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| 1 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016，22，45： | 2 |
| 2 | Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large US community显示文摘 | Chugh SS Jui J Gunson K | 2004 | Journal of the American College of Cardiology2004，44，6： | 1 |
| 3 | Influence of intraoperative blood loss plasma levels of cytokines and endotoxin and subsequent graft live function显示文摘 | Miki C Iriyama K Gunson BK | 1997 | Arch Surg1997，132，2： | 1 |
| 4 | Urbanization, sustainability and the utilization of energy and mineral resources in China显示文摘 | Shen L Cheng S K Gunson A J | 2005 | Cities2005，22，4： | 1 |
| 5 | The impact of disease recurrence on graft survival following liver transplantation: a single centre experience显示文摘 | Ian A Rowe Kerry Webb Bridget K Gunson Naimish Mehta Sayeed Haque James Neuberger | 2008 | Transplant International2008，，5： | 1 |
| 6 | Influence of intraoperative blood loss on plasma levels of cytokines and endotoxin and subsequent graft liver function显示文摘 | Iriyama K Gunson BK | 1997 | Arch Surg1997，132，2： | 1 |
| 7 | Delayed hepatic artery thrombosis in adult orthotopic liver transplantation-a 12-year experience显示文摘 | Bhattacharjya S Gunson B K Mirza D F | 2001 | Transplantation2001，71，11： | 1 |
| 8 | Drainage culverts as hab- itat linkages and factors affecting passage by mammals显示文摘 | CLEVENGER A P CHRUSZCZ B GUNSON K | 2001 | Journal of Ap- plied Ecology2001，38，6： | 1 |
| 9 | Influence of intraoperative blood loss plasma levels of cytokines and endotoxin and subsequent graft live function显示文摘 | Miki C Iriyama K Gunson BK | 1997 | ArchSurg1997，132，2： | 1 |
| 10 | Circu- lating soluble vascular adhesion protein 1 accounts for the increased serum monoamine oxidase activity in chronic liver disease 显示文摘 | KURKIJARVI R YEQUTKIN G G GUNSON B K | 2000 | Gastroenterology2000，119，4： | 1 |
| 11 | Spatial patterns and factors influencing small vertebrate fauna road-kill aggregations显示文摘 | CLEVENGER A P CHRUSZCZ B GUNSON K E | 2003 | Biological Conservation2003，109，： | 1 |
| 12 | Influence of intraoperative blood loos on plasma levels of cytokines and endotoxin and subsequent graft live function显示文摘 | Miki C Iriyama K Gunson BK | 1997 | Arch Surg1997，132，2： | 1 |
| 13 | Influence of intraoperative blood loss on plasma levels of cytokines and endotoxin and subsequent graft liver function显示文摘 | Miki C Iriyama K Gunson BK | 1997 | Arch Surg1997，132，： | 1 |
| 14 | Perception of flavour in standardised fruit pulps with additions of acids or sugars显示文摘 | MARSH K B FRIEL E N GUNSON A | 2006 | Food Qual Prefer2006，17，5： | 1 |
| 15 | The impact of disease recurrence on graft survival following liver transplantation: A single centre experience显示文摘 | Rowe lA Webb K Gunson BK | 2008 | Transpl lnt2008，21，45： | 1 |
| 16 | Health-related quality of life following liver transplantation显示文摘 | S Bryan J Ratcliffe J. M. Neuberger A. K Burroughs B. K Gunson M. J Buxton | 1998 | Quality of Life Research1998，，2： | 1 |
| 17 | Current burden of sudden cardiac death: Multiple source surveillance versus retrospective death certi- ficate-based review in a large US community显示文摘 | Chugh SS Jui J Gunson K | 2004 | J Am Coil Cardiol2004，44，6： | 1 |
| 18 | Post-transplant lymphoproliferative disease in liver transplantation显示文摘 | Dhillon M S Rai J K Gunson B K | 2007 | Br J Radiol2007，80，953： | 1 |
| 19 | Hepaticartery thrombosis following orthotopic liver transplantation:A 10-year experience from a single centre in the UnitedKingdom显示文摘 | Silva M A Jambulingam P S Gunson B K | 2006 | Liver Transpl2006，12，1： | 1 |
| 20 | Influence of intraoperative blood loss on plasma levels of cytokines and endotoxin and subsequent graft liver function显示文摘 | Miki C Iriyama K Gunson BK | 1997 | Arch Surg1997，132，2： | 1 |
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