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30篇 您的检索式:作者名="HERZER M"
    题名 作者 年代 出处 被引量
1Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma-a rationale for a molecular targeting strategy?显示文摘AIM: To define the (co-)expression pattern of target receptor-tyrosine-kinases (RTK) in human gastric adenocarcinoma. METHODS: The (co-)expression pattern of VEGFR1-3,PDGFRα/b and EGFR1 was analyzed by RT-PCR in 51 human gastric adenocarcinomas. In addition,IHC staining was applied for confirmation of expression and analysis of RTK localisation. RESULTS: The majority of samples revealed a VEGFR1 (98%),VEGFR2 (80%),VEGFR3 (67%),PDGFRα (82%) and PDGFRβ(82%) expression,whereas only 62% exhibited an EGFR1 expression. 78% of cancers expressed at least four out of six RTKs. While VEGFR1-3 and PDGFRα revealed a predominantly cytoplasmatic staining in tumor cells,accompanied by an additional nuclear staining for VEGFR3 ,EGFR1 was almost exclusively detected on the membrane of tumor cells. PDGFRβ was restricted to stromal pericytes,which also depicted a PDGFRα expression.receptor-tyrosine-kinases coexpression in gastric adenocarcinoma and might therefore encourage an application of multiple-target RTK-inhibitors within a combination therapy.Daniel Drescher Markus Moehler Ines Gockel Kirsten Frerichs Annett Müller Friedrich Dünschede Thomas Borschitz Stefan Biesterfeld Martin Holtmann Thomas Wehler Andreas Teufel Kerstin Herzer Thomas Fischer Martin R Berger Theodor Junginger Peter R Galle Carl C Schimanski 2007World Journal of Gastroenterology2007,13,26:4
2Phylogenetic distribution of branched RNA-linked multicopy single-stranded DNA among natural isolates of Escherichia coli 显示文摘Herzer P J Inouye S Inouye M 1990J Bacteriol1990,172,11:1
3Perceived social support and its association with obesity--specific health--related quality of life显示文摘Herzer M Zeller M H Rausch J R 2011J Dev Behav Pediatr2011,32,3:1
4A convergence analysis of the Landweber iteration for nonlinear ill-posed problems显示文摘HANKE M EUBAUER A HERZER O 1995Inverse Problems1995,72,:1
5The effect of coherent uniaxial anisotropies on the grain size dependence of coercivity in naonocrystalline soft magnetic alloys显示文摘Suzuki K Herzer G Cadogan J M 1998J Mag Mag Mater1998,,:1
6Phylogenetic distribution of single-stranded DNA among natu- ral isolates of Escherichia coli 显示文摘Herzer PJ Inouye S Inouye M branched RNA-linked multicopy 1990J Bacteriol1990,172,11:1
7Structur- al anisotropy of amorphous alloys with creep induced mag- netic anisotropy显示文摘OHNUMA M HERZER G KOZIKOWSKI P ET AL 2011Acta Materialia2011,60,3:1
8The effect of coherent uniaxial anisotropies on the grain size dependence of coercivity in naonocrystalline soft magnetic alloys显示文摘Suzuki K Herzer G Cadogan J M 1998J Mag Mag Mater1998,177,:1
9The Effect of Coherent Uniaxial Anisotropies on the Grain-size Dependence of Coercivity in Nanocrystalline Soft Magnetic Alloys 显示文摘Suzuki K Herzer G Cadogan J M 1998J Magn Magn Mater1998,,:1
10Family functioning in the context of pediatric chronic conditions 显示文摘Herzer M Godiwala N Hommel KA 2010J Dev Behav Pediatr2010,31,1:1
11Round table discussion: Present and future applications of nanocrystalline magnetic materials 显示文摘Herzer G Vazquez M Knobel M 2005Journal of Magnetism and Magnetic Materials2005,294,:1
12A practical framework for patient care teams to prospec- tively identify and mitigate clinical hazards显示文摘Herzer K R Rodriguez-Paz J M Doyle P A 2009Jt Comm J Qual Patient Saf2009,35,2:1
13Family functioning in the context of pediatric chronic conditions 显示文摘Herzer M Godiwala N Hommel KA 2010J Dev Behav Pediatr2010,31,1:1
14Family functio-ning in the context of pediatric chronic conditions显示文摘Herzer M Godiwala N Hommel KA 2010J DevBehav Pediatr2010,31,1:1
15Phylogenetic distribution of branched RNA-linked multicopy single-stranded DNA among natural isolates of Escherichia coil 显示文摘Herzer P J Inouye S Inouye M 1990J Bacteriol1990,172,:1
16Psychological screen- ing in adolescents with type 1 diabetes predicts outcomes one year later显示文摘Hilliard ME Herzer M Dolan LM 2011Diabetes Res Clin Pratt2011,94,1:1
17Family func-tioning in the context of pediatric chronic conditions 显示文摘Herzer M Godiwala N Hommel KA 2010J Dev Behav Pediatr2010,31,1:1
18Phylogenetic distribution of branched RNA-linked multicopy single- stranded DNA among natural isolates of Escherichia coli 显示文摘Herzer P J Inouye S Inouye M 1990J Bacteriol1990,172,11:1
19Structural anisotropy of amorphous alloys with creep induced mag neticanisotropy显示文摘Ohnuma M Herzer G Kozikowski P 2011Acta Materialia2011,60,3:1
20Family functioning in the context of pediatric chronic conditions显示文摘Herzer M Godiwala N Hommel KA 2010J Dev Behav Pediatr2010,31,1:1
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