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    题名 作者 年代 出处 被引量
1曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M 2001中国疼痛医学杂志2001,7,1:2
2Effect of Endostatin on Spontaneous Tumorigenesis of Mammary Adenocarcinomas in a Transgenic Mouse Model显示文摘Yokoyama Y Green J E Sukhatme V P 2000Cancer Res2000,60,16:1
3Enhanced avidity maturation of antibody to human immunodeficiency virus envelope: DNA vaccination with gp120-C3d fusion proteins显示文摘Ross T M Xu Y Green T D 2001AIDS Res Hum Retrovirus2001,17,9:1
4Three clonal types of keratinocyte with different capacities for multiplication显示文摘Barrandon Y Green H 1987Proc Natl Acad Sci USA1987,84,8:1
5Solar cell efficiency ta- bles显示文摘Green M A Emery K Hishikawa Y 2012Res Appl2012,20,:1
6Three clonal types of keratinocyte with different capacities for multiplication显示文摘BARRANDON Y GREEN H 1987Proc Natl Aead Sci USA1987,84,:1
7Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G:a non-pathogenic Nef mutant-based antiHIV strategy显示文摘Green LA Liu Y He JJ 2009J Biol Chem2009,284,13:1
8Ductility and Cracking Behavior of Prestressed Concrete Beams Strengthened with Prestressed CFRP Sheets 显示文摘KIM Y J SHI C GREEN M F 2008Journal of Composites for Construction2008,12,3:1
9A simple chemical method of opening and filling carbon nanotubes显示文摘TSANG S C CHEN Y K GREEN M L H 1994Nature1994,372,:1
10Synthesis of carbon nanorubes filled with long continuous crystals of molybdenum oxides显示文摘CHEN Y K GREEN M L H TSANG S C 1996Chem Commun1996,21,:1
11Cortical sensorimotor reorganization after spinal cord injury: an electroencephalographic study显示文摘Green JB Sora E Bialy Y 1998Neurology1998,50,4:1
12Solar cell efficiency tables (Version 38) 显示文摘Green M A Emery K Hishikawa Y 2011Prog Photovolt: Res Appl2011,19,:1
13Growth responses of three coexisting conifer species to climate across wide geographic and climate ranges in Yukon and British Columbia显示文摘Miyamoto Y Griesbauer H P Scott Green D 2010Forest E- cology and Management2010,259,3:1
14Visualization of feline calicivirus replication in real-time with recombinant viruses engineered to express fluorescent reporter proteins显示文摘Abente E J Sosnovtsev S V Bok K Green K Y 2010Virology2010,400,1:1
15Recovery and altered neutralization specificities of chimeric viruses containing capsid protein domain exchanges from antigenically distinct strains of feline calicivirus显示文摘Neill J D Sosnovtsev S V Green K Y 2000Virol2000,74,3:1
16Microglial activation in human diabetic retinopathy显示文摘ZENG H Y GREEN W R TSO M O 2008Arch Ophthalmol2008,126,2:1
17Pancreatic lymph nede-derived CD4^+ 25^+ T reg cells:highly potent regulators of diabetes that require TRANCE-RANK signals显示文摘Green EA Choi Y Flavell RA 2002Immunity2002,16,2:1
18Chlamydia-Infected Cells Continue To Undergo Mitosis and Resist Induetion of Apoptosis 显示文摘Greene M Xion Y Huang Y 2004Infection and Imm unity2004,72,:1
19Cytochrome c:functions beyond respiration显示文摘Ow Y P Green D R Hao Z 0,,07:1
20Enhanced avidity maturation of antibody to human immunodeficiency virus envelope: DNA vaccination with gp120-C3d fusion proteins显示文摘 Xu Y Green TD 2001Aids Research and Human Retroviruses2001,17,9:1
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