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	题名	作者	年代	出处	被引量
1	Therapeutic potential of targeting the renin angiotensin system in portal hypertension显示文摘Portal hypertension is responsible for the bulk of the morbidity and mortality in patients with cirrhosis.Drug therapy to reduce portal pressure involves targeting two vascular beds.The first approach is to reduce intra hepatic vascular tone induced by the activity of powerful vasocontrictors such as angiotensin Ⅱ,endothelin-1 and the sympathetic system and mediated via contraction of perisinusoidal myofibroblasts and pervascular smooth muscle cells.The second approach is to reduce mesenteric and portal blood flow.Non-selective b-blockers are widely used and have been shown to prolong patient survival and reduce oesophageal variceal bleeding in advanced cirrhosis.However many patients are unable to tolerate these drugs and they are ineffective in a significant proportion of patients.Unfortunately there are no other drug therapies that have proven efficacy in the treatment of portal hypertension and prevention of variceal bleeding.This review briefly outlines current therapeutic approaches to themanagement of portal hypertension,and the evidence supporting the role of the renin angiotensin system(RAS) and the use of RAS blockers in this condition.It will also outline recent advances in RAS research that could lead to the development of new treatments focusing in particular on the recently discovered 'alternate axis' of the RAS.	Chandana B Herath Josephine A Grace Peter W Angus	2013	World Journal of Gastrointestinal Pathophysiology2013，4，1：	9
2	A survey of ampullectomy practices显示文摘AIM:To investigate the endoscopic ampullectomy practices of expert biliary endoscopists.METHODS:An anonymous survey was mailed to 79 expert biliary endoscopists to assess ampullectomy practices.RESULTS:Forty six(58%) biliary endoscopists returned the questionnaire.Of these, 63% were in academia and in practice for an average of 16.4 years(± 8.6).Endoscopists performed an average of 1.1(± 0.8) ampullectomies per month.Prior to ampullectomy, endoscopic ultrasound was'always'utilized by 67% of respondents vs'sometimes'in 31% of respondents.Empiric biliary sphincterotomy was not utilized uniformly, only 26%'always'and 37%'sometimes'performed it prior to resection.Fifty three percent reported'never'performing empiric pancreatic sphincterotomy prior to ampullectomy.Practitioners with high endoscopic retrograde cholangiopancreatography volumes were the most likely to perform a pancreatic sphincterotomy(OR = 10.9;P = 0.09).Participants overwhelmingly favored'always'placing a prophylactic pancreatic stent, with 86% placing it after ampullectomy rather than prior to resection(23%).Argon plasma coagulation was the favored adjunct modality(83%) for removal of residual adenomatous tissue.Practitioners uniformly(100%) preferred follow-up examination to be within 6 mo post-ampullectomy.CONCLUSION:Among biliary experts, there is less variation in ampullectomy practices than is reflected in the literature.	Stacy B Menees Philip Schoenfeld Hyungjin Myra Kim Grace H Elta	2009	World Journal of Gastroenterology2009，15，28：	2
3	Hydrodynamics of spouted and spout-fluidized beds at high temperature 显示文摘	Ye B Lim C J Grace J R	1992	The Canadian Journal of Chemical Engineering1992，70，5：	2
4	Role of Small Bowel Follow-through in Diagnosing Inflammation of the Terminal Ileum in Pediatric Patients显示文摘	Matthew Stenerson Eric Vittinghoff Melvin B Heyman Grace E Kim Neera Gupta	2010	Journal of Pediatric Gastroenterology and Nutrition2010，，4：	2
5	The epidemiology of dermatomyositis in South Australia显示文摘	VIDYA L PETER B GRACE S	2007	APLAR J Rheumatol2007，10，：	1
6	The relationship between species density and community biomazs in grazed and ungrazed coastal meadows显示文摘	Grace J B Jutila H	1999	Oikos1999，85，2：	1
7	Sequence and spacing of TATA box elements are critical for accurate initiation from the β-phaseolin promoter显示文摘	GRACE M L CHANDRASEKHARAN M B HALL T C CROWE A J	2004	Biological Chemistry2004，279，：	1
8	Recovery characteristics following induction of anaesthesia with a combination of thiopentone andpropofol 显示文摘	Rashiq S Gallant B Grace M	1994	Can J Anaesth1994，41，12：	1
9	Acute lym-phoblastic leukemia and Klinefelter's syndrome 显示文摘	SHAW M P EDEN O B GRACE E	1992	Pediatr Hematol Oncol1992，9，：	1
10	On the measurement of plant competition intensi- ty 显示文摘	GRACE J B	1995	Ecology1995，76，1：	1
11	An oscillation critarion for certain second order strcngly sublinear differental Equations显示文摘	Grace S R Lalli B S	1987	J Math Anal Appl1987，123，：	1
12	Factors associated with plant species richness in a coastal tall-grass prairie显示文摘	GRACE J B ALLAIN L K ALLEN C	2000	Journal of Vegetation Science2000，11，：	1
13	Oscillation theorems for n-th order delay differential Equations显示文摘	Grace S R Lalli B S	1983	J Math Anal Appl1983，，1：	1
14	Patterna of CDKN2A Gene Loss in Sequential Oral Epithelial Dysplasias and Carcinomas显示文摘	S Ali S Grace B Joseph A	2003	Cancer Research2003，61，：	1
15	Integral averaging techniques for the oscillation of second order nonlinear differential equations显示文摘	GRACE S R LALLI B S	1990	J Math Anal Appl1990，149，：	1
16	Biology of invasive termites : a worldwide review显示文摘	Evans T A Forschler B T Grace J K	2013	Ann Rev Entomol2013，58，：	1
17	Elevated CO2enhances biological contributions to elevation change in coastal wetlands by offsetting stressors associated with sea-level rise显示文摘	CHERRY J A MEKEE K L GRACE J B	2009	Journal of Ecology2009，97，：	1
18	The effects of gap size and disturbance type on invasion of wet pine savanna by eogongrass, I~ata cylindrica ( Poaeeae) 显示文摘	King S E Grace J B	2000	Am J Bot2000，87，：	1
19	Long Term Dynamics of Tip- pah Populations 显示文摘	GRACE J B WETZEL R G	1998	Aquat Bot1998，61，：	1
20	Full-Scale Test of Prestressed Double-Tee Beam 显示文摘	Nabil F Grace George Abdel-Sayed Frederick C Navarre Richard B Nacey Wayne Bonus Loris Collavino	2003	Concrete International2003，，4：	1

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