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| 1 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 2 | Adaptations to normal human gait on potentially slippery surfaces: The effects of awareness and prior slip experience 显示文摘 | Tamika L David J Gunter P | 2006 | Gait and Posture2006，24，2： | 1 |
| 3 | Multivariate calibration for assays in clinical chemistry using attenuated total reflection infrared spectra of human blood plasm显示文摘 | Janatsch Gunter Kruse-Jarres J D | 1989 | Anal Chem1989，61，： | 1 |
| 4 | Iron-induced injury of rat testis显示文摘 | Merker H J Vormann J Gunter T | 1996 | Andrologia1996，28，2： | 1 |
| 5 | The role of insulin-like growth factorI and its binding proteins in glucose homeostasis and type 2diabetes显示文摘 | RAJPATHAK S N GUNTER M J WYLIE-ROSETT J | 2009 | Diabetes Metab Res Rev2009，25，： | 1 |
| 6 | Increasing and decreasing tip projection in rhinoplasty显示文摘 | FRED LH GUNTER J P | 2000 | Operative Techniques in Plastic and Reconstructive Surgery2000，7，4： | 1 |
| 7 | High Proportion of Leukemic Stem Cells at Diagnosis Is Correlated with Unfavorable Prognosis in Childhood Acute Myeloid Leukemia显示文摘 | Kai-Erik Witte J?rg Ahlers Iris Sch?fer Maya André Gunter Kerst Hans-Gerhard Scheel-Walter Carl Philipp Schwarze Matthias Pfeiffer Peter Lang Rupert Handgretinger Martin Ebinger | 2011 | Pediatric Hematology-Oncology2011，，2： | 1 |
| 8 | Ureaplasma urealvticum Menin-gitis in an adult patient显示文摘 | Walter G Gunter S Stefan J | 2008 | J C lin Microbiol2008，46，： | 1 |
| 9 | A comparison of dexmedetomidine with propofol for magnetic resonance imaging sleep studies in children显示文摘 | Mahmoud M Gunter J Donnelly LF | 2009 | Anesth Analg2009，109，3： | 1 |
| 10 | The merits of the open approach in rhinoplasty显示文摘 | GUNTER J P | 1997 | Plast Reconstr Surg1997，99，： | 1 |
| 11 | Formation of 2,3 pentanedione from lactic acid over supported phosphate catalysts 显示文摘 | GUNTER G C MILLER D J JACKSON J E | 1994 | J Catal1994，148，： | 1 |
| 12 | The role of insulin- like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes显示文摘 | Rajpathak SN Gunter MJ Wylie-Rosett J | 2009 | Diabetes M etab Res Rev2009，25，： | 1 |
| 13 | The Media and Public Understanding of Biotechnology : A Survey of Scientists and Joumalists显示文摘 | Gunter B Kinderlerer J Beyleveld D | 1999 | Science Communication1999，20，4： | 1 |
| 14 | A comparison of dexme- detomidine with propofoI for magnetic resonance imaging sleep studies in children 显示文摘 | Mahmoud M Gunter J Donnelly LF | 2009 | Anesth Analg2009，109，： | 1 |
| 15 | Catalysts and supports for conversion of lactic acid to acrylic acid and 2,3-pentanedione 显示文摘 | LANGFORD R H GUNTER O C JACKSON J E | 1995 | Ind Eng Chem Res1995，34，： | 1 |
| 16 | Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey 显示文摘 | Jacques PF Rosenberg IH Rogers G Selhub J Bowman BA Gunter EW | 1999 | Am J Clin Nutr1999，69，3： | 1 |
| 17 | The decline in blood lead levels in the United States显示文摘 | Pirkle J L Brody D J Gunter E W | 1994 | JAMA1994，272，7： | 1 |
| 18 | Aquifer disposal of CO2-rich gases:Reaction design for added capacity显示文摘 | Gunter W D Perkins E H McCann T J | 1993 | Energy Conversion and Management1993，34，： | 1 |
| 19 | A comparison of dexme- detomidine with propofol for magnetic resonance imaging sleep studies in children 显示文摘 | Mahmoud M Gunter J Donnelly L | 2009 | Anesth Analg2009，109，7： | 1 |
| 20 | Lead and cadmium in indoor air and the urban environment 显示文摘 | Gunter J K Komarnieki | 2005 | Environmental Pollution2005，136，： | 1 |
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