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| 1 | Preparation process of bio-oil and bio-asphalt,their performance,and the application of bio-asphalt:A comprehensive review显示文摘The objective of this paper is to establish the state of knowledge on fast pyrolysis of bio-oil and bio-asphalt binder and to facilitate efforts in improving the overall perform ance of bioasphalt and maximizing its road application.On the basis of reviewing the relevant literature recently,the fast pyrolysis(FasP) preparation process of bio-oil and its main properties,the preparation process of bio-asphalt and its performance and the application of bio-asphalt have been summarized.Due to the variations in raw materials,the adopted methods of FasP to prepare bio-oil could be different,and the properties of bio-oil from different sources are also different.At present,the plant-based bio-oil(mainly derived from wood waste and sawdust) has been widely used to prepare the bio-asphalt.Research on the low-temperature flexibility,high-temperature rheology,workability and other performance of biological asphalt showed that the workability and high-temperature performance of most asphalt are improved after adding bio-oil.However,the low-temperature performance is found to relatively reduce.Also,with regards to its application as a rejuvenator,bio-oil can considerably rejuvenate the aged asphalt’s mixture performance.By far,most of research on bio-asphalt is still focused on the performance of bio-asphalt binder in the laboratory;its application in practical road engineering is still to be examined.This review also provides an outlook for the future,for example,establishing an integrated preparation process from bio-oil to bio-asphalt,and evaluating the properties of bioasphalt by new standards. | Hainian Wang Ziye Ma Xi Chen Mohd Rosli Mohd Hasan | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，2： | 5 |
| 2 | 6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinase pathway显示文摘6-Gingerol,a pungent ingredient of ginger,has been reported to possess anti-inflammatory and antioxidant activities,but the effect of 6-gingerol on pressure overload-induced cardiac remodeling remains inconclusive.In this study,we investigated the effect of 6-gingerol on cardiac remodeling in in vivo and in vitro models,and to clarify the underlying mechanisms.C57BL/6 mice were subjected to transverse aortic constriction(TAC),and treated with 6-gingerol(20 mg/kg,ig)three times a week(1 week in advance and continued until the end of the experiment).Four weeks after TAC surgery,the mice were subjected to echocardiography,and then sacrificed to harvest the hearts for analysis.For in vitro study,neonatal rat cardiomyocytes and cardiac fibroblasts were used to validate the protective effects of 6-gingerol in response to phenylephrine(PE)and transforming growth factor-β(TGF-β)challenge.We showed that 6-gingerol administration protected against pressure overload-induced cardiac hypertrophy,fibrosis,inflammation,and dysfunction in TAC mice.In the in vitro study,we showed that treatment with 6-gingerol(20μM)blocked PE-induced-cardiomyocyte hypertrophy and TGF-β-induced cardiac fibroblast activation.Furthermore,6-gingerol treatment significantly decreased mitogen-activated protein kinase p38(p38)phosphorylation in response to pressure overload in vivo and extracellular stimuli in vitro,which was upregulated in the absence of 6-gingerol treatment.Moreover,transfection with mitogen-activated protein kinase kinase 6 expressing adenoviruses(Ad-MKK6),which specifically activated p38,abolished the protective effects of 6-gingerol in both in vitro and in vivo models.In conclusion,6-gingerol improves cardiac function and alleviates cardiac remodeling induced by pressure overload in a p38-dependent manner.The present study demonstrates that 6-gingerol is a promising agent for the intervention of pathological cardiac remodeling. | Shu-qing Ma Zhen Guo Fang-yuan Liu Shahzad-Gul Hasan Dan Yang Nan Tang Peng An Ming-yu Wang Hai-ming Wu Zheng Yang Di Fan Qi-zhu Tang | 2021 | Acta Pharmacologica Sinica2021，42，10： | 2 |
