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| 1 | Epithelioid hemangioendothelioma of the liver as a rare indication for liver transplantation显示文摘AIM: To investigate the indications and outcomes of liver transplantation for hepatic epithelioid hemangioendothelioma(HEHE). METHODS: Between 1989 and August 2013, in the Department of General, Transplant, and Liver Surgery, Medical University of Warsaw, 1306 orthotopic liver transplantations(OLTx) were performed, including 72 retransplantations. Unresectable HEHE was an indication for OLTx in 10 patients(0.8% of primary OLTx), the mean age of the patients was 40.5 ± 13.3 years(range 23-65 years), and the male-to-female ratio was 2:8. Kaplan-Meier survival analysis in HEHE, hepatocellular carcinoma(HCC), and other OLTx recipients groups was performed. The differences in mortality were compared using the χ2 test. A P-value < 0.05 indicated statistical significance.RESULTS: No concomitant liver disease was found in any patient. There was no neoadjuvant chemotherapy or radiotherapy. Liver function test results were normal in most of the patients. The levels of alpha-fetoprotein, carcinoembryonic antigen, and carbohydrate antigen 19-9 were normal. In immunohistochemical staining, the neoplastic cells were positive for factor Ⅷ-related antigen, CD31, and CD34, which are endothelial cell markers, and negative for cytokeratin 19, cytokeratin 7, and HepPar-1. Nine patients were alive without tumor recurrence. One patient died 2 mo after OLTx due to septic complications. No morbidity was observed. Maximum follow-up was 11.4 years, with a minimum of 1 mo. The cumulative survival rate at the end of followup in HEHE patients was 87.5% compared with 54.3% in the HCC group and 76.3% in the other OLTx recipients group(χ2 test = 1.784, df = 2, P = 0.409).CONCLUSION: Unresectable HEHE, without extrahepatic metastases is an excellent indication for liver transplantation. Long-term survival is very good and much better than in HCC patients and the entire group of OLTx patients. | Piotr Remiszewski Ewa Szczerba Piotr Kalinowski Beata Gierej Krzysztof Dudek Mariusz Grodzicki Marcin Kotulski Rafa Paluszkiewicz Waldemar Patkowski Krzysztof Zieniewicz Marek Krawczyk | 2014 | World Journal of Gastroenterology2014，20，32： | 10 |
| 2 | Factors associated with intensification of antihypertensive drug therapy in patients with poorly controlled hypertension显示文摘Objective To assess antihypertensive management of older patients with poor blood pressure(BP)control.Methods Physicians,voluntary participating in the study,included six consecutive hypertensive patients during routine visits.Hypertension had to have been previously recognized and averaged office BP was>140 and/or>90 mmHg in spite of>6 weeks of antihypertensive therapy.The physicians completed a questionnaire on patients'history of cardiovascular(CV)risk factors,comorbidities,home BP monitoring,anthropometric data and the pharmacotherapy.Results Mean age of the 6462 patients was 61 years,7%were>80 years,51%were female.Mean士SD office BP values were 158士13/92土10 mmHg.The most commonly prescribed antihypertensive drugs were:diuretics(67%),ACE inhibitors(64%),calcium channel blockers(58%)and卩-blockers(54%),and their use increased with age.On monotherapy or dual therapy,43%of the patients and 40%had their latest treatment modification within six months.Home BP monitoring was a factor that accelerated the modification of the therapy.Older patients had to have less chance on faster modification of antihypertensive therapy in spite of presence of diabetes and higher systolic BP.Conclusions Our study suggests that a large number of outpatients with poor BP control receive suboptimal antihypertensive therapy,especially in primary care.In older patients,higher BP values in the office settings are more frequently accepted by physicians even in case of higher CV risk.Regular home BP monitoring hastens the decision to intensify of antihypertensive treatment. | Olga Siga Barbara Wizner Barbara Gryglewska Jolanta Walczewska Tomasz Grodzicki | 2019 | Journal of Geriatric Cardiology2019，16，1： | 2 |
