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| 1 | Management of digestive bleeding related to portal hypertension in cirrhotic patients:A French multicenter cross-sectional practice survey显示文摘AIM: To investigate the conformity of management practices of gastrointestinal hemorrhage in cirrhotic patients with relevant guidelines. METHODS: A questionnaire on the management of digestive bleeding was completed for all consecutive cirrhotic patients admitted to 31 French hospitals. RESULTS: One hundred and twenty-six bleeding events were recorded. It was the first bleeding episode in 79 patients (63%), of whom 40 (51%) had a prior diagnosis of cirrhosis and 25 (32%) had previously undergone an endoscopy. The bleeding episode was a recurrence in 46 patients (37%). The median time between onset and admission was 4 h, but exceeded 12 h in 42% of cases. There was an agreement between centers forearly vasoactive drug administration (87% of cases), association with ligation (42%) more often than sclerosis (21%) at initial endoscopy, and antibiotic prophylaxis (64%). By contrast, prescription of beta-blockade alone or in combination (0 to 100%, P = 0.003) for secondary prophylaxis and lactulose (26% to 86%, P = 0.04), differed among centers. CONCLUSION: In French hospitals, management of bleeding related to portal hypertension in cirrhotic patients is generally in keeping with the consensus. Broad variability still remains concerning beta-blockade use for secondary prophylaxis. Screening for esophageal varices, the use of antibiotic prophylaxis and patients information need to be improved. | Pierre Ingrand Jérme Gournay Pierre Bernard Frédéric Oberti Brigitte Bernard-Chabert Arnault Pauwels Philippe Renard Eric Bartoli Jean-Franois Cadranel Jean-Claude Barbare Isabelle Ingrand Michel Beauchant | 2006 | World Journal of Gastroenterology2006，12，48： | 4 |
| 2 | In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviralmediated gene transfer:evidence for dedifferentiation of mature hepatocytes显示文摘 | Gournay J Auvigne I Pichard V | 2002 | Lab Invest2002，82，6： | 1 |
| 3 | Prophylactic ibuprofenversus placebo in very premature infants: A randomised,doubleblind 1 placebo-controlled trial 显示文摘 | Gournay V Roze JC Kuster A | 2004 | Lancet2004，364，： | 1 |
| 4 | In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral-mediated gene transfer: evidence for dedifferentiation of mature hepatocytes显示文摘 | GOURNAY J AUVIGUE I PICHARD V | 2002 | Lab Invest2002，82，： | 1 |
| 5 | Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding显示文摘 | Gournay J Masliah C Martin T | 2000 | Hepatology2000，31，： | 1 |
| 6 | Management of anxiety states 显示文摘 | Gournay K | 1995 | Nurs Times1995，91，45： | 1 |
| 7 | In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral-mediated gene transfer:evidence for dedifferentiation of mature hepatocytes显示文摘 | Gournay J Auvigne I Pichard V | 2002 | Lab Invest2002，82，6： | 1 |
| 8 | Optimization of the posterior condylar offset,tib- ial slope,and condylar roll-back in total knee arthroplasty 显示文摘 | Massin P Gournay A | 2006 | Arthroplasty2006，21，6： | 1 |
| 9 | In vivo cell lineage analysis during chemical hapatocarcinogenesis in rats using retroviral-mediated gene transfer: evidence for dedifferentiation of mature hepatocyte 显示文摘 | Gournay J Auvigne I Pichard V | 2002 | Lab Invert2002，82，6： | 1 |
| 10 | In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral-mediated gene transfer:evidence for dedifferentiation of mature hepatocytes显示文摘 | Gournay J Auviqne I Pichard V | 2002 | Lab Invest2002，82，6： | 1 |
| 11 | Mechanisms of adrenomedullin-induced increases of pulmonary blood flow in fetal sheep显示文摘 | Vroomen M Gournay V | 1999 | Pediatr Res1999，45，2： | 1 |
| 12 | In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral-mediated gene transfer:evidence for dedifferentiation of mature hepatocytes显示文摘 | Gournay J Auvigne I Pichard V | 2002 | Lab Invest2002，82，6： | 1 |
| 13 | In vivocell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral - mediated gene transfer :evidence for dedifferentiation of mature hepatocytes显示文摘 | Gournay J Auvigene J Pichard V | 2002 | Lab Invest2002，82，6： | 1 |
| 14 | Prophylactic ibuprofen versus placebo in very premature infants:randomised,doubleblind,placebo-controlledrial显示文摘 | Gournay V Roze JC Kuster A | 2004 | Lancet2004，364，9449： | 1 |
| 15 | Evaluation of quality of life after breast reconstruction using an autologous latissimus dorsi myocutaneous flap显示文摘 | De Gournay E Bonnetain F Tixier H | | 0，，06： | 1 |
| 16 | Synthesis of precision waveforms using a SINIS josephson junction array显示文摘 | MALTRAS F GOURNAY P ROBINSON IAN A | 2007 | IEEE Transactions on Instrumentation and Measurement2007，56，2： | 1 |
| 17 | Perinatal myocardial DNA and protein changes in the lamb: effect of cortisol in the fetus显示文摘 | Rudolph AM Roman C Gournay V | 1999 | Pediatr Res1999，46，2： | 1 |
| 18 | In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral mediatecl gene transfer: evidence for declifferentiation of mature hepatocytes显示文摘 | Gournay J Auvigne I Pichard V | 2002 | Lab Invest2002，82，6： | 1 |
| 19 | Nanometer- scale fea- tures in dolomite from Pennsylvanian rocks, Paradox Basin, Utah 显示文摘 | Gournay J P Kirkland B L Folk R L | 1999 | Sedimentary Geology1999，126，： | 1 |
| 20 | Pulmonary hyperten- sion after ibuprofen prophylaxis in very preterm infants 显示文摘 | Gournay V Savagner C Thirie G | 2002 | Lan- cet2002，359，9316： | 1 |
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