|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans显示文摘Background:Large numbers of post-deployment U.S.veterans are diagnosed with post-traumatic stress disorder(PTSD)and/or traumatic brain injury(TBI),leading to an urgent need for effective interventions to reduce symptoms and increase veterans’coping.PTSD includes anxiety,flashbacks,and emotional numbing.The symptoms increase health care costs for stress-related illnesses and can make veterans’civilian life difficult.Methods:We used a randomized wait-list controlled design with repeated measures of U.S.military veterans to address our specific aim to test the efficacy of a 6-week therapeutic horseback riding(THR)program for decreasing PTSD symptoms and increasing coping self-efficacy,emotion regulation,social and emotional loneliness.Fiftyseven participants were recruited and 29 enrolled in the randomized trial.They were randomly assigned to either the horse riding group(n=15)or a wait-list control group(n=14).The wait-list control group experienced a 6-week waiting period,while the horse riding group began THR.The wait-list control group began riding after 6 weeks of participating in the control group.Demographic and health history information was obtained from all the participants.PTSD symptoms were measured using the standardized PTSD Checklist-Military Version(PCL-M).The PCL-M as well as other instruments including,The Coping Self Efficacy Scale(CSES),The Difficulties in Emotion Regulation Scale(DERS)and The Social and Emotional Loneliness Scale for Adults-short version(SELSA)were used to access different aspects of individual well-being and the PTSD symptoms.Results:Participants had a statistically significant decrease in PTSD scores after 3 weeks of THR(P≤0.01)as well as a statistically and clinically significant decrease after 6 weeks of THR(P≤0.01).Logistic regression showed that participants had a 66.7%likelihood of having lower PTSD scores at 3 weeks and 87.5%likelihood at 6 weeks.Under the generalized linear model(GLM),our ANOVA findings for the coping self-efficacy,emotion regulation,and social and emotional loneliness did not reach statistical significance.The results for coping self-efficacy and emotion regulation trended in the predicted direction.Results for emotional loneliness were opposite the predicted direction.Logistic regression provided validation that outcome effects were caused by riding longer.Conclusion:The findings suggest that THR may be a clinically effective intervention for alleviating PTSD symptoms in military veterans. | Rebecca A.Johnson David L.Albright James R.Marzolf Jessica L.Bibbo Hayley D.Yaglom Sandra M.Crowder Gretchen K.Carlisle Amy Willard Cynthia L.Russell Karen Grindler Steven Osterlind Marita Wassman Nathan Harms | 2018 | Military Medical Research2018，5，1： | 3 |
| 2 | State-mandated insurance coverage is associated with the approach to hydrosalpinges before IVF显示文摘 | Kenan Omurtag Natalia M. Grindler Kimberly A. Roehl G. Wright Bates Angeline N. Beltsos Randall R. Odem Emily S. Jungheim | 2014 | Reproductive BioMedicine Online2014，，： | 1 |
| 3 | Maternal obesity, infertility and mitochondrial dysfunction: potential mechanisms emerging from mouse model systems显示文摘 | Grindler NM Moley KH | | Mol Hum Reprod0，19，8： | 1 |
| 4 | Focusing: An adjunct treatment for adaptive recovery from cancer显示文摘 | Grindler Katonah D | 1997 | Focusing Folio1997，18，： | 1 |
| 5 | The role of Stenotroph- omonas mal-tophilia in refractory chronic rhinosinusitis 显示文摘 | Grindler D Thomas C Hall GS | 2010 | Am J Rhinol Allergy2010，24，3： | 1 |
| 6 | The role of Stenotrophomonas maltophilia in refractory chronic rhinosinusitis显示文摘 | GRINDLER D THOMAS C HALL G S | 2010 | Am J Rhinol Allergy2010，24，： | 1 |
| 7 | The role of Stenotrophomonas maltophilia in refractory chronic rhinosinusitis显示文摘 | Grindler D Thomas C Hall GS | 2010 | Am J Rhinol Allergy2010，24，3： | 1 |
| 8 | Impact of Otitis Media Severity on Children's Quality of Life 显示文摘 | Grindler DJ Blank SJ Schulz KA | 2014 | Otolaryngol Head Neck Surg2014，151，2： | 1 |
| 9 | Changes of the liver metabolome following an intravenous lipopolysaccharide injection in Holstein cows supplemented with dietary carnitine显示文摘Background:Carnitine facilitates the flux of long-chain fatty acids for hepatic mitochondrial beta-oxidation,which acts to ameliorate the negative energy balance commonly affecting high-yielding dairy cows.Inflammation triggered by lipopolysaccharide(LPS)load can however pose a challenge to the metabolic integrity via the expression of pro-inflammatory mediators,leading to immune system activation and respective metabolic alterations.The effect of enhanced carnitine availability on hepatic metabolome profiles during an inflammatory challenge has not yet been determined in dairy cows.Herein,Holstein cows were supplemented with 25 g/d rumen-protected carnitine from 42d prepartum until 126 d postpartum(n=16)or assigned to the control group with no supplementation during the same period(n=14).We biopsied the liver of the cows before(100 d postpartum)and after(112 d postpartum)an intravenous injection of 0.5μg/kg LPS.Liver samples were subjected to a targeted metabolomics analysis using the AbsoluteIDQ p180 Kit(Biocrates Life Sciences AG,Innsbruck,Austria).Results:Multivariate statistical analyses revealed that hepatic metabolome profiles changed in relation to both the carnitine supplementation and the LPS challenge.Comparing the metabolite profiles on 100 d,carnitine increased the concentration of short-and long-chain acyl-carnitines,which may be explained by an enhanced mitochondrial fatty acid shuttle and hence greater energy availability.The LPS injection affected hepatic metabolite profiles only in the carnitine supplemented group,particularly altering the concentration of biogenic amines.Conclusions:Our results point to interactions between an acute hepatic inflammatory response and biogenic amine metabolism,depending on energy availability. | Wei Xu Sandra Grindler Akos Kenez Sven Danicke Jana Frahm Korinna Huber | 2023 | Journal of Animal Science and Biotechnology2023，14，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员