|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 普萘洛尔和类固醇激素治疗婴幼儿血管瘤疗效及安全性的比较:随机临床试验显示文摘关于普萘洛尔和类固醇激素治疗婴幼儿血管瘤(IH)疗效及安全性比较的随机临床试验数据十分有限。该文作者在一所大学的医院进行了上述临床试验。2013年6月—2014年10月间被诊断为IH的患者纳入研究,这些患者心功能正常,之前未接受过治疗。 | Kim KH Choi TH Choi Y 张凌 | 2017 | 中国口腔颌面外科杂志2017，15，3： | 14 |
| 2 | 4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8^(+) T cell proliferation显示文摘4-1BB(CD137)is a strong enhancer of the proliferation of CD8^(+)T cells.Since these cells require increased production of energy and biomass to support their proliferation,we hypothesized that 4-1BB signaling activated glucose and fatty acid metabolism.We found that treatment with agonistic anti-4-1BB mAb promoted the proliferation of CD8^(+)T cells in vitro,increasing their size and granularity.Studies with a glycolysis inhibitor and a fatty acid oxidation inhibitor revealed that CD8^(+)T cell proliferation required both glucose and fatty acid metabolism.Anti-4-1BB treatment increased glucose transporter 1 expression and activated the liver kinase B1(LKB1)-AMP-activated protein kinase(AMPK)-acetyl-CoA carboxylase(ACC)signaling pathway,which may be responsible for activating the metabolism of glucose and fatty acids.We also examined whether blocking glucose or fatty acid metabolism affected cell cycle progression and the anti-apoptotic effect of 4-1BB signaling.The increase of anti-apoptotic factors and cyclins in response to anti-4-1BB treatment was completely prevented by treating CD8^(+)T cells with the fatty acid oxidation inhibitor,etomoxir,but not with the glycolysis inhibitor,2-deoxy-D-glucose.We conclude that anti-4-1BB treatment activates glucose and fatty acid metabolism thus supporting the increased demand for energy and biomass,and that fatty acid metabolism plays a crucial role in enhancing the cell cycle progression of anti-CD3-activated CD8^(+)T cells in vitro and the anti-apoptotic effects of 4-1BB signaling on these cells. | Beom K Choi Do Y Lee Don G Lee Young H Kim Seon-Hee Kim Ho S Oh Chungyong Han Byoung S Kwon | 2017 | Cellular & Molecular Immunology2017，14，9： | 6 |
| 3 | Tracking domestic ducks:A novel approach for documenting poultry market chains in the context of avian influenza transmission显示文摘Agro-ecological conditions associated with the spread and persistence of highly pathogenic avian influenza(HPAI) are not well understood, but the trade of live poultry is suspected to be a major pathway. Although market chains of live bird trade have been studied through indirect means including interviews and questionnaires, direct methods have not been used to identify movements of individual poultry. To bridge the knowledge gap on quantitative movement and transportation of poultry, we introduced a novel approach for applying telemetry to document domestic duck movements from source farms at Poyang Lake, China. We deployed recently developed transmitters that record Global Positioning System(GPS) locations and send them through the Groupe Spécial Mobile(GSM) cellular telephone system. For the first time, we were able to track individually marked ducks from 3 to 396 km from their origin to other farms, distribution facilities, or live bird markets. Our proof of concept test showed that the use of GPS-GSM transmitters may provide direct, quantitative information to document the movement of poultry and reveal their market chains. Our findings provide an initial indication of the complexity of source-market network connectivity and highlight the great potential for futuretelemetry studies in poultry network analyses. | Chang-Yong Choi John Y Takekawa XIONG Yue LIU Ying Martin Wikelski George Heine Diann J Prosser Scott H Newman John Edwards Fusheng Guo Xiangming Xiao | 2016 | Journal of Integrative Agriculture2016，15，7： | 3 |
