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23篇 您的检索式:作者名="Gizis"
    题名 作者 年代 出处 被引量
1Predictors of response to anti-tumor necrosis factor therapy in ulcerative colitis显示文摘Ulcerative colitis(UC) is an immune-mediated, chronic inflammatory disease of the large intestine. Its course is characterized by flares of acute inflammation and periods of low-grade chronic inflammatory activity or remission. Monoclonal antibodies against tumor necrosis factor(anti-TNF) are part of the therapeutic armamentarium and are used in cases of moderate to severe UC that is refractory to conventional treatment with corticosteroids and/or immunosuppressants. Therapeutic response to these agents is not uniform and a large percentage of patients either fail to improve(primary non-response) or lose response after a period of improvement(secondary non-response/loss of response). In addition, the use of anti-TNF agents has been related to uncommon but potentially serious adverse effects that preclude their administration or lead to their discontinuation. Finally, use of these medications is associated with a considerable cost for the health system. The identification of parameters thatmay predict response to anti-TNF drugs in UC would help to better select for patients with a high probability to respond and minimize risk and costs for those who will not respond. Analysis of the major clinical trials and the accumulated experience with the use of anti-TNF drugs in UC has resulted to the report of such prognostic factors. Included are clinical and epidemiological characteristics, laboratory markers, endoscopic indicators and molecular(immunological/genetic) signatures. Such predictive parameters of long-term outcomes may either be present at the commencement of treatment or determined during the early period of therapy. Validation of these prognostic markers in large cohorts of patients with variable characteristics will facilitate their introduction into clinical practice and the best selection of UC patients who will benefit from anti-TNF therapy.Evanthia Zampeli Michalis Gizis Spyros I Siakavellas Giorgos Bamias 2014World Journal of Gastrointestinal Pathophysiology2014,5,3:2
2Differential expression of the TL1A/DcR3 system of TNF/TNFR-like proteins in large vs. small intestinal Crohn’s disease显示文摘Giorgos Bamias Garyfallia Kaltsa Spyros I. Siakavellas Michalis Gizis George Margantinis Evanthia Zampeli Irene Vafiadis-Zoumboulis Spyros Michopoulos George L. Daikos Spiros D. Ladas 2011Digestive and Liver Disease2011,,1:1
3Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler system显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,:1
4Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler system显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
5Real time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler system显示文摘StathopoulouA Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
6Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lighteycler system显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,:1
7A Novel De- sign of High-Sensitive Fuzzy PID Controller显示文摘A1 Gizi A J H Mustafa M W Jebur H H 2014Applied Soft Computing2014,24,:1
8As- sessment of oxidative stress in patients with sickle cell dis-ease :The glutathione system and the oxidant-antioxidant sta- tus 显示文摘GIZI A PAPASSOTIRIOU I APOSTOLAKOU F 2011Blood Cells Mol Dis2011,46,3:1
9Integrated PLC-fuzzy PID simulink implemented AVR system 显示文摘GIZI A J H A MUSTAFA M W ZAIDI K M A A 2015International Journal of Electrical Power & Energy Systems2015,69,:1
10Beliefs,Attitudes ,and Resource Use of High School Wrestling Coaches显示文摘SOSSIN K GIZIS F MARQUART L F 1997Int J Sport Nutr1997,7,3:1
11The Role of Vitamin D Receptor in Innate and Adaptive Immunity: A Study in Hereditary Vitamin D-Resistant Rickets Patients 显示文摘Dov Tiosano Gizi Wildbaum Vardit Gepstein 2013J Clin Endo- erinol Metab2013,98,4:1
12Real - time quantification of CK - 19 mRNA- positive cells in peripheral blood of breast cancer patients using the lightcycler system显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
13Real-time quan- tification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler sys- tem 显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
14Plasmid DNA Encoding IFN-γ-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis显示文摘Gizi W Nir N Nathan K 2002J Immunol2002,168,:1
15A novel design of highsensitive fuzzy PID controller显示文摘Gizi A J H A Mustafa M W Jebur H H 2014Applied Soft Computing2014,24,:1
16Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler system显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
17Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast can- cer patients using the ligbtcycler system 显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
18RealTime Quantification of CK-19 mRNA-Positive Cells in Peripheral Blood of Breast Cancer Patients Using the Lightcycler System显示文摘Aliki Stathopoulou Anna Gizi Maria Perraki 2003Clinical Cancer Research2003,9,1:1
19Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer pa-tients using the lightcycler system显示文摘Stathopoulou A Gizi A Perraki M 2003Clin Cancer Res2003,9,14:1
20Real-Time Quantification of CK-19 mRNA-Positive Ceils in Peripheral Blood of Breast Cancer Patients Using the Lightcycler System显示文摘Aliki Stathopoulou Anna Gizi Maria Perraki 2003Clini- cal Cancer Research2003,9,:1
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