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| 1 | Differential diagnosis in inflammatory bowel disease colitis:State of the art and future perspectives显示文摘Distinction between Crohn's disease of the colonrectum and ulcerative colitis or inflammatory bowel disease(IBD) type unclassified can be of pivotal importance for a tailored clinical management,as each entity often involves specific therapeutic strategies and prognosis.Nonetheless,no gold standard is available and the uncertainty of diagnosis may frequently lead to misclassification or repeated examinations.Hence,we have performed a literature search to address the problem of differential diagnosis in IBD colitis,revised current and emerging diagnostic tools and refined disease classification strategies.Nowadays,the differential diagnosis is an untangled issue,and the proper diagnosis cannot be reached in up to 10% of patients presenting with IBD colitis.This topic is receiving emerging attention,as medical therapies,surgical approaches and leading prognostic outcomes require more and more disease-specific strategies in IBD patients.The optimization of standard diagnostic approaches based on clinical features,biomarkers,radiology,endoscopy and histopathology appears to provide only marginal benefits.Conversely,emerging diagnostic techniques in the field of gastrointestinal endoscopy,molecular pathology,genetics,epigenetics,metabolomics and proteomics have already shown promising results.Novel advanced endoscopic imaging techniques and biomarkers can shed new light for the differential diagnosis of IBD,better reflecting diverse disease behaviors based on specific pathogenic pathways. | Gian Eugenio Tontini Maurizio Vecchi Luca Pastorelli Markus F Neurath Helmut Neumann | 2015 | World Journal of Gastroenterology2015，21，1： | 13 |
| 2 | Optimization of room-and-pillar dimensions using automated numerical models显示文摘This paper presents an optimization methodology for the geometric configuration of a room–and–pillar mining project,considering safety and operational restrictions while maximizing ore recovery.An underground manganese mine was chosen as a case study to investigate the capabilities of the presented methodology.A software package(OPTIMINE)was implemented to address the computational demand in an automated manner.Three–dimensional finite difference analyses were performed in FLAC3D and used as implicit functions to consider safety in terms of the factor of safety and room convergence.The obtained results showed that recovery could be increased from 44%to more than 80%in a safe manner. | Gian Franco Napa-García Tais Renata Camara Vidal Félix Navarro Torres | 2019 | International Journal of Mining Science and Technology2019，29，5： | 2 |
| 3 | Pesticide in fluence on soilenzymatic activities显示文摘 | Sannino F Gian freda L | 2001 | Chemosphere2001，45，41： | 1 |
| 4 | Vehicle recognition and tracking from roads image sequences显示文摘 | GIAN L F VITTORIO M | 1999 | IEEE Trans Veh Tech1999，48，1： | 1 |
| 5 | Virtual Prototyping of Mechatronic System 显示文摘 | Gianni F Gian A M Paolo R | 2004 | Annual Review in Control (S1367-5788)2004，28，2： | 1 |
| 6 | Impact of exer-cise intensity and duration on insulin sensitivity in womenwith T2D显示文摘 | Segerstrom AB Gians F Eriksson KF | 2010 | Eur J Intern Med2010，21，40： | 1 |
| 7 | Various Notions of Chaos for Discrete Dynamical Systems, A Brief Survey 显示文摘 | GIAN L F | 2005 | Aequationes Mathematicae2005，70，： | 1 |
| 8 | Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension*显示文摘 | Hanspeter Brunner John R Cockcroft John Deanfield Ann Donald Ele Ferrannini Julian Halcox Wolfgang Kiowski Thomas F Lüscher Giuseppe Mancia Andrea Natali James J Oliver Achille C Pessina Damiano Rizzoni Gian Paolo Rossi Antonio Salvetti Lukas E Spieker St | 2005 | Journal of Hypertension2005，，2： | 1 |
| 9 | Spectroscopic methods for the analysis of celadonite and glauconite in Roman green wall paintings 显示文摘 | Ligia M Emilio F O Gian A M | 2011 | J Cult Herit2011，，12： | 1 |
| 10 | High performance liquid chromatographic determination of plasma free and total tazobactam and piperacillin显示文摘 | Gianna Di G Michele F Gian P | 2009 | J Chromatogr B2009，877，12： | 1 |
| 11 | Mechanisms of static and dynamic stereopsis in foveal cortex of the rhesus monkey 显示文摘 | Gian F P William H T | 1981 | J Physiol1981，315，： | 1 |
| 12 | Definition of a CFD Multi- phase Simulation Strategy to Allow a First Evaluation of the Cavitation Erosion Risk Inside High-Pressure Injector 显示文摘 | Federico B Stefania F Gian M B | 2015 | En- ergy Procedia2015，81，： | 1 |
| 13 | Virtual Prototyping of Mechatronic System显示文摘 | Gianni F Gian A M Paolo R | 2004 | Annual Review in Control2004，28，： | 1 |
| 14 | Virtual Prototyping of Mechatronic System显示文摘 | F Gianni A M Gian R Paolo | 2004 | Annual Review in Control2004，28，： | 1 |
| 15 | Free radical inte-rmediates in the inhibition of the autoxidation reaction显示文摘 | Marco L Gian F P | 2010 | Royal Society of Chemmistry2010，39，6： | 1 |
| 16 | The determinants of corporate entrepreneurial intention within small and newly estab- lished firms 显示文摘 | RICCARDO F ROSA G GIAN L M | 2012 | Entrepreneurial Theory and Practice2012，，3： | 1 |
| 17 | Testing the IMEter on rice introns and other aspects of intron-mediated enhancement of gene expression显示文摘 | Morello L Gianì S Troina F | | 0，，02： | 1 |
| 18 | Characterisation byXPS of the corrosion patina formed on bronze surfaces显示文摘 | Maria C Gian P Valentina F? | 2002 | Journal of Cultural Heritage2002，3，3： | 1 |
| 19 | Circular arc extraction by direct clustering in a 3D Hough parameter space显示文摘 | GIAN L F CARLO S R GIANNI V | 1995 | Signal Processing1995，41，2： | 1 |
| 20 | Guidelines for the management of spontaneous preterm labor: identification of spontaneous preterm labor, diagnosis of preterm premature rupture of membranes, and preventive tools forpretermbirth显示文摘 | Gian C D R Lluis C R Fabio F | 2011 | MaternFetalNeonatalMed2011，24，5： | 1 |
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