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| 1 | Follow-up of intestinal metaplasia in the stomach: When, how and why显示文摘Gastric cancer remains the second most frequent cause of cancer-related mortality in the world. Screening programs in some Asian countries are impractical in the majority of other countries worldwide. Therefore, follow-up of precancerous lesions is advisable for secondary gastric cancer prevention. Intestinal metaplasia (IM) is recognized as a precancerous lesion for gastric cancer, increasing the risk by 6-fold. IM is highly prevalent in the general population, being detected in nearly 1 of every 4 patients undergoing upper endoscopy. The IM prevalence rate is significantly higher in patients with Helicobacter pylori (H. pylori) infection, in first-degree relatives of gastric cancer patients, in smokers and it increases with patient age. IM is the 'breaking point' in the gastric carcinogenesis cascade and does not appear to regress following H. pylori eradication, although the cure of infection may slow its progression. Gastric cancer risk is higher in patients with incomplete-type IM, in those with both antral and gastric body involvement, and the risk significantly increases with IM extension over 20% of the gastric mucosa. Scheduled endoscopic control could be cost-effective in IM patients, depending on the yearly incidence of gastric cancer in IM patients, the stage of gastric cancer at diagnosis discovered at surveillance, and the cost of endoscopy. As a pragmatic behavior, yearly endoscopic control would appear justified in all IM patients with at least one of these conditions: (1) IM extension > 20%; (2) the presence of incomplete type IM; (3) first-degree relative of gastric cancer patients; and (4) smokers. In the remaining IM patients, a less intensive (2-3 years) could be proposed. | Angelo Zullo Cesare Hassan Adriana Romiti Michela Giusto Carmine Guerriero Roberto Lorenzetti Salvatore MA Campo Silverio Tomao | 2012 | World Journal of Gastrointestinal Oncology2012，4，3： | 25 |
| 2 | What Do We Really Know about Cellulose Biosynthesis in Higher Plants?显示文摘Cellulose biosynthesis is one of the most important biochemical processes in plant biology. Despite the considerable progress made during the last decade, numerous fundamental questions related to this key process in plant development are outstanding. Numerous models have been proposed through the years to explain the detailed molecular events of cellulose biosynthesis. Almost all models integrate solid experimental data with hypotheses on several of the steps involved in the process. Speculative models are most useful to stimulate further research investigations and bring new exciting ideas to the field. However, it is important to keep their hypothetical nature in mind and be aware of the risk that some undemonstrated hypotheses may progressively become admitted. In this review, we discuss the different steps required for cellulose formation and crystallization, and highlight the most important specific aspects that are supported by solid experimental data. | Gea Guerriero Johanna Fugelstad Vincent Bulone | 2010 | Journal of Integrative Plant Biology2010，52，2： | 14 |
| 3 | Guidance on opioids prescribing for the management of persistent non-cancer pain in older adults显示文摘Many older adults suffer from persistent pain but prevalence studies consistently showed high levels of untreated or under-treated pain in old population.Both persistent pain and pain under-treatment adversely affect independence and quality of life in geriatric patients.Pain management is challenging in this age-group because of the declining organ function,the presence of concurrent diseases and polypharmacy.For all the above reasons,persistent pain in the elderly should be considered a geriatric syndrome per se and effective approaches are warranted.Current guidelines and consensus statements recommend opioid therapy for older adults with moderateto-severe persistent pain or functional impairment and diminished quality of life due to pain.However clinicians and patients themselves have some concerns about opioids use.Age-related decline in organs functions and warnings about risk of addiction and drug misuse/abuse also in geriatric patients need particular attention for safe prescribing.On the basis of clinical evidence,these practical recommendations will help to improve the competence on opioid role in persistent pain management and the likelihood of a successful analgesic trial in older patients. | Fabio Guerriero | 2017 | World Journal of Clinical Cases2017，5，3： | 6 |
