|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD显示文摘AIM: To detect a possible association between the polymorphism of the (-670 A/G) Fas/Apo1 gene promoter and susceptibility to Crohn's disease (CD) and ulcerative colitis (UC) in the Tunisian population. METHODS: The (-670 A/G) Fas polymorphism was analyzed in 105 patients with CD, 59 patients with UC, and 100 controls using the polymerase chain reaction restriction fragment length polymorphism method. RESULTS: Significantly lower frequencies of the Fas -670 A allele and A/A homozygous individuals were observed in CD and UC patients when compared with controls. Analysis of (-670 A/G) Fas polymorphism with respect to sex in CD and UC showed a significant difference in A/A genotypes between female patients and controls (P corrected = 0.004 in CD patients and P corrected = 0.02 in UC patients, respectively). Analysis also showed a statistically significant association between genotype AA of the (-670 A/G) polymorphism and the ileum localization of the lesions (P corrected = 0.048) and between genotype GG and the colon localization (Pcorrected = 0.009). The analysis ofinflammatory bowel disease patients according to clinical behavior revealed no difference. CONCLUSION: Fas-670 polymorphism was associated with the development of CD and UC in the Tunisian population. | Walid Ben Aleya Imen Sfar Leila Mouelhi Houda Aouadi Mouna Makhlouf Salwa Ayed-Jendoubi Samira Matri Azza Filali Taoufik Najjar Taeib Ben Abdallah Khaled Ayed Yousr Gorgi | 2009 | World Journal of Gastroenterology2009，15，29： | 3 |
| 2 | Will GnRH antagonists provide new hope for patients considered‘difficult responders′to GnRH agonist protocols?显示文摘 | Craft I Gorgy A Hill J | 1999 | Hum Reprod1999，14，： | 1 |
| 3 | The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses显示文摘 | Zalfa F Gorgi M Primerano B | 2003 | Cell2003，112，3： | 1 |
| 4 | Migration of polybrominated diphenyl ethers in biosolids-amended soil 显示文摘 | Gorgy T Li L Y Grace J R | 2013 | Environmental Pollution2013，172，： | 1 |
| 5 | Growth induced magnetic anisotro- py in amorphous Tb-Fe thin films显示文摘 | Hellman F Gorgy E M | 1992 | Physical Review Let ters1992，68，9： | 1 |
| 6 | Assisted conception following poor ovarian response to gonadotrophin stimulation显示文摘 | Gorgy A Naumann N Bates S | 1997 | Br J Obstet Gynaecol1997，104，12： | 1 |
| 7 | Supercritical CO2 extraction of lycopene and β-carotene from ripe tomatoes 显示文摘 | Enzo C Gorgi G R D Elena M | 2000 | Dys Pigments2000，，44： | 1 |
| 8 | Local heat transfer coefficient forpool boiling of R - 134a and R - 123 on smooth and en-hanced tubes 显示文摘 | Evraam Gorgy | 2012 | International Journal of Heat andMass Transfer2012，55，1112： | 1 |
| 9 | COVID-19 and congenital heart disease:a case series of nine children显示文摘Background Coronavirus disease 2019(COVID-19)is the current pandemic disease without any vaccine or efficient treat-ment to rescue the patients.Underlying diseases predispose the patients to a more severe disease and to a higher mortality rate.However,little evidence exists about COVID-19 outcomes in the pediatric population with congenital heart disease(CHD).Here,we report nine children with COVID-19 and concomitant CHD.Methods Our study included nine children with COVID-19 and concomitant CHD who were admitted to Children Medical Center Hospital during March and April 2020.The patients were classified based on the final outcome(death),and their clinical sign and symptoms,type of CHD,and drugs administered were compared.Results Among the nine patients,two died and we compared different characteristics,laboratory results and clinical findings of these cases based on the mortality.The deceased patients had severe types of CHD,worse arterial blood gases,severe clinical symptoms,higher mean level of partial thromboplastin time and C-reactive protein,and required more medications.Conclusions The present study showed that the general consideration of mild COVID-19 in children does not include patients with CHD and that it is necessary to pay greater attention to children with CHD to determine guidelines for treatment of COVID-19 in these children.Owing to the scarcity of CHD and COVID-19,we reported only nine cases.However,further studies are highly required in this regard. | Elmira Haji Esmaeil Memar Babak Pourakbari Mojtaba Gorgi Meisam Sharifzadeh Ekbatani Amene Navaeian Mahmoud Khodabandeh Shima Mahmoudi Setareh Mamishi | 2021 | World Journal of Pediatrics2021，17，1： | 1 |
