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您的检索式：作者名="Gunter Muller"
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| 1 | Redistribution of glycolipid raft domain components induces insulin-mimetic signaling in rat adipocytes显示文摘 | Gunter Muller Christian Jung Susanne Wied | 2001 | Molecular and Celluar Biology2001，21，14： | 1 |
| 2 | Effects of Polyphenols on Brain Ageing and Alzheimer’s Disease: Focus on Mitochondria显示文摘 | Sebastian Schaffer Heike Asseburg Sabine Kuntz Walter Muller Gunter Eckert | 2012 | Molecular Neurobiology2012，，1： | 1 |
| 3 | Diabetic foot syndrome and renal function in type 1 and 2 diabetes mellitus show close association显示文摘 | Gunter Wolf Nioolle Muller Martin Busch | 2009 | Nephrol Dial Trans- plant2009，24，： | 1 |
| 4 | Take-over:multiple mechanisms of inter-adipocyte communication显示文摘Adipose tissue mass in mammals is thought to expand with an increase in both volume and total number of the adipocytes.Recent findings suggest that in normal-weight as well as obese individuals,the adipocyte number is set during adolescence prior to adulthood,whereas the subsequent increase in size predominantly drives obesity.The simultaneous existence of large and small adipocytes and their unsynchronized growth,even within the same adipose tissue depot,argues against simple filling-up of emerging adipocytes with lipids and lipid droplets(LDs).Consequently,it is tempting to speculate about signals sent by large adipocytes to order small adipocytes the take-over of the burden of lipid loading.Currently there is experimental evidence for three distinct types of inter-adipocyte signals,i.e.cell-to-cell contacts,adipokines,and other soluble factors and microvesicles.Very recently,microvesicles have been shown(i)to harbour the glycosylphosphatidylinositol-anchored(c)AMP-degrading phosphodiesterase Gce1 and 5′-nucleotidase CD73,(ii)to be released from large adipocytes,(iii)to interact with small adipocytes,and(iv)to transfer Gce1 and CD73 to plasma membranes and LDs of small adipocytes where they degrade(c)AMP.This sequence of events leads to the up-regulation of lipid storage in small adipocytes in response to the microvesicle-encoded‘take-over’signal from large adipocytes.A model is proposed for the maturation of small adipocytes driven by large ones along a gradient of those inter-adipocyte signals.Pharmacological modulation of inter-adipocyte communication and thereby adipocyte maturation may be useful for the therapy of metabolic diseases. | Gunter Muller | 2011 | Journal of Molecular Cell Biology2011，3，2： | 0 |
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