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| 1 | Impact of Sea-Level-Rise and Human Activities in Coastal Regions:An Overview显示文摘Coastal regions are becoming increasingly vulnerable to flooding because of accelerating sea-level-rise(SLR),local ground subsidence,and the changes in topography and morphology.Moreover,coastal areas are usually highly urbanized and increased human activities have an effect on the stability and preservation of the environment.For instance,the growing demand for new lands to accommodate the population and the industrial facilities in China has required the design and the deployment of land-reclamation projects from the ocean,with a marked impact on fragile coastal eco-systems.Specifically,the Yangtze River and Pearl River Estuary,two major estuaries of the world,have long been subject to intensive human activities over the past decades.Long-term ground subsidence evolution,topographic changes,and morphological variation of the coastal regions have drawn great attention.This paper provides an overview of well-established Earth Observation(EO)remote sensing(RS)technologies that are employed to continuously monitor the changes of urbanized regions.The combined use of EO-based DInSAR analyses along with the knowledge of the geomorphology of the coastal regions allows a more precise picture of the SLR risk in the investigated coastal regions.In this paper,we will concentrate on remote sensing technologies that allow the gathering of heterogeneous information,such as those based on the use of synthetic aperture radar(SAR),satellite altimeters and tide gauge data.We will underline how human activities trigger changes in the living environment of coastal zones and the associated risks for the population.Observed coastline changes,coastal regions terrain subsidence,and offshore bathymetry have a pronounced effect on the increasing risk of flooding.Accordingly,we also present insights into some inundation model projections employed for evaluating the potential flooding risk in coastal regions. | Qing ZHAO Antonio PEPE Adam DEVLIN Shuangshang ZHANG Francesco FALABELLA Giovanni ZENI Qiang WANG Jingzhao DING Danan DONG Min LIU Qing XU Xia LEI Jiayi PAN | 2021 | Journal of Geodesy and Geoinformation Science2021,4,1: | 5 |
| 2 | Test-based exclusion diets in gastro-esophageal reflux disease patients:A randomized controlled pilot trial显示文摘AIM:To investigate the clinical response of gastroesophageal reflux disease(GERD)symptoms to exclusion diets based on food intolerance tests.METHODS:A double blind,randomized,controlled pilot trial was performed in 38 GERD patients partially or completely non-responders to proton pump inhibitors(PPI)treatment.Fasting blood samples from each patients were obtained;leukocytotoxic test was performed by incubating the blood with a panel of 60food items to be tested.The reaction of leukocytes(rounding,vacuolization,lack of movement,flattening,fragmentation or disintegration of cell wall)was then evaluated by optical microscopy and rated as follows:level 0=negative,level 1=slightly positive,level 2=moderately positive,and level 3=highly positive.A'true'diet excluding food items inducing moderatesevere reactions,and a'control'diet including them was developed for each patient.Then,twenty patients received the'true'diet and 18 the'control'diet;after one month(T1)symptoms severity was scored by the GERD impact scale(GIS).Hence,patients in the'control'group were switched to the'true'diet,and symptom severity was re-assessed after three months(T2).RESULTS:At baseline(T0)the mean GIS global score was 6.68(range:5-12)with no difference between'true'and control group(6.6±1.19 vs 6.7±1.7).All patients reacted moderately/severely to at least 1 food(range:5-19),with a significantly greater number of food substances inducing reaction in controls compared with the'true'diet group(11.6 vs 7.0,P<0.001).Food items more frequently involved were milk,lettuce,brewer’s yeast,pork,coffee,rice,sole asparagus,and tuna,followed by eggs,tomato,grain,shrimps,and chemical yeast.At T1 both groups displayed a reduction of GIS score('true'group 3.3±1.7,-50%,P=0.001;control group 4.9±2.8,-26.9%,P=0.02),although the GIS score was significantly lower in'true'vs'control'group(P=0.04).At T2,after the diet switch,the'control'group showed a further reduction in GIS score(2.7±1.9,-44.9%,P=0.01),while the'true'group did not(2.6±1.8,-21.3%,P=0.19),so that the GIS scores didn’t differ between the two groups.CONCLUSION:Our results suggest that food intolerance may play a role in GERD symptoms development,and leucocytotoxic test-based exclusion diets may be a possible therapeutic approach when PPI are not effective or indicated. | Michele Caselli Giovanni Zuliani Francesca Cassol Nadia Fusetti Elena Zeni Natalina Lo Cascio Cecilia Soavi Sergio Gullini | 2014 | World Journal of Gastroenterology2014,20,45: | 1 |
| 3 | An Overview of the Small BAseline Subset Algorithm: a DInSAR Technique for Surface Deformation Analysis显示文摘 | Riccardo Lanari Francesco Casu Mariarosaria Manzo Giovanni Zeni Paolo Berardino Michele Manunta Antonio Pepe | 2007 | Pure and Applied Geophysics2007,,4: | 1 |
| 4 | Biochemical sensing exploiting plasmonic sensors based on gold nanogratings and polymer optical fibers显示文摘In this work,we present a novel biochemical sensing approach based on a plasmonic sensor chip,combined with a specific receptor,excited and interrogated via a custom 3D-printed holder through a transmission-based experimental setup,exploiting polymer optical fibers. The setup is designed to measure a disposable plasmonic chip based on a gold nanograting fabricated on a polymethylmethacrylate substrate. The examined sensor configurations here presented are simulated,realized,and experimentally tested. More specifically,first,a numerical analysis is carried out by changing several sensor parameters,then an experimental optical characterization of different sensor configurations is reported. Finally,to test the biosensing capabilities of the proposed method,as a proof of concept,we deposit on the best sensor configuration a biomimetic receptor specific for bovine serum albumin detection. The experimental results demonstrate that the proposed sensor shows an ultra-low limit of detection,equal to about 37 pmol/L. | FRANCESCO ARCADIO LUIGI ZENI DOMENICO MONTEMURRO CATERINA ERAMO STEFANIA DI RONZA CHIARA PERRI GIROLAMO D’AGOSTINO GUIDO CHIARETTI GIOVANNI PORTO NUNZIO CENNAMO | 2021 | Photonics Research2021,9,7: | 0 |