 1 |
| 9 | Kinetics study of the fluorination of uranium tetrafluoride in a fluidized bed reactor显示文摘 | Khani M H Pahlavanzadeh H Ghannadi M | 2008 | Annals of Nuclear Energy2008，35，4： | 1 |
| 10 | Fluorination of UF4 in a mini-tapered fluidized bed and mathematical modeling显示文摘 | Khani M H Ghannadi M Pahlavanzadeh H | 2010 | Annals of Nuclear Energy2010，37，9： | 1 |
| 11 | Downregu-lation of IGF-IR expression by RNAi inhibits proliferationand enhances chemosensitization of human colon cancercells显示文摘 | Yavari K Taghikhani M Ghannadi MM | 2010 | Int J Colorectal Dis2010，25，1： | 1 |
| 12 | Equilibrium, kinetic and thermodynamic study of the biosorption o显示文摘 | Khani M H Keshtkar A R Ghannadi M Pahlavanzadeh H | 2008 | Journal of Hazardous Materials2008，150，61： | 1 |
| 13 | The use of clinoptilolite and its sodium form for removal of radioactive cesium, and strontium from nuclear wastewater and Pb2+, Ni2+, Cd2+, Ba2+ from municipal wastewater显示文摘 | Faghihian H Ghannadi Marageh M Kazemian H | 1999 | Applied Radiation and Isotopes1999，50，： | 1 |
| 14 | Antinociceptive and anti-inflammatory effects of Satureja hortensis L . extracts and essential oil显示文摘 | Valiollah Hajhashemi Alireza Ghannadi Sayed Karim Pezeshkian | 2002 | Journal of Ethnopharmacology2002，，2： | 1 |
| 15 | Equilibrium, kinetic and thermodynamic study of the biosorption of uranium onto Cystoseria indica algae显示文摘 | KhaniMH KeshtkarAR Ghannadi M etal | 2008 | J HazardMater2008，150，3： | 1 |
| 16 | Comparative study of berberis vulgaris fruit extract and berberine chloride effects on acetic acid-induced colitis in rats 显示文摘 | Minaiyan M Ghannadi A Mahzouni P | 2011 | Iranian Journal of Pharmaceutical Research Ijpr2011，10，1： | 1 |
| 17 | Reproductive outcome following thawed embryo transfer in management of ovarian hyperstimulation syndrome显示文摘 | Absalan F Ghannadi A Kazerooni M | 2013 | J Reprod Infertil2013，14，3： | 1 |
| 18 | Reproductive outcome following thawed embryo transfer in management of ovarian hyperstimulation syndrome显示文摘 | Absalan F Ghannadi A Kazerooni M | 2013 | J Reprod Infertil2013，14，： | 1 |
| 19 | Sorption studies of radionuclides on a new ion exchanger: Cerium (III) silicate显示文摘 | M. Ghannadi Marageh S. Waqif Husain A.R. Khanchi S.J. Ahmady | 1996 | Applied Radiation and Isotopes1996，，5： | 1 |
| 20 | KineticsStudy of the Fluorination of Uranium Tetrafluoride in a Fluidized Bed Reactor显示文摘 | Khani M H Pahlavanzadeh H Ghannadi M | 2008 | Annals of Nuclear Energy2008，35，4： | 1 |
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