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2篇 您的检索式:作者名="Grace Guzman"
    题名 作者 年代 出处 被引量
1Does Nonalcoholic Fatty Liver Disease Predispose Patients to Hepatocellular Carcinoma in the Absence of Cirrhosis?显示文摘Guzman Grace Brunt Elizabeth M Petrovic Lydia M Chejfec Gregorio Layden Thomas J Cotler Scott J 2008Archives of Pathology & Laboratory Medicine2008,,11:2
2Immunoglobulin G4 associated autoimmune cholangitis and pancreatitis following the administration of nivolumab:A case report显示文摘BACKGROUND Immune checkpoint inhibitors have significantly improved survivals for an increasing range of malignancies but at the cost of several immune-related adverse events,the management of which can be challenging due to its mimicry of other autoimmune related disorders such as immunoglobulin G4(IgG4)related disease when the pancreaticobiliary system is affected.Nivolumab,an IgG4 monoclonal antibody,has been associated with cholangitis and pancreatitis,however its association with IgG4 related disease has not been reported to date.CASE SUMMARY We present a case of immune-related pancreatitis and cholangiopathy in a patient who completed treatment with nivolumab for anal squamous cell carcinoma.Patients IgG4 levels was normal on presentation.She responded to steroids but due to concerns for malignant biliary stricture,she opted for surgery,the pathology of which suggested IgG4 related disease.CONCLUSION We hypothesize this case of IgG4 related cholangitis and pancreatitis was likely triggered by nivolumab.Rohit Agrawal Grace Guzman Saman Karimi Pier Cristoforo Giulianotti Alfredo Jose Mena Lora Shikha Jain Meshaal Khan Brian R Boulay Yolande Chen 2022World Journal of Clinical Cases2022,10,20:1
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