| 3 | Impaired long-term de- pression in schizophrenia: a cathodal tDCS pilot study 显示文摘 | Hasan A Nitsche MA Herrmann M | 2012 | Brain Stimulation2012，5，4： | 1 |
| 4 | Longevity of band and loop space maintainers using glass ionomer cement: a prospective study 显示文摘 | Sasa IS Hasan AA Qudeimat MA | 2009 | Eur Arch Paediatr Dent2009，10，1： | 1 |
| 5 | Clinical pharmacy and pharmaceutical care: a need to homogenize the concepts显示文摘 | Ahmed SI Hasan SS Hassali MA | 2010 | Am J Pharm Educ2010，74，10： | 1 |
| 6 | Abnormal bihemispheric responses in schizophrenia patients following cathodal transcranial direct stimulation显示文摘 | Hasan A Aborowa R Nitsche MA | 2012 | Eur Arch Psychiatry Clin Neurosci2012，262，5： | 1 |
| 7 | Determination of nickel, copper,zinc and lead in human scalp hair in syrian occupationally exposed workers by total reflection X - ray fluorescence显示文摘 | Khuder A Bakir MA Hasan R | 2008 | Envi- ronmental Monitoring and Assessment2008，143，： | 1 |
| 8 | Isolation of Vibrio cholerae 0139 Bengal from water in Bangladesh显示文摘 | Islam MS Hasan MK Miah MA | 1993 | Lancet1993，342，8868： | 1 |
| 9 | Automatic evaluation of cardiac hypertrophy using cardiothoraeie area ratio in chest radiograph images 显示文摘 | Hasan MA Lee SL Kim DH | 2012 | Comput Methods Programs Biomed2012，105，2： | 1 |
| 10 | Two flavonol triglycosides from flowers of lndigofera hebepetala 显示文摘 | Hasan A Ahmad I Khan MA | 1996 | Phytochemistry1996，43，： | 1 |
| 11 | Longevity of band and loop space maintainers using glass ionomer cement: a prospective study 显示文摘 | Sasa IS Hasan AA Qudeimat MA | 2009 | Eur Arch Paediatr Dent2009，10，1： | 1 |
| 12 | A Modified Massey-Omura Parallel Multiplier for a Class of Finite Fields显示文摘 | HASAN MA WANG MZ BHARGAVA VK | 1993 | IEEE Transactions on Computers1993，42，11： | 1 |
| 13 | Low Complexity Word-Level Sequential Normal Basis Multipliers显示文摘 | REYHANI - MASOLEH A HASAN MA | 2005 | IEEE transactions on computers2005，54，2： | 1 |
| 14 | Irritable bowel syndrome in a rural community in Bangladesh: prevalence, symptoms pattern, and healthcare seeking behavior 显示文摘 | Masud MA Hasan M Khan AK | 2001 | Am J Gastroenterol2001，96，5： | 1 |
| 15 | neo-Clerodane Diterpenoids from Barringtonia racemosa 显示文摘 | Hasan CM Khan S Rashid MA | 2000 | Journal of Natural Products2000，63，3： | 1 |
| 16 | Influence of Substrate and Annealing Temperatures on Optical Properties of RF-sputtered TiO, Thin Films显示文摘 | Hasan MM Haseeb AS MA Saidur R Masjuki HH Hamdi M | 2010 | Optical Materials2010，32，： | 1 |
| 17 | Longevity of band and loop space maintainers using glass ionomer cement:a prospectivestudy显示文摘 | Sasa IS Hasan AA Qudeimat MA | 2009 | Eur Arch Paediatr Dent2009，10，1： | 1 |
| 18 | Effects of extremely low frequency magnetic field on fertility of adult male and female rats显示文摘 | A1-Akhras MA Elbetieha A Hasan MK | 2001 | Bioelectromagnetics2001，22，5： | 1 |
| 19 | Dysfunctional long- term potentiation-like plasticity in schizophrenia revealed by transcranial direct current stimulation显示文摘 | Hasan A Nitsche MA Rein B | 2011 | Behavioral Brain Reserch2011，224，1： | 1 |
| 20 | Clinical pharmacy and pharmaceutical care:a need to homogenize the concepts 显示文摘 | Ahmed SI Hasan SS Hassali MA | 2010 | Am J Pharm Educ2010，74，10： | 1 |
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