| 2 | Enantioselective construction of a congested quaternary stereogenic center in isoindolinones bearing three aryl groups via an organocatalytic formal Betti reaction显示文摘An efficient enantioselective formal Betti reaction between phenols and diaryl ketimines generated in situ from isoindolinone alcohols is described.In a reaction catalyzed by a chiral phosphoric acid,a broad range of ketimines and phenols afforded isoindolinone derivatives comprising a congested quaternary stereogenic center bearing three aryl groups in high yields,and high regioselectivities and enantioselectivities. | Arben Berisa Danijel Glavac Chao Zheng Shu-Li You Matija Gredicak | 2022 | Organic Chemistry Frontiers2022，9，2： | 0 |
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