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| 1 | A Chromosome-Level Genome Assembly of Garlic (Allium sativum) Provides Insights into Genome Evolution and Allicin Biosynthesis显示文摘Garlic,an economically important vegetable,spice,and medicinal crop,produces highly enlarged bulbs and unique organosulfur compounds.Here,we report a chromosome-level genome assembly for garlic,with a total size of approximately 16.24 Gb,as well as the annotation of 57561 predicted protein-coding genes,making garlic the first Allium species with a sequenced genome.Analysis of this garlic genome assembly reveals a recent burst of transposable elements,explaining the substantial expansion of the garlic genome.We examined the evolution of certain genes associated with the biosynthesis of allicin and inulin neoseries-type fructans,and provided new insights into the biosynthesis of these two compounds.Furthermore,a large-scale transcriptome was produced to characterize the expression patterns of garlic genes in different tissues and at various growth stages of enlarged bulbs.The reference genome and large-scale transcriptome data generated in this study provide valuable new resources for research on garlic biology and breeding. | Xiudong Sun Siyuan Zhu Ningyang Li Yi Cheng Jing Zhao Xuguang Qiao Li Lu Shiqi Liu Yanzhou Wang Chan Liu Benping Li Wu Guo Shuang Gao Zemao Yang Fu Li Zheng Zeng Qing Tang Yupeng Pan Mengjiao Guan Jian Zhao Xiaomi ng Lu Huanwe n Meng Zhenlin Han Chun she ng Gao Wenkai Jiang Xing Zhao Shilin Tian Jianguang Su Zhihui Cheng Touming Liu | 2020 | Molecular Plant2020，13，9： | 14 |
| 2 | Finite groups with systems of Σ-embedded subgroups显示文摘In recent years,a series of papers about cover-avoiding property of subgroups appeared and all the studies were connected with chief factors of a finite group.However,about the cover-avoiding property of subgroups for non-chief factor,there is no study up to now.The purpose of this paper is to build the theory.Let A be a subgroup of a finite group G and Σ:G0≤G1≤…≤Gn some subgroup series of G.Suppose that for each pair(K,H) such that K is a maximal subgroup of H and G i 1 K < H G i for some i,either A ∩ H = A ∩ K or AH = AK.Then we say that A is Σ-embedded in G.In this paper,we study the finite groups with given systems of Σ-embedded subgroups.The basic properties of Σ-embedded subgroups are established and some new characterizations of some classes of finite groups are given and some known results are generalized. | GUO WenBin SKIBA Alexander N | 2011 | Science China Mathematics2011，54，9： | 14 |
| 3 | Effects of reclaimed water irrigation and nitrogen fertilization on the chemical properties and microbial community of soil显示文摘The ecological effect of reclaimed water irrigation and fertilizer application on the soil environment is receiving more attention.Soil microbial activity and nitrogen(N)levels are important indicators of the effect of reclaimed water irrigation on environment.This study evaluated soil physicochemical properties and microbial community structure in soils irrigated with reclaimed water and receiving varied amounts of N fertilizer.The results indicated that the reclaimed water irrigation increased soil electrical conductivity(EC)and soil water content(SWC).The N treatment has highly significant effect on the ACE,Chao,Shannon(H)and Coverage indices.Based on a 16S ribosomal RNA(16S rRNA)sequence analysis,the Proteobacteria,Gemmatimonadetes and Bacteroidetes were more abundant in soil irrigated with reclaimed water than in soil irrigated with clean water.Stronger clustering of microbial communities using either clean or reclaimed water for irrigation indicated that the type of irrigation water may have a greater influence on the structure of soil microbial community than N fertilizer treatment.Based on a canonical correspondence analysis(CCA)between the species of soil microbes and the chemical properties of the soil,which indicated that nitrate N(NO_3~–-N)and total phosphorus(TP)had significant impact on abundance of Verrucomicrobia and Gemmatimonadetes,meanwhile the p H and organic matter(OM)had impact on abundance of Firmicutes and Actinobacteria significantly.It was beneficial to the improvement of soil bacterial activity and fertility under 120 mg kg^(–1) N with reclaimed water irrigation. | GUO Wei Mathias N Andersen QI Xue-bin LI Ping LI Zhong-yang FAN Xiang-yang ZHOU Yuan | 2017 | Journal of Integrative Agriculture2017，16，3： | 7 |
| 4 | Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel,flavopiridol,and 5-fluorouracil显示文摘瞄准:有 docetaxel, flavopiridol,或 5 氟尿嘧啶(5-FU ) 的稳固的肿瘤的临床的治疗经常遇到不受欢迎的副作用和药抵抗。在 modulating chemosensitivity 并且更好与 docetaxel, flavopiridol,或 5-FU 评估联合治疗的潜在的角色的目的理解他们怎么可能临床上被使用的这研究。方法:HCT116 结肠癌房间在几不同行政时间表在试管内与 docetaxel, flavopiridol,和 5-FU 被对待,顺序或同时。房间幸存被 MTT 试金测量。caspase-3 的活动被 caspase-3 试金决定,软琼脂殖民地试金被用来在软琼脂测试 HCT116 房间的菌落形成。我们也建立了异种皮移植模型扩大在试管内观察到一个在活体内系统。结果:当人的结肠癌 HCT116 房间为 flavopiridol 为另一 24 h 为 24 h 和 5-FU 跟随的 1 h 与 docetaxel 被对待时,最大的细胞毒性被发现。这顺序的联合治疗不仅与另外的联合治疗相比更强烈禁止肿瘤细胞生长而且显著地在软琼脂减少菌落形成并且扩充 HCT116 细胞的 apoptosis。docetaxel 定序以后由 flavopiridol 跟随了 1 h,以后在异种皮移植模型由 5-FU 跟随了 24 h,也导致了推迟的肿瘤生长和更高的幸存率。结论:当把 docetaxel 与 flavopiridol 和 5-FU 相结合时,这些结果强调一张行政时间表的重要性,提供对它在临床的试用的发展的基本原理解释。 | Jun GUO An-wu ZHOU Yu-cai FW Udit N VERMA Debu TRIPATHY Eugene P FRENKEL Carlos R BECERRA | 2006 | Acta Pharmacologica Sinica2006，27，10： | 4 |