| 4 | Bone induction by BMP-2 transduced stem cells derived from human fat显示文摘 | Dragoo J L Choi J Y Lieberman J R Huang J, Zuk P A, Zhang J, Hedrick M H, Benhaim P | | 0，，： | 2 |
| 5 | Some remarks on a singular elliptic boundary value problem显示文摘 | Choi Y S Lazer A C McKenna P J | 1998 | Nonlinear Analysis Theory Methods and Applications1998，32，3： | 2 |
| 6 | All-optical clock recovery from NRZ data with simple NRZ-to-PRZ converter based on self-modulation of semiconductor optical amplifier显示文摘 | Lee H J Kim H G Choi J Y | 1999 | Electronics Letters1999，35，12： | 2 |
| 7 | Immunogenicity of the E1E2 proteins of hepatitis C virus expressed by recombinant adenoviruses 显示文摘 | Seong Y R Choi S Lim J S | 2001 | Vaccine2001，19，2022： | 2 |
| 8 | 皮质酮通过抑制GAS6表达调控毛囊干细胞静止显示文摘长期持续性的精神压力会显著影响毛发组织的稳态和毛发再生,但其作用机制尚不清楚。最近发表在Nature杂志的研究表明,Mao等在小鼠体内证实了压力激素皮质酮(等同于人体内皮质醇)可调节毛囊干细胞(HFSC)静止和毛发生长。既往研究发现糖皮质激素受体(皮质酮受体)和肾上腺(分泌皮质酮)可以影响小鼠毛发生长,而毛囊的静止期(telogen)和生长期(anagen)周期性变化伴随着HFSC的休眠和激活,作者由此推测皮质酮可能通过控制HFSC活化调节毛发生长。 | 张淼旻(编译) Choi S Zhang B Hsu Y | 2021 | 国际老年医学杂志2021，42，6： | 2 |
| 9 | A robust approach to image enhancement based on fuzzy logic显示文摘 | Choi Y S Krishnapuram R | 1997 | IEEE Transaction on Image Processing1997，6，6： | 2 |
| 10 | The supply base and its complexity: Implications for transaction costs, risks, responsiveness, and innovation显示文摘 | Choi T Y Krause D R | 2006 | Journal of Operations Management2006，24，5： | 1 |
| 11 | Initial cation stoichiometry and current-voltage behavior in Sc-doped calcium copper titanate 显示文摘 | CHUNG S Y LEE S I CHOI J H | 2006 | Appl Phys Lett2006，89，19： | 1 |
| 12 | Polymer-polymer miscibility study for plastic gradient index optical fiber 显示文摘 | LEE B CHOI W Y WALKER J K | 2000 | Polym Eng Sci2000，40，9： | 1 |
| 13 | Ruthenium Bipyridyl Complex-sensitized Dechlorination of in Aqueous Mieellar Solutions under Visible Light显示文摘 | CHO Y PARK Y CHOI W Y | 2008 | Journal of Industrial and Engineering Chemistry2008，14，： | 1 |
| 14 | Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells显示文摘 | Kim Y A Choi B T Lee Y T | 2004 | Oncol Rep2004，11，2： | 1 |
| 15 | Existence of global solutions for the Shigesada-Kawasaki-Teramoto model with weak cross-diffusion显示文摘 | Choi Y S Lui R Yamada Y | 2003 | Discrete Contin Dynam Systems2003，9，5： | 1 |
| 16 | Modulation of skin collagen metabolism in aged and photoaged human skin in vivo显示文摘 | Chung J H Seo J Y Choi H R | 2001 | J Invest Dermatol2001，117，5： | 1 |
| 17 | Field experiments on mitigation of harmful algal blooms using a Sophorolipid-Yellow clay mixture and effects on marine plankton 显示文摘 | LEE Y J CHOI J K KIM E K | 2008 | Harmful Algae2008，7，： | 1 |
| 18 | Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin 显示文摘 | Choi JA Kim J Y Lee JY | 2001 | Int J Oncol2001，19，4： | 1 |
| 19 | 3D welding and milling:Part I-a direct approach for freeform fabrication of metallic prototypes显示文摘 | Song Y A Park S Choi D | 2005 | International Journal of Machine Tools and Manufacture2005，45，9： | 1 |
| 20 | Antisense Inhibition of Macrophage Inflammatory Protein 1-α Blocks Bone Destruction in a Model of Myeloma Bone Disease 显示文摘 | Choi S J Oba Y Gazitt Y | 2001 | J Clin Invest2001，108，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员