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12篇 您的检索式：作者名="Glyn R"

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		题名	作者	年代	出处	被引量
	1	Methylation of TIMP3 in esophageal squamous cell carcinoma显示文摘AIM: To measure the frequency of DNA methylation of the tissue inhibitor of metalloproteinase 3 (TIMP3) promoter and relate this to any change of gene expression in esophageal squamous cell carcinoma in patients from a region of high incidence in China.METHODS: Cancer cell lines were treated with or without the demethylating reagent 5-aza-2’-deoxycytidine. Methylation of the TIMP3 promoter was assessed in three regions by melt curve analysis and its expression was assessed by real-time RT-PCR. Tumors and proximal resection margins were obtained from 64 patients with esophageal squamous cell carcinoma from a region of high incidence in China. Methylation was assessed by melt curve analysis and expression by immunohistochemistry.RESULTS: Methylation in one of the three promoter regions assessed correlated with gene silencing in esophageal cell lines. A degree of methylation of TIMP3 was found in only four esophageal squamous cell carcinomas, and partial loss of TIMP3 protein expression in just one.CONCLUSION: Methylation and loss of expression of TIMP3 occurs infrequently in esophageal squamous cell carcinoma in a region of high incidence in China.	Eric Smith Neville J De Young Zi-Qiang Tian Maria Caruso Andrew R Ruszkiewicz Jun-Feng Liu Glyn G Jamieson Paul A Drew	2008	World Journal of Gastroenterology2008，14，2：	2
	2	New insights from comprehensive on-road measurements of NOx , NO2 and NH3 from vehicle emission remote sensing in London, UK 显示文摘	DAVID C C GLYN R T	2013	Atmospheric Environment2013，81，：	1
	3	Evaluation of variable number tandem repeat(VNTR)loci in molecular of Mycobacterium bovis isolates from Ireland显示文摘	Roring S Scott A N Glyn Hewinson R	2004	Vet Microbiol2004，101，：	1
	4	Osteo- arthritis显示文摘	GLYN J S PALMER A J AGRICOLA R	2015	Lancet2015，386，9991：	1
	5	Central administration of peptides alters thermoregulation in the rabbit显示文摘	Lipton J M Glyn J R	1980	Peptides1980，1，：	1
	6	Osteoarthritis 显示文摘	Glyn - Jones S Palmer AJ Agricola R	2015	Lancet2015，386，9991：	1
	7	The copper active site of CBM33 polysaceharide oxygenases 显示文摘	Glyn R Edward J Robbert Q	2013	Journal of the American Chemical Society2013，135，16：	1
	8	Modified and conventional ultrafiltration during pediatric cardiac surgery:clinical outcomes compared显示文摘	Glyn D Williams Chandra R Larry C	2006	J Thorac Cardiovasc Surg2006，132，11：	1
	9	A Method for the Design of Optimal Transport Strategies显示文摘	Zhang X Paulley N Hudson M Glyn R	2006	Transport Policy2006，13，4：	1
	10	Modified and conventional ultrafiltration during pediatric cardiac surgery : Clinical outcomes compared 显示文摘	Glyn DW Chandra R Larry C	2006	J Thorac Cardiovasc Surg2006，132，11：	1
	11	The effects of pharmaceutical excipients on drug disposition显示文摘	Talia R Paul A Glyn Taylor	2007	Adv Drug Deliv Rev2007，59，：	1
	12	Evaluation of variable number tandem repeat(VNTR) loci in molecular typ- ing of Mycobacterium boris isolates from Ireland显示文摘	Roring S Scott AN Glyn Hewinson R	2004	Vet Micro-biol2004，，：	1

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