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    题名 作者 年代 出处 被引量
1Are the reductions in triacylglycerol and insulin levels after exercise related? 显示文摘Gill J M Herd S L Tsetsenis N V 2002Clin Sci (Lond)2002,102,:1
2Apoptosis and necrosis: detection, discrimination and phagoeytosis 显示文摘Krysko D V Berghe T V D'Herde K 2008Methods2008,44,3:1
3Apoptosis and necrosis: Deteclion, discrimination and phagocytosis 显示文摘Dmitri V Krysko 'Fore Vanden Berghe Katharina D' Herde 2008Methods2008,44,3:1
4Effects of a brisk walk onlipoprotein lipase activity and plasma triglyceride concentrations in the fasted and postprandial states显示文摘 Herd SL Vora V 2003Eur J Appl Physiol2003,89,2:1
5A randomized controlled trial of platelet activity before and after cessation of clopidogrel therapy in patients with stable cardiovascular disease 显示文摘FORD I SCOTY N W HERD V 2014J Am Coll Cardiol2014,63,3:1
6Estimating pension liabilities : A methodological framework 显示文摘NOORD V HERD P R 1994OECD Econ Stud1994,,25:1
7每日与每周局部应用5%氟尿嘧啶(Efudix~霜)治疗光化性角化病的随机试验显示文摘Background: Topical 5-fluorouracil (5-FU) cream is widely used in the treatment of actinic keratoses (AKs) but the optimumtreatment regimen that provides efficacywhileminimizing side-effects remains unclear. Objectives A randomized trial to compare the efficacy and side-effects of daily vs. weekly application of 5%5-FU in the treatment of AKs of the scalp and face. Patients/methods Twenty patients were recruited and randomized to two groups. Group 1 (13 patients) appl ied 5%5-FU twice daily for 3 weeks, group 2 (seven patients) applied 5%5-FU twice daily for 1 day per week for 12 weeks. Patients were reviewed at weeks 3, 12, 24 and 52. At each review a lesion count and lesion map were completed and p atients were asked to score efficacy and inflammation. Results At week 0 the med ian lesion count was the same in both groups, 17.5 lesions. At 12 weeks the medi an lesion count in group 1 had fallen to 0 where it remained for the duration of follow-up. In group 2 the median lesion count fell to 6 at 12 weeks, 5.5 at 24 weeks and was 3 at 52 weeks. The difference in the lesion count was significant at all time points after week 0: P < 0.05 at weeks 12 and 52, and P < 0.01 at w eek 24. The mean inflammation score was higher in patients clear of AKs at 12 we eks compared with those who had not cleared, 3.8 compared with 1.9. This differe nce was statistically significant (P < 0.05) suggesting that inflammation is nec essary for efficacy. Conclusions We conclude that daily application of 5%5-FU cream is more effective than weekly application at clearing AKs from the scalp a nd face. Our results also suggest that inflammation is likely to be required to achieve a therapeutic effect.Jury C.S Ramraka-Jones V.S Gudi V Herd R.M 罗素菊 2006世界核心医学期刊文摘(皮肤病学分册)2006,0,1:0
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