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您的检索式：作者名="Guo Shaoxia"
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| 1 | Pretreatment with Danhong injection protects the brain against ischemia-reperfusion injury显示文摘Danhong injection(DHI),a Chinese Materia Medica standardized product extracted from Radix Salviae miltiorrhizae and Flos Carthami tinctorii,is widely used in China for treating acute ischemic stroke.In the present study,we explored the neuroprotective efficacy of DHI in a rat model of temporary middle cerebral artery occlusion,and evaluated the potential mechanisms underlying its effects.Pretreatment with DHI(0.9 and 1.8 mL/kg)resulted in a significantly smaller infarct volume and better neurological scores than pretreatment with saline.Furthermore,DHI significantly reduced the permeability of the blood-brain barrier,increased occludin protein expression and decreased neutrophil infiltration,as well as profoundly suppressing the upregulation of matrix metallopeptidase-9 expression seen in rats that had received vehicle.Matrix metallopeptidase-2 expression was not affected by ischemia or DHI.Moreover,DHI(1.8 mL/kg)administered 3 hours after the onset of ischemia also improved neurological scores and reduced infarct size.Our results indicate that the neuroprotective efficacy of DHI in a rat model of cerebral ischemia-reperfusion injury is mediated by a protective effect on the blood-brain barrier and the reversal of neutrophil infiltration. | Shaoxia Wang Hong Guo Xumei Wang Lijuan Chai Limin Hu Tao Zhao Buchang Zhao Xiaoxu Tan Feifei Jia | 2014 | Neural Regeneration Research2014，9，15： | 12 |
| 2 | Effects of media and nutrient levels on seedling growth and flower of Cymbidium hybridum显示文摘 | Zhao Jiuzhou Zhou Chunling Guo Shaoxia | 2001 | Forestry Studies in China2001，9，3： | 1 |
| 3 | Carbon layer-coated ordered mesoporous silica supported Co-based catalysts for higher alcohol synthesis:The role of carbon source显示文摘Surface chemical properties of supports have an important influence on active sites and their catalytic behavio r.Here,we fabricated a series of cobalt-based catalysts supported by carbon layer-coated ordered mesoporous silica(OMS) composites for higher alcohol synthesis(HAS).The carbon layers were derived from different sources and uniformly coated on the porous surface of OMS.Combined with the characterization results of carbonized catalysts,it is demonstrated that the carbon layer-coated supports significantly enhanced the metal dispersion and increased the ratio of Co2+ to Co0 sites,which further increased the CO conversion and alcohols selectivity.Moreover,it is found that the catalytic activity changed in line with the amount of defects and surface oxygenic groups of carbon layers,which re sulted from the different carbon sources.The highest space time yield of C2+OH was 27.5 mmol gcat-1h-1)obtained by the catalyst coated with glucose-derived carbon layer.But the carbon source is not the key factor influencing the distribution of Co-Co2+ dual sites and shows little effect on selectivity in HAS.These results may guide for further design of carbon supported catalysts. | Siqi Fan Yue Wang Zhuoshi Li Zhuang Zeng Shaoxia Guo Shouying Huang Xinbin Ma | 2020 | Chinese Chemical Letters2020，31，2： | 0 |
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