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| 1 | Free radical scavenger effect of rebamipide in sperm processing and cryopreservation显示文摘Alm:To study the effect of rebamipide added to semen samples and cryoprotectant on reactive oxygen species (ROS) production. Methods: Semen samples from 30 fertile and healthy volunteers were collected bymasturbation after 2 days-3 days of abstinence. After liquefaction, the specimens were diluted with sperm washmedia to a uniform density of 20×10^6/mL. Rebamipide was added to semen samples and cryoprotectant to a final concentration of 10μmol/L, 30μmol/L, 100μmol/L or 300μmol/L. Specimens were incubated at 37℃ in a 0.5 % CO2 incubator for I h or cryopreserved at -196℃ LN2 for 3 days. The sperm motility and viability and the levels of ROS and lipid peroxidation of sperm membrance were assessed before and after incubation and cryopreservation by means of computer assisted semen analyzer, eosin-nigrosin stain, chemiluminescence and thiobarbituric acid assay,respectively. Results: The sperm motility was significantly increased after incubation with 100 gmol/L and 300gmol/L rebamipide (P<0.05). After cryopreservation, the sperm motility was significantly decreased in all concentra-tions (P<0.05), but the decrease was less with 100μmol/L and 300μmol/L rebamipide than that with otherconcentrations. The sperm viability showed no significant difference before and after incubation (P>0.05). The levels of ROS and lipid peroxidation in semen were significantly decreased in proportion to the concentrations of rebamipide both after incubation and cryopreservation (P<0.05). Conclusion: Rebamipide is an effective flee radical scavenger in semen in vitro. ( Asian J Androl 2003 Sep; 5: 195-201) | Nam Cheol Park Hyun Jun Park Kyeong Mi Lee Dong Gil Shin | 2003 | Asian Journal of Andrology2003，5，3： | 4 |
| 2 | Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing 显示文摘 | Gil MI Tomrs-Barberrn FA Hess-Pierce B | 2000 | J Agric Food Chem2000，48，10： | 1 |
| 3 | Quality improvement of Pleurotus mushrooms by modified atmosphere packaging and moisture absorbers 显示文摘 | Villaeseusa R Gil MI | 2003 | Post- harvest Biology and Technology2003，28，1： | 1 |
| 4 | Dynamic arterial elastance to predict arterial pressure response to volume loading in pre- load-dependent patients显示文摘 | Monge Garcia MI Gil Cano A Gracia Romero M | 2011 | Crit Care2011，，： | 1 |
| 5 | Antioxidant activity of pomegranate juice and its relationship with phenolic composi- tion and processing 显示文摘 | Gil MI Tomas BFA Hess PB | 2000 | JAgri Food Chem2000，48，6： | 1 |
| 6 | CD24 + ovary cancer cells exhibit an invasive mesenchymal phenotype显示文摘 | Kyu Sub Kang Yoon Pyo Choi Ming-Qing Gao Suki Kang Baek Gil Kim Joo Hyun Lee Mi Jeong Kwon Young Kee Shin Nam Hoon Cho | 2013 | Biochemical and Biophysical Research Communications2013，，： | 1 |
| 7 | Brachial artery peak velocity variation to predict fluid responsiveness in mechanically ventilated patients显示文摘 | Monge Garcia MI Gil Cano A Diaz Monrove JC | 2009 | Crit Care2009，13，5： | 1 |
| 8 | Non- invasive assessment of fluid responsiveness by changes in partial end-tidal CO2 pressure during a passive leg-raising maneuver显示文摘 | Monge Garcia MI Gil Cano A Gracia Romero M | 2012 | Ann Intensive Care2012，2，： | 1 |
| 9 | Antioxidant activity of pomegranate juice and its relationship with phenolic composition and precessing显示文摘 | Tomas-Barberan FA Hess-Pierce B | 2000 | J Agric Food Chem2000，48，10： | 1 |
| 10 | In vitro availability of flavonoids and other phenolics in orange juice显示文摘 | Gil-Izquierdo A Gil MI Ferreres F | 2001 | Journal of Agricultural and Food Chemistry2001，49，2： | 1 |
| 11 | Respiratory and hemodynamic changes during lung recruitment maneuvering through progressive increases and decreases in PEEP level 显示文摘 | Monge Garc I a MI Gil Cano A Gracia Romero M | 2012 | Med Intensiva2012，36，2： | 1 |
| 12 | Quality improvement of Pleurotus mushrooms by modified atmosphere packaging and moisture absorbers 显示文摘 | VILLAESCUSA R GIL MI | 2003 | Postharvest Biol Tec2003，28，1： | 1 |
| 13 | Brachial artery peak velocity variation to predict fluid responsiveness in mechanically ventilated patients显示文摘 | Monge García MI Gil Cano A Díaz Monrové JC | | 0，，： | 1 |
| 14 | Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing显示文摘 | Gil MI Tomas-Barberan FA Hess-Pierce B | 2000 | J Agric Food Chem2000，48，： | 1 |
| 15 | Invasive giant prolactinoma with loss of therapeutic response to cabergoline : expression of angiogenic markers 显示文摘 | Mallea- Gil MS Cristina C Perez-Millan MI | 2009 | Endocr Pathol2009，20，1： | 1 |
| 16 | Non- invasive assessment of fluid responsiveness by changes in partial end-tidal C02 pressure during a passive leg-raising maneuver显示文摘 | Monge Gareta MI Gil Cano A Graeia Romero M | 2012 | Ann Intensive Care2012，2，： | 1 |
| 17 | HPLC-DAD-ESIMS analysis of phenolic compounds in nectarines,peaches,and plums显示文摘 | TOmS-Barberan FA Gil MI Cremin P | 2001 | Agricult Food Chemi2001，49，： | 1 |
| 18 | Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma显示文摘 | Sun Mi Hong Chang Wook Park Hyung Jin Cha Jung Hee Kwon Young Sung Yun Nam Gyu Lee Dae-Ghon Kim Hong Gil Nam Kwan Yong Choi | 2013 | Clinical & Experimental Metastasis2013，，2： | 1 |
| 19 | Quality improvement of Pleurotus mushrooms by modified atmosphere packaging and moisture absorbers显示文摘 | Villaescusa R Gil MI | 2003 | Postharvest Biology and Technology2003，28，1： | 1 |
| 20 | Browning susceptibility of minimally processed Baby and Romaine lettuces 显示文摘 | Castaner M Gil Mi Artes F | 1999 | Eur Food Technol1999，209，： | 1 |
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