| 5 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 6 | A novel integrated non-targeted metabolomic analysis reveals significant metabolite variations between different lettuce (Lactuca sativa. L) varieties显示文摘Lettuce is an important leafy vegetable that represents a significant dietary source of antioxidants and bioactive compounds.However,the levels of metabolites in different lettuce cultivars are poorly characterized.In this study,we used combined GC×GC-TOF/MS and UPLC-IMS-QTOF/MS to detect and relatively quantify metabolites in 30 lettuce cultivars representing large genetic diversity.Comparison with online databases,the published literature,standards as well using collision cross-section values enabled putative identification of 171 metabolites.Sixteen of these 171 metabolites(including phenolic acid derivatives,glycosylated flavonoids,and one iridoid)were present at significantly different levels in leaf and head type lettuces,which suggested the significant metabolomic variations between the leaf and head types of lettuce are related to secondary metabolism.A combination of the results and metabolic network analysis techniques suggested that leaf and head type lettuces contain not only different levels of metabolites but also have significant variations in the corresponding associated metabolic networks.The novel lettuce metabolite library and novel non-targeted metabolomics strategy devised in this study could be used to further characterize metabolic variations between lettuce cultivars or other plants.Moreover,the findings of this study provide important insight into metabolic adaptations due to natural and human selection,which could stimulate further research to potentially improve lettuce quality,yield,and nutritional value. | Xiao Yang Shiwei Wei Bin Liu Doudou Guo Bangxiao Zheng Lei Feng Yumin Liu Francisco A.Tomás-Barberán Lijun Luo Danfeng Huang | 2018 | Horticulture Research2018，5，1： | 3 |
| 7 | Active DNA or active histone triggering the production of antinuclear antibodies: inducing the generation of kidney iniury in mice显示文摘 | Wu H S Ma A N Guo L | 2000 | J Allergy Clin Immunol2000，105，1： | 2 |
| 8 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010，，5： | 2 |
| 9 | Adsorption study of copper(Ⅱ) by chemically modified orange peel显示文摘 | FENG N GUO X LIANG S | 2009 | J Hazard Mater2009，164，： | 1 |
| 10 | Enhanced inulinase production in solid state fermentation by a mutant of the marine yeast Pichia guillierrnondii using surface response methodology and inulin hydrolysis 显示文摘 | Guo N Gong F Chi Z | 2009 | Microbiol Biotechnol2009，36，4： | 1 |
| 11 | Distribution and viral load of eight ancogenic types of human papillomavirus (HPV) and HPV 16 integration status in cervical intraepithelial neoplasia and carcinoma显示文摘 | Guo M Sneige N Silva EG | 2007 | Mod Pathol2007，20，2： | 1 |
| 12 | Study on the corrosion re- sistance of phytic acid conversion coating for magnesiu mal- loys 显示文摘 | Liu J R Guo Y N Huang W D | 2006 | Surface and Coatings Technology2006，201，34： | 1 |
| 13 | Kinetic and thermodynamic studies on biosorption of Cu (II) by chemically modified orange peel 显示文摘 | Liang S Guo X Y Feng N C | 2009 | Trans Nonferrous Met Soc China2009，19，： | 1 |
| 14 | Realistic and efficient rendering of free-form knitwear显示文摘 | Zhong H Xu Y Q Guo B N | 2001 | The Journal of Visualization and Computer Animation2001，12，1： | 1 |
| 15 | Nitrogen bonding structure in carbon nitride thin films studied by soft x-ray spectroscopy 显示文摘 | Hellgren N Guo J Sathe C | 2001 | Appl Phys Lett2001，79，： | 1 |
| 16 | Angiotensinogen gene variation in a population case-control study of preeclampsia/eclaspsia in Australians and Chinese显示文摘 | GUO G WILTON A N FU Y | 1997 | Electrophoresis1997，18，9： | 1 |
| 17 | Comparison between methods for glutathione reductase activity assays in maize seedlings显示文摘 | GUO L H CHEN S N GONG M | 1999 | Journal of Yunnan University1999，21，5： | 1 |
| 18 | A H∞ control method of the bullwhip effect for a class of supply chain systems显示文摘 | Huang X Y Yan N N Guo H F | 2007 | Int J of Production Research2007，45，7： | 1 |
| 19 | Comparison of methods for glutathione reductase activity assays in maize seedlings显示文摘 | Guo L H Chen S N Gong M | 1999 | Journal of Yunnan University (Natural Sciences Edition)1999，21，5： | 1 |
| 20 | Study on the machining mechanism of WEDM with ultrasonic vibration of the wire显示文摘 | GUO Z N LEE T C | 1997 | Journal of Materials Processing Technology1997，69，13： | 1 |
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