维普期刊资源整合服务平台（V6.5）

85篇 您的检索式：作者名="Gmeiner"

选中清除导出查看参考文献查看引证文献引用追踪共5页首页上一页第1页下一页末页 /5 跳转

	题名	作者	年代	出处	被引量
1	Binding pathway determines norepinephrine selectivity for the human β_(1)AR over β_(2)AR显示文摘Beta adrenergic receptors(βARs)mediate physiologic responses to the catecholamines epinephrine and norepinephrine released by the sympathetic nervous system.While the hormone epinephrine binds β_(1)AR and β_(2)AR with similar affinity,the smaller neurotransmitter norepinephrine is approximately tenfold selective for the β_(1)AR.To understand the structural basis for this physiologically important selectivity,we solved the crystal structures of the human β_(1)AR bound to an antagonist carazolol and different agonists including norepinephrine,epinephrine and BI-167107.Structural comparison revealed that the catecholamine-binding pockets are identical between β_(1)AR and β_(2)AR,but the extracellular vestibules have different shapes and electrostatic properties.Metadynamics simulations and mutagenesis studies revealed that these differences influence the path norepinephrine takes to the orthosteric pocket and contribute to the different association rates and thus different affinities.	Xinyu Xu Jonas Kaindl Mary J.Clark Harald Hübner Kunio Hirata Roger K.Sunahara Peter Gmeiner Brian K.Kobilka Xiangyu Liu	2021	Cell Research2021，31，5：	2
2	Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments and computational studies of novel dopamine agonists recognizing preferentially the d3 subtype显示文摘	Hübner H Gmeiner P Utz W	2000	J Med Chem2000，43，4：	1
3	An efficient synthesis of[8-13C]adenine显示文摘	Gmeiner WH Poulter CD		0，，06：	1
4	Determination of seventeen polycyclic aromatic hydrocarbons in tobacco smoke condensate显示文摘	Gmeiner G Stehlik G Tausch H	1997	J chromatogr A1997，767，：	1
5	Apollon/RNF41myocardial messenger RNA diagnoses cardiac allograft apoptosis in rejection显示文摘	Aharinejad S Andrukhova O Gmeiner M	2010	Transplantation2010，89，2：	1
6	Characterisation of intact recombinant human erythropoietins applied in doping by means of planar gel electrophoretic techniques and matrix - assisted laser desorption/ionisation linear time - of - flight mass spectrometry显示文摘	Gerald Sttibiger Martina Marchetti Marietta Nagano Christian Reichel ( tinter Gmeiner Gtinter Allmaier	2005	Rapid Communications in Mass Spectrometry2005，19，5：	1
7	Fast screening method for the profile analysis of polycyclic aromatic hydrocarbon metabolites in urine using derivatisation-solid-phase microextraction 显示文摘	Gmeiner G Krassnig C Schmid E	1998	Chromatogr Biomed Sci Appl1998，705，1：	1
8	2-Dibenzylaminobutane-1 ,4-diol : a versatile intermediate for a ehirospeeific β-amino acid synthesis 显示文摘	Peter Gmeiner	1995	Tetrahedron Letters1995，36，3：	1
9	Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor显示文摘	Goetz A Lanig H Gmeiner P Clark T		0，，04：	1
10	Investigation into the electrochemical reduction ofdyestuffs 显示文摘	BECHTOLD T BURTSCHER E GMEINER D	1991	Melliand Textilberichte - InternationalTextile Reports1991，72，1：	1
11	Determination of seventeen polycyclic aromatic hydrocarbons in tobacco smoke condensate显示文摘	GMEINER G STEHLIK G TAUSCH H	1997	J Chromatogr A1997，，767：	1
12	Fast screening method for the profile analysis of polycyclic aromatic hydrocarbon metabolites in urine using derivatisation solid-phase microextraction 显示文摘	Gmeiner G Krassing C Schmid E	1998	J Chromatogy B1998，705，：	1
13	Infuence of a synbiotic mixture consisting of Lactobacillus acidophilus 74-2 and a fructooligosaccharide preparation on the microbial ecology sustained in a simulation of the human intestinal microbial ecosystem显示文摘	Gmeiner M Kneigel W Kulbe K D	2000	Appl Microbiol Biotechnol2000，53，：	1
14	49A/G and CT60 polymorphisms of the cytotoxic T-lymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease显示文摘	Ajda Bicek Katja Zaletel Simona Gaberscek Edvard Pirnat Blaz Krhin Tanja Gmeiner Stopar Sergej Hojker	2009	Human Immunology2009，，10：	1
15	Determination of seventeen polycyclic aromatic hydrocarbons in tobacco smoke condensate显示文摘	GMEINER G STEHLIK G TAUSCH H	1997	J Chromatogr A1997，767，：	1
16	Cylic amidines as benzamide bioisosteres:EPC synthesis and SAR studies leading to the selective D4 receptor agonist FAUC 312显示文摘	Jürgen Einsiedel Harald Hübner Peter Gmeiner	2003	Bioorganic & Medicinal Chemistry Letters2003，13，：	1
17	The structural evolution of dopamine D3 receptor ligands: Structure - activity relationships and selected neuropharmacologieal aspects 显示文摘	Frank Boeckler Peter Gmeiner	2006	Pharmacology & Therapeutics2006，112，：	1
18	Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMPwith fluorouracil, floxuridine, andtopoisomerase 1 poisons显示文摘	Gmeiner WH Reinhold WC Pommier Y	2010	Mol Cancer Ther2010，9，12：	1
19	Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris显示文摘	Krainer F W Gmeiner C Neutsch L	2013	Sci Rep2013，3，：	1
20	The structural evolution of dopamine D3 receptor ligands: Structure - activity relationships and selected neuropharmacological aspects 显示文摘	Frank Boeckler Peter Gmeiner	2006	Pharmacology & Therapeutics2006，112，1：	1

返回顶部每页显示：

共5页首页上一页第1页下一页末页 /5 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示