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| 1 | 2004年加拿大预防血透病人医院血流感染的成本-效益分析显示文摘目的:血液透析相关的血流感染是一个严重的公共健康问题,因为加拿大的血液透析病人从1996年到2005翻了一番。本研究目的在于确定加拿大医院血流感染的成本,估算在综合性医院中建立感染控制项目的成本,并进行成本-效益分析。材料与方法:用加拿大医院感染监测项目的数据来估算医院血流感染的发生率。用加拿大健康信息所数据来估算2004年加拿大平均一次血流感染住院的额外成本。建立和维护一个感染控制项目的成本用美国疾病预防与控制中心1985年的成本换算为2004年的加拿大成本来估算。假设感染控制项目能降低医院血流感染病例的20%~30%。结果:2004年的加拿大15278名血液透析病人中估计共有2524人发生血流感染。全年用于治疗血流感染的成本估计为4901万加元。医院血流感染预防和人力资源的总投资成本为815万加元。建立医院感染控制项目后能带来1452万加元的医疗成本节约。效益成本比在1.0:1到1.8:1之间。结论:本研究提供的证据表明,如果医院感染控制项目能降低20%~30%的感染,该项目的经济效益将远超过增加的成本。医院感染控制项目将带来双重效益:节约货币成本的同时改善医疗质量。 | Zhiyong Hong MD DrPH Jun Wu PhD Crystal O'Leary BHSc Clem Tisdell James Gomes Shi-Wu Wen Howard Njoo 李洪超 | 2010 | 中国药物经济学2010，，1： | 2 |
| 2 | Atrogin-1,a muscle-specific F-box protein highly expressed during muscle atrophy显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | Proc Natl Acad Sci USA2001，98，14： | 1 |
| 3 | Steroid estrogen de- termination in sediment and sewage sludge:a critique of sample preparation and chromatographic/mass spectrometry considera- tions,ineorporationg a case study in method development 显示文摘 | Gomes RL Aveioglu E Scrimshaw MD | 2004 | Trends Anal Chem2004，23，1011： | 1 |
| 4 | Phytochemical characterization and antinociceptive effect ofLippia gracilis Schauer显示文摘 | Guimares AG Gomes SV Moraes VR Nogueira PC Ferreira AG Blank AF Santos AD Viana MD Silva GH Quintans Júnior LJ | 2012 | J Nat Med2012，66，3： | 1 |
| 5 | Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | Proc Natl Acad Sci U S A2001，98，14： | 1 |
| 6 | Systemic effects of nocturnal hypoxemia in patients with chronic obstructive pulmonary disease without obstructive sleep apnea syndrome显示文摘 | Mueller PdTG Gomes MD Viegas CAdA | 2008 | J Bras Pneumol2008，34，8： | 1 |
| 7 | Neutralizing anti- bodies to enterovirus 71 in Bel6m, Brazil 显示文摘 | Gomes MD de Castro CM Oliveira MJ | 2002 | Mere Inst Oswaldo Cruz2002，97，1： | 1 |
| 8 | Atrogin - 1, a muscle - specificF- box protein highly expressed during muscle atrophy 显示文摘 | Gomes MD Lecker SI-l Jagoe RT | 2001 | Proc Natl Acad Sci USA2001，98，14： | 1 |
| 9 | Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy 显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | Proc Natl Acad Sci USA2001，98，14： | 1 |
| 10 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | David N Juurlink MD PhD Tara Gomes MHSc | 2009 | CMAJ2009，80，7： | 1 |
| 11 | Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy 显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | Proc Natl Acad Sci U S A2001，98，14： | 1 |
| 12 | Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy 显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | Proc Natl Acad Sci U S A2001，98，14： | 1 |
| 13 | Community acquired pneumonia among pediatric outpatient in Salvador, Northeast Brazil,with Emphasis on the role of pneumococcus 显示文摘 | Nascimento - Carvalho CM Lopes AA Gomes MD | 2001 | Braz J Infect Dis2001，5，1： | 1 |
| 14 | Atrogin-1,a muscle-specific F-box protein highly expressed during muscle atrophy显示文摘 | Gomes MD Lecker SH | | 0，，25： | 1 |
| 15 | Atrogin-1, a musclespecific F-box protein highly expressed during muscle atrophy 显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | Proc Natl Acad Sci USA2001，98，14： | 1 |
| 16 | Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation显示文摘 | Gomes B Cabral MD Gallard A | | 0，，： | 1 |
| 17 | Controlled ovarian stimulation with exclusive FSH followed by stimulation with hCG alone, FSH alone or hMG 显示文摘 | Gomes MK Vieira CS Moura MD | 2007 | Eur J Obstet Gynecol Reprod Biol2007，130，1： | 1 |
| 18 | Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation显示文摘 | Gomes B Cabral MD Gallard A | | 0，，： | 1 |
| 19 | Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy 显示文摘 | Gomes MD Lecker SH Jagoe RT | 2001 | PNAS2001，98，14： | 1 |
| 20 | Controlled ovarian stimulation with exclusive FSH followed by stimulation with hCG alone,FSH alone or hMG显示文摘 | Gomes MK Vieira CS Moura MD | 2007 | Eur J Obstet Gynecol Reprod Biol2007，130，1： | 1 |
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