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248篇 您的检索式:作者名="Gregorio E"
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1Portopulmonary hypertension and serum endothelin levels in hospitalized patients with cirrhosis显示文摘BACKGROUND:Cirrhosis is associated with several extrahepatic manifestations including portopulmonary hypertension (PPHT).Recent data suggest that endothelins (ETs) are related to the pathophysiology of PPHT.The study aimed to measure serum ET levels in hospitalized cirrhotic patients and to determine their association with PPHT and patient outcome.METHODS:Fifty-seven cirrhotic patients [43 males;median age 58 (28-87) years] underwent Doppler echocardiography.Patients with systolic pulmonary arterial pressure ≥40 mmHg and pulmonary acceleration time <100 ms were deemed to have PPHT.ET-1,2,and 3 serum levels were measured with an ELISA assay.All-cause mortality was recorded over a median period of 24 months.RESULTS:Nine out of 57 patients (15.8%) had PPHT.Among various clinical variables,only autoimmune hepatitis was associated with PPHT (OR=11.5;95% CI,1.58-83.4;P=0.01).ET-1 levels [9.1 (1.6-20.7) vs 2.5 (1.4-9.2) pg/mL,P=0.02] and the ET-1/ET-3 ratio [4.73 (0.9-22.4) vs 1.6 (0.3-10.7),P=0.02] were significantly higher in patients with PPHT than in those without.ET-2 and ET-3 levels did not differ between the two groups.There was no difference in survival between the two groups,although ET-1 levels were associated with an adverse outcome in Cox regression analysis (HR=1.11;95% CI,1.02-1.22;P=0.02 per unit increase in ET-1).CONCLUSION:Our data suggest that ET-1 and the ET-1/ET-3 ratio are elevated in patients with PPHT and that ET-1 is associated with a poor outcome irrespective of PPHT.Aristotelis Tsiakalos Gregorios Hatzis Ioannis Moyssakis Aggelos Karatzaferis Panayiotis D Ziakas George E Tzelepis 2011Hepatobiliary & Pancreatic Diseases International2011,10,4:7
2How does Foreign Direct Investment Affect Economic Growth?显示文摘E Borensztein J De Gregorio J -W Lee 1998Journal of International Economics1998,,45:1
3Effect of crystalline phase, ori- entation and temperature on the dielectric properties of poly (vinylidene fluoride) (PVDF) 显示文摘Gregorio R Ueno E M 1999J Appl Polym Sci1999,34,:1
4Vibrant soundbridge in congenital osseous atresia: multicenter study of' 12 patients with osseous atrcsia 显示文摘Zemotti M E Arauz S L Di Gregorio M F 2013Acta Otolaryngol2013,133,6:1
5How does for- eign direct investment affect economic growth 显示文摘Borensztein E Gregorio J D Lee J W 1998Jour- nal of International Economics1998,45,:1
6International new ventures:the cross-border nexus of individuals and opportunities显示文摘Gregorio D D Musteen M Thomas D E 0,,02:1
7Characterizing the Saltol quantitative trait locus for salinity tolerance in rice 显示文摘Thomson M J Ocampo M Egdane J Rahman M A Sajise A G Adorada D L Tumimbang-Raiz E Blumwald E Seraj Z I Singh R K Gregorio G B Ismail A M 2010Rice2010,3,2:1
8Acute colorectal obstruction:treatment with self-expandable metallic stents before scheduled surgery:results of a multicenter study显示文摘Mainar A De Gregorio M A Tejero E 1999Radiology1999,210,1:1
9Financial development and economic growth显示文摘De Gregorio Guidotti E 1995World Development1995,23,3:1
10How Does Foreign Direct Investment Affect Economic Growth? 显示文摘BORENSZTEIN E GREGORIO J LEE J - W 1998Journal of International Economics1998,45,:1
11Desenvolvimento Das Gonadas de Dermatobia hominis(Diptera:Cuterebridae)显示文摘LELLO E D GREGORIO E A TOLEDO L A 1985Mem Inst Oswaldo Cruz1985,80,2:1
12How does Foreign Direct Investment Affect Economic Growth? 显示文摘Borensztein E Gregorio J D Lee J - W 1998Journal of International Economics1998,45,:1
13MF59 adjuvant:the best insurance against influenza strain diversity显示文摘O'HAGAN D T RAPPUOLI R DE GREGORIO E 2011Expert Rev Vaccines2011,10,4:1
14Molecular diagnosis of infective endocarditis by re- al-time broad-range polymerase chain reaction (PCR) and sequencing directly from heart valve tissue 显示文摘Marin M Mufioz P Sdnchez M del Rosal M Alcal6 L Rodrlguez-Cr6ixems M Bouza E Group for the Manage- ment of Infective Endocarditis of the Gregorio Marafi6n Hospital 2007Medicine2007,86,4:1
15The path to a successful vaccine adjuvant-'The long and winding road显示文摘O' Hagan DT De Gregorio E 0,,11:1
16Organizational Learning Dynamics in the Software Publishing Industry显示文摘Pedro L Gregorio M Jose E N 2008International Journal of Technology Management2008,41,12:1
17Defaunating capacity of tropical fodder trees: Effects of polyethylene glycol and its relationship to in vitro gas production 显示文摘Gregorio E M B Carlos A S C 2005Animal Feed Science and Technology2005,123,1:1
18How does foreign direct investment affect economic growth? 显示文摘Borenztein E Gregorio D Lee J 1998Journal of International Economics1998,45,1:1
19How does foreign direct in- vestment affect economic growth? 显示文摘BORENSZTEIN E GREGORIO LEE 1998Journal of International Eco- nomics1998,,45:1
20Lipid in invasive cancer of the breast显示文摘Fisher E R Gregorio R Kim W S 1977Am J Clin Path1977,68,:1
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