|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Science behind cisplatin-induced nephrotoxicity in humans:A clinical study显示文摘Objective:To investigate the relationship between serum electrolyte changes and cisplatin induced nephrotoxicity.Methods:We collected data from 18 patients undergoing cisplatin chemotherapy including serum electrolytes,creatinine,blood urea nitrogen(BUN) and urine potassium,sodium and pH levels before and after the cisplatin chemotherapy.All the patients had cancer and were treated with 40-50 mg/day cisplatin.Renal injury was assessed by measuring serum electrolytes,creatinine,BUN levels and urine potassium,sodium and pH levels. Results:The five cycles of cisplatin based chemotherapy resulted in hypomagnesia(P=0.029), hypocalcaemia(P=0.001~*),hypophosphatemia(P=0.003*),hypokalemia(P=0.001~*)and increased serum creatinine(P=0.001~*)and BUN(P=0.292~*)levels.In urine analysis,decrease in potassium(P=0.024~*)was found,except potassium there was no significant changes in sodium and urine pH. Conclusions:The present study demonstrates that,acute nephrotoxicity was observed in patients with different types of cancers undergoing cisplatin based chemotherapy due to electrolyte disturbances,when no corrective measures were initiated. | Arunkumar PA Viswanatha GL Radheshyam N Mukund H Belliyappa MS | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，8： | 3 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity显示文摘 | Cheng Q Aleksunes LM Manautou JE Cherrington NJ Scheffer GL Yamasaki H | 2008 | Mol Pharm2008，5，1： | 1 |
| 4 | Cancer cell heparanase activity assiociated with invasion and metastasis显示文摘 | Nicolson GL Nakajima M Wakabayashi H | 1998 | Adv Enzyme Regul1998，38，： | 1 |
| 5 | Stereotactic radiosurgery as primary and salvage treatment for brain metastases from breast cancer 显示文摘 | Kondziolka D Kano H Harrison GL | 2011 | J Neurosurg2011，114，3： | 1 |
| 6 | Adult neurogenesis in the mammalian central nervous system显示文摘 | Ming GL Song H | 2005 | Annu Rev Neurosci2005，28，： | 1 |
| 7 | Effects of polarity andpHon the solubility of acid-treated carbon nanotubes in different media显示文摘 | Shieh YT Liu GL Wu H H etal | 2007 | Carbon2007，45，9： | 1 |
| 8 | p21-containing cyclin kinase exist in both active and inactive states 显示文摘 | Zhang H Hannon GL Beach D | 1994 | Genes Dev1994，8，15： | 1 |
| 9 | Identification of hypoxia inducible factor-1α protein in common human cancers显示文摘 | Zhong H DeMarzo AM Semenza GL | 1999 | Proc Am Ass Cancer Res1999，40，3： | 1 |
| 10 | Raf kinase inhibitor protein correlates with sensitivity of nasopharyngeal carcinoma to radiotherapy 显示文摘 | Ruan L Wang GL Yi H | 2010 | J Cell Bioehem2010，110，： | 1 |
| 11 | Newborn screening for congenital ad- renal hyperplasia has reduced sensitivity in girls 显示文摘 | Varness Ts Allen Db Gl H | 2005 | J Pediatr2005，147，4： | 1 |
| 12 | The role of protein kinase C activation in diabetic nephropathy 显示文摘 | Noh H King GL | 2007 | Kidney Int Suppl2007，，106： | 1 |
| 13 | Distribution of adsorbed antigen in mono-valent and combination vaccines 显示文摘 | Morefield GL HogenEseh H Robinson JP | 2004 | Vaccine2004，，1516： | 1 |
| 14 | Blood pressure, hypertension, RAAS blockade, and drug therapy in diabetic kidney disease显示文摘 | Yamout H Lazich I Bakris GL | 2014 | Adv Chronic Kidney Dis2014，21，3： | 1 |
| 15 | Inhibition of glucocorticoid-induced alter- ation of vimentin by a glucocorticoid receptor antagonist RU486 in the organ-cultured rat len 显示文摘 | Xie GL Yan H Lu ZF | 2011 | Mol Vis2011，17，： | 1 |
| 16 | A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability 显示文摘 | AMIDON GL LENNERNAS H SHAH VP | 1995 | Pharm Res1995，12，3： | 1 |
| 17 | Hardiness,work sup- port and psychological distress among nursing assistants and reg- istered nurses in Quebec显示文摘 | Madelaine H Gamen GL Andre Dyetal | 2007 | J Adv Nurs2007，38，6： | 1 |
| 18 | Effects of adding fenofibrate(2 00mg/d) in patient with combined hyperlipidemia and metabolic syndrome显示文摘 | Vega GL Duez H Blanquart C | 2003 | Am J Cardiol2003，91，： | 1 |
| 19 | Adult neurogenesis in the mammalian central nervous system显示文摘 | Ming GL Song H | | 0，，： | 1 |
| 20 | A theoretical basis for a biophannaceutie drug classification: the correlation of in vitro drug product dissolution and in varo bioavailabilit 显示文摘 | Amidon GL Lennern H Shah VP | 1995 | Pharm Res1995，12，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员