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| 1 | Risk-adjustment in hepatobiliarypancreatic surgery显示文摘AIM: The present study evaluates the performance of the POSSUM, the American Society of Anesthetists (ASA),APACHE and Childs classification in predicting mortality and morbidity in hepatopancreaticobiliary (HPB) surgery.We describe especially the limitations and advantages of risk in stratifying the patients.METHODS: We investigated 177 randomly chosen patients undergoing eledive complex HPB surgery in a single institution with a total of 71 pre-operative and intra-operative risk factors.Primary endpoint was in-hospital mortality and morbidity.Ordered logistic regression analysis was used to identify individual predictors of operative morbidity and mortality.RESULTS: The operative mortality in the series was 3.95% .This compared well with the p-POSSUM and APACHE predicted mortality of 4.31% and 4.29% respectively. Postoperative complications amounted to 45% with 24 (13.6%)patients having a major adverse event. On multivariate analysis the pre-operative POSSUM physiological score (OR = 1.18,P = 0.009) was superior in predicting complications compared to the ASA (P = 0.108), APACHE (P = 0.117)or Childs classification (P = 0.136). In addition, serum sodium, creatinine, international normalized ratio (INR),pulse rate, and intra-operative blood loss were independent risk factors. A combination of the POSSUM variables and INR offered the optimal combination of risk factors for risk prognostication in HPB surgery.CONCLUSION: Morbidity for elective HPB surgery can be accurately predicted and applied in everyday surgical practice as an adjunct in the process of informed consent and for effective allocation of resources for intensive and high-dependency care facilities. | Hemant M Kocher Paris P Tekkis Palepu Gopal Ameet G Patel Simon Cottam Irving S Benjamin | 2005 | World Journal of Gastroenterology2005，11，16： | 3 |
| 2 | An investigation on glycerol biosynthesis by an osmophilie yeast in a bioreaetor 显示文摘 | Sahoo D K Gopal P Agarwal G P | 2001 | Process Biochemistry2001，，36： | 1 |
| 3 | MIR-451 and Ima- tinibmesylate inhibit tumor growth of Glioblastoma stem cells显示文摘 | Hilah G Gopal P Andrew A | 2008 | Biochem Biophys Res Commun2008，8，31： | 1 |
| 4 | A comparative study of time synchronization protocols in wireless sensor networks 显示文摘 | Gopal C G Teek P S | 2011 | International Journal of Applied Engineering Research2011，，4： | 1 |
| 5 | Dose-response effect of Bifidobacteriumlactis HN019on whole gut transit time and functional gastrointestinal symptoms in adults显示文摘 | WALLER P A GOPAL P K LEYER G J | 2011 | Scand J Gastroenterol2011，46，： | 1 |
| 6 | Selection and characterisation of LactobaciUus and Bifidobacterium strains for use as probiotics 显示文摘 | JAYA P SMART H G J GOPAL P K | 1998 | Int Dairy J1998，，8： | 1 |
| 7 | Rapid staining of proteins on polyacrylamide gels and nitrocellulose membranes using a mixture of fluorescent dyes显示文摘 | Gopal G Thallampuranam K S K Shanmugiah T K P | 2000 | J Biochem Biophys Methods2000，46，： | 1 |
| 8 | Comparison of hydroisomerization and hydrocracking reactions of normal and branched octanes over USY and ZSM - 12 Catalysts 显示文摘 | Gopal S Zhang Wenmin Smirniotis P G | 2004 | Ind Eng Chem Res2004，43，： | 1 |
| 9 | A comparative study of time synchronization protocols in wireless sensor networks显示文摘 | Gopal C G Teek P S | 2011 | International Journal of Applied Engineering Research2011，，4： | 1 |
| 10 | Pt/H-ZSM-12 as a catalyst for the hydroisomerization of Cs-C7 n-alkanes and simultaneous satura- tion of benzene显示文摘 | Gopal S Smirniotis P G | 2003 | Appl Catal A2003，247，1： | 1 |
| 11 | Enhanced production of thermostable β-amylase and pullulanase in the presence of surfactants by Clostridium thermosulfurogenes SV2 显示文摘 | Rama Mohan Reddy Gopal Reddy P Seenayya G | 1999 | Process Biochenmisrtry1999，34，： | 1 |
| 12 | Pt/H-ZSM-12 as a catalyst for the hydroisomerization of C5-C7 n-alkanes and simultaneous saturation of benzene显示文摘 | GOPAL S SMIRNIOTIS P G | 2003 | Appl Catal A2003，247，1： | 1 |
| 13 | Analysis of wall glueans from yeast, hypHal and germ-tube forming cells of Candida albicans 显示文摘 | GOPAL P K SULLIVAN P A SHEPHERI) M G | 1984 | J Gen Microbiol1984，130，12： | 1 |
| 14 | Pt/H-ZSM-12 as a catalyst for the hydroisomerization of C5-C7 n-alkanes and simultaneous saturation of benzene显示文摘 | Gopal S Smirniotis P G | 2003 | Applied Catalysis A:General2003，247，1： | 1 |
| 15 | Visualization of fluid flows in virtual environment显示文摘 | Ziegeler S B Gopal G P Blades E etc | 2004 | Journal of Visualization (S1343-8875)2004，7，1： | 1 |
| 16 | Synthesis, anti-HIV and antitubercular activities of lamivudine prodrugs 显示文摘 | Sriram D Yogeeswari P Gopal G | 2005 | Eur J Med Chem2005，40，12： | 1 |
| 17 | Factors Affecting Isomer Yield for n-Heptane Hydroisomerization over As-Synthesized and Dealu- minated Zeolite Catalysts Loaded with Platinum显示文摘 | Gopal S Smirniotis P G | 2004 | J Catal2004，225，2： | 1 |
| 18 | Factors affectig isomer yield for w-heptane hydroisomerization over as-synthesized and dealuminated zeolitecatalysts loaded with platinum显示文摘 | GOPAL S SMIRNIOTIS P G | 2004 | J Catal2004，225，2： | 1 |
| 19 | Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults显示文摘 | Waller P A Gopal P K Leyer G J | 2011 | Scand J Gastroenternl2011，6，9： | 1 |
| 20 | Deactivation behavior of bifunctional Pt/H-Zeolite catalysts during cyclopentane hydroconversion显示文摘 | Gopal S Smirniotis P G | 2002 | Journal of Catalysis2002，205，2： | 1 |
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