| 3 | Pulse wave velocity and the estimated risk of stroke and myocardial infarction 显示文摘 | Grodzicki T Cwynar M Gasowski J | 2002 | Acta Cardiol2002，57，1： | 1 |
| 4 | Vascular complications after liver transplantation显示文摘 | Pawlak J Grodzicki M Leowska E | 2003 | Transplant Proc2003，35，6： | 1 |
| 5 | Heteronuclear multiple-quantum correlation 15N-1H,cross-polarized magic angle spinning 13C,15N nuclear magnetic resonance and infrared spectroscopic studies of 1,2,4-triazolo--pyrimidine and its Zn (Ⅱ) halid and thiocyanate complexes显示文摘 | Szlyk E Grodzicki A Pazderski L | 2000 | Polyhedron2000，19，： | 1 |
| 6 | Comparison of directfluorescent antibody staining and real-time polymerase chain reaction forthe detection of Borrelia burgorferi in Ixodes scapularis ticks显示文摘 | GAUMOND G TYROPOLIS A GRODZICKI S | 2006 | J Vet Di-agn Invest2006，18，6： | 1 |
| 7 | Vasular complications after fiver transplkantation显示文摘 | Pawlak J Grodzicki M Leowska E | 2003 | Transplant Proc2003，35，： | 1 |
| 8 | Influence of Selected Factors on Survival After Liver Retransplantation显示文摘 | P. Remiszewski P. Kalinowski K. Dudek M. Grodzicki R. Paluszkiewicz K. Zieniewicz M. Krawczyk | 2011 | Transplantation Proceedings2011，，8： | 1 |
| 9 | Vascular complications after liver transplantation 显示文摘 | Pawlak J Grodzicki M Leowska E | 2003 | Transplant Proc2003，35，6： | 1 |
| 10 | Vascular complications after liver transplantation显示文摘 | Pawlak J Grodzicki M Leowska E | 2003 | Transplantation Proceedings2003，35，6： | 1 |
| 11 | The spirochetal etiology of Lyme disease显示文摘 | Steere A C Grodzicki R L Kornblatt A N | 1983 | N Engl J Med1983，308，： | 1 |
| 12 | Tra- ditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythemato- sus显示文摘 | Esdaile J M Abrahamowicz M Grodzicky T | 2001 | Arthritis Rheum2001，44，10： | 1 |
| 13 | Strong association of au-toantibodies to human nuclear lamin B1 with lupus anticoagulantantibodies in systemic lupus erythematosus显示文摘 | Senecal JL Rauch J Grodzicky T | 1999 | Arthritis Rheum1999，42，7： | 1 |
| 14 | Salt and hypertension:is salt dietary reduction worth the effort?显示文摘 | Frisoli TM Schmieder RE Grodzicki T | 2012 | Am J Med2012，125，5： | 1 |
| 15 | Vasular complications after liver transplkantation显示文摘 | Pawlak J Grodzicki M Leowska E | 2003 | Transplant Proc2003，35，： | 1 |
| 16 | Ambulatory blood pressure monitoring and postprandial hypotension in eldrly patients with isolated systolic hypertension:in Europe (SYS- TEUR) trial investigators 显示文摘 | Grodzicki T Rajzer M Fagard R | 1998 | J Hum Hypertens1998，12，3： | 1 |
| 17 | Treatment of early hepatic artery thrombosis after liver transplantation显示文摘 | Grodzicki M Anysz-Grodzicka A Remiszewski P | | 0，，08： | 1 |
| 18 | Should a moratorium be placed on sublingual nifedipine capsules given for hypertensive emergencies and pseudoemergencies?显示文摘 | Grossman E Messerli FH Grodzicki T | 1996 | JAMA1996，276，16： | 1 |
| 19 | Meta-Analysis of Left Ventricular Hypertrophy and Sustained Arrhythmias显示文摘 | Saurav Chatterjee Chirag Bavishi Partha Sardar Vikram Agarwal Parasuram Krishnamoorthy Tomasz Grodzicki Franz H. Messerli | 2014 | The American Journal of Cardiology2014，，7： | 1 |
| 20 | Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus显示文摘 | Esdaile JM Abrahamowicz M Grodzicky T | | 0，，10： | 1 |
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