| 10 | Association of chemokine and chemokine receptor polymorphisms with activity degree of IBD in Tunisian patients显示文摘 | Gorgi Y Ben Aleya W Sfar I | | 0，，1： | 1 |
| 11 | A comparison between quarter,partial and total laser assisted hatching in selected infertility patients显示文摘 | Podsiadly BT Gorgy A | 2001 | Hum Reprod2001，16，10： | 1 |
| 12 | Development and characterization of novel cathode materials for molten carbonate fuel cell显示文摘 | Gorgi L | 1994 | J Power Sources1994，49，： | 1 |
| 13 | Role of genetic polymorphisms in factor H and MBL genes in Tunisian patients with immunoglobulin A nephropathy显示文摘 | Gorgi Y Hbibi I Sfar I | 2010 | Int J Nephrol Renovasc Dis2010，3，： | 1 |
| 14 | Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia显示文摘AIM:To assess the possible association between PTPN22(R620W) gene polymorphism and inflammatory bowel disease(IBD).METHODS:One hundred and sixty-four patients with IBD 105 Crohn's disease(CD) and 59 ulcerative colitis(UC) and 100 healthy controls were recruited.Genotyping of the PTPN22 gene 1858C→T polymorphism was performed by restriction fragment length polymorphism-polymerase chain reaction with Rsa Ⅰ digestion.RESULTS:The genotypic and allelic frequencies of(R620W) PTPN22 gene polymorphism reveal a significant association of the PTPN22 620-W allele with IBD,compared to the healthy control group(OR:17.81,95% CI:4.18-21.86,P = 0.00001).Nevertheless,nodifference in this polymorphism was found between CD and UC patients.No significant association was found between the frequencies of genotypes of the PTPN22 gene with either the clinical features such as sex,age,age at disease onset,and extent of colitis,or the production of serological markers(anti-Saccharomyces cerevisiae antibody in CD and perinuclear anti-neutrophil cytoplasmic antibody in UC).CONCLUSION:These observations confirm the association of IBD susceptibility with the PTPN22 1858T(620-W) allele in Tunisian patients. | Imen Sfar Walid Ben Aleya Leila Mouelhi Houda Aouadi Thouraya Ben Rhomdhane Mouna Makhlouf Salwa Ayed-Jendoubi Houda Gargaoui Taoufik Najjar Taieb Ben Abdallah Khaled Ayed Yousr Gorgi | 2010 | World Journal of Gastroenterology2010，16，4： | 1 |
| 15 | Risk Factors for Conversion from Laparoscopic to Open Surgery: Analysis of 2138 Converted Operations in the American College of Surgeons National Surgical Quality Improvement Program显示文摘 | Papandria Dominic Lardaro Thomas Rhee Daniel Ortega Gezzer Gorgy Amany Makary Martin A Abdullah Fizan | 2013 | The American Surgeon2013，，9： | 1 |
| 16 | Uniform energy estimates for a semilinear evolution equation of the Mindlin-Timoshenko beam with memory显示文摘 | GORGI C VEGNI F M | 2004 | Mathe- matical and Computer Modelling2004，39，： | 1 |
| 17 | Assisted conception following poor ovarian response to gonadotrophin stimulation 显示文摘 | Gorgy A Naumann N Bates S | 1997 | Br J Obstet Gynaecol1997，104，12： | 1 |
| 18 | Effect of body position on cranial migration of epidurally injected methylene blue in recumbent dogs显示文摘 | Gorgi AA Hofmeister EH Higginbotham MJ | 2006 | Am J Vet Res2006，67，： | 1 |
| 19 | The PTPN22 C1858T ( R620W)functional polymorphism in kidney transplantation 显示文摘 | Sfar I Gorgi Y Aouadi H | 2009 | TransplantProc2009，41，2： | 1 |
| 20 | Human platelet antigens polymorphisms and susceptibility of thrombosis in hemodialysis patients显示文摘 | Gorgi Y Sfar I Ben Aabdallah T | 2008 | Hemodial Int2008，12，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员