| 4 | Extremely low frequency electromagnetic fields stimulation modulates autoimmunity and immune responses:a possible immuno-modulatory therapeutic effect in neurodegenerative diseases显示文摘Increasing evidence shows that extremely low frequency electromagnetic fields(ELF-EMFs) stimulation is able to exert a certain action on autoimmunity and immune cells. In the past, the efficacy of pulsed ELFEMFs in alleviating the symptoms and the progression of multiple sclerosis has been supported through their action on neurotransmission and on the autoimmune mechanisms responsible for demyelination. Regarding the immune system, ELF-EMF exposure contributes to a general activation of macrophages, resulting in changes of autoimmunity and several immunological reactions, such as increased reactive oxygen species-formation, enhanced phagocytic activity and increased production of chemokines. Transcranial electromagnetic brain stimulation is a non-invasive novel technique used recently to treat different neurodegenerative disorders, in particular Alzheimer's disease. Despite its proven value, the mechanisms through which EMF brain-stimulation exerts its beneficial action on neuronal function remains unclear. Recent studies have shown that its beneficial effects may be due to a neuroprotective effect on oxidative cell damage. On the basis of in vitro and clinical studies on brain activity, modulation by ELF-EMFs could possibly counteract the aberrant pro-inflammatory responses present in neurodegenerative disorders reducing their severity and their onset. The objective of this review is to provide a systematic overview of the published literature on EMFs and outline the most promising effects of ELF-EMFs in developing treatments of neurodegenerative disorders. In this regard, we review data supporting the role of ELF-EMF in generating immune-modulatory responses, neuromodulation, and potential neuroprotective benefits. Nonetheless, we reckon that the underlying mechanisms of interaction between EMF and the immune system are still to be completely understood and need further studies at a molecular level. | Fabio Guerriero Giovanni Ricevuti | 2016 | Neural Regeneration Research2016，11，12： | 2 |
| 5 | The antiandro 2 genic effect of flu- tamide improve sutreine perfusion in women with polycystic ovarian syn- drome 显示文摘 | AJossas Guerrieros Paoleltiametal | 2002 | Ferti Steri12002，77，6： | 1 |
| 6 | Retinal circulation after carotid artery revascularization显示文摘 | Cardia G Porfido D Guerriero S | 2011 | Angiology2011，62，5： | 1 |
| 7 | Cast Reinforced Metal composites 显示文摘 | Cornie J A Guerriero R Meregalli L | 1988 | ASM international1988，，9： | 1 |
| 8 | Sporadic failure of botulinum toxin treatment in usually responsive patients with adductor spasmodic dysphonia显示文摘 | Galardi G Guerriero R Amadio S | 2001 | Neurol Sci2001，22，： | 1 |
| 9 | Operational research in the manage- ment of the operating theatre: a survey 显示文摘 | Guerriero F Guido R | 2011 | Health Care Management Science2011，14，1： | 1 |
| 10 | Structural interactions between Kisspeptin and GnRH neurons in the me- diobasal hypothalamus of the male rhesus monkey (Maeaca mulatta) as revealed by double immunofluoreseenee and eonfo-al microscopy 显示文摘 | Ramaswamy S Guerriero K A Gibbs R B | 2008 | Endocrinology2008，149，9： | 1 |
| 11 | Contribution to the study of inheritance of the character self incompatibility in apricot显示文摘 | Audergon J M Guerriero R Monteleone P | 1999 | Acta Hort1999，488，： | 1 |
| 12 | Puerperal vulvovagi- nal hematoma: sonographic findings with MRI correlation 显示文摘 | Guerriero S Ajossa S Bargellini R | 2004 | J Clin Ultrasound2004，32，8： | 1 |
| 13 | Experimental evaluation of solution approaches for the K-route maximum flow problem显示文摘 | Guerriero F | 2005 | Computers & Operations Research2005，32，9： | 1 |
| 14 | Sensitive screening tests for suspected class A carbapenemase pro- duction in species of Enterobacteriaceae显示文摘 | Pasteran F Mendez T Guerriero L | 2009 | J Clin Micro- biol2009，47，6： | 1 |
| 15 | Inhibition of TPO-induced MEK or roTOR activity induces opposite effects on the ploidy of human differentiating mcgakaryocytes 显示文摘 | GUERRIERO R PAROLINI I TESTA U | 2006 | J Cell Sci2006，119，4： | 1 |
| 16 | Passive Microwave Remote Sensing of Forests: A Model Investigation显示文摘 | Paolo Ferraszoli Leila Guerriero | 1996 | IEEE Transactions on Geoscience and Remote Sensing1996，34，2： | 1 |
| 17 | Label correcting methods to solve multicriteria shortest path problems显示文摘 | Guerriero F Musmanno R | 2001 | Journal of Optimization Theory and Applications2001，111，3： | 1 |
| 18 | Tumor markers and transvaginal ultrasonography in the diagnosis of endometrioma显示文摘 | Guerriero S Ajoss A Paoleffia M | 1996 | Obstet Gynecol1996，88，3： | 1 |
| 19 | Ldl apheresis in the treatment of non-arteritic isehaemie optic neuropathy : a 6-month follow- uo study显示文摘 | Guerriero S Giancipoli G Cantatore A | 2009 | Eve (Lond)2009，23，： | 1 |
| 20 | Contribution of power Doppler blood flow mapping to grayscale ultrasound for predicting malignancy of adnexal masses in symptomatic and asymptomatic women显示文摘 | Alcazar JL Guerriero S Laparte C | 2011 | Eur J Obstet Gynecol Reprod Biol2011，155，1： | 1 |
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