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| 1 | No difference in mortality among ALPPS,two-staged hepatectomy,and portal vein embolization/ligation:A systematic review by updated traditional and network meta-analyses显示文摘Background:There is an ongoing debate on the feasibility,safety,and oncological efficacy of the associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)technique.The aim of this study was to compare ALPPS,two-staged hepatectomy(TSH),and portal vein embolization(PVE)/ligation(PVL)using updated traditional meta-analysis and network meta-analysis(NMA).Data sources:Electronic databases were used in a systematic literature search.Updated traditional metaanalysis and NMA were performed and compared.Mortality and major morbidity were selected as primary outcomes.Results:Nineteen studies including 1200 patients were selected from the pool of 436 studies.Of these patients,315(31%)and 702(69%)underwent ALPPS and portal vein occlusion(PVO),respectively.Ninetyday mortality based on updated traditional meta-analysis,subgroup analysis of the randomized controlled trials(RCTs),and both Bayesian and frequentist NMA did not demonstrate significant differences between the ALPPS cohort and the PVE,PVL,and TSH cohorts.Moreover,analysis of RCTs did not demonstrate significant differences of major morbidity between the ALPPS and PVO cohorts.The ALPPS cohort demonstrated significantly more favorable outcomes in hypertrophy parameters,time to operation,definitive hepatectomy,and R0 margins rates compared with the PVO cohort.In contrast,1-year disease-free survival was significantly higher in the PVO cohort compared to the ALPPS cohort.Conclusions:This study is the first to use updated traditional meta-analysis and both Bayesian and frequentist NMA and demonstrated no significant differences in 90-day mortality between the ALPPS and other hepatic hypertrophy approaches.Furthermore,two high quality RCTs including 147 patients demonstrated no significant differences in major morbidity between the ALPPS and PVO cohorts. | Paschalis Gavriilidis Robert P Sutcliffe Keith J Roberts Madhava Pai Duncan Spalding Nagy Habib Long R Jiao Mikael H Sodergren | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，5： | 6 |
| 2 | Fluvastatin decreses soluble thrombomodulin in cadiac transplant recipients显示文摘 | Ambrosi P Aillaud MF Habib G | 2000 | Thromb Haemost2000，83，1： | 1 |
| 3 | Roles of a ribosome-binding site and mRNA secondary structure in differential expression of Shiga toxin genes显示文摘 | Habib N F Jackson M P | 1993 | Baeteriol1993，175，： | 1 |
| 4 | The combination of intravitreal triamcinolone and phacoemulsification surgery in patients with diabeticfoveal oedema and cataract 显示文摘 | HABIB M S CANNON P S STEEL D H | 2005 | BMC Ophthalmol2005，5，： | 1 |
| 5 | Opposite clear corneal incisions on the steep meridian in phacoemulsification:early effects on the cornea显示文摘 | Tadros A Habib M Tejwani D von Lany H Thomas P | 2004 | J Cataract Refract Surg2004，30，2： | 1 |
| 6 | Consensus guide- lines for the management of postoperative nausea and vomiting显示文摘 | GAN T J DIEMUNSCH P HABIB A S | 2014 | Anesth Analg2014，118，10： | 1 |
| 7 | The use of a re-entry catheter in recanalization of chronic inflow occlusions of the common iliac artery显示文摘 | Ramjas G Thurley P Habib S | 2008 | Cardiovasc Intervent Radiol2008，31，： | 1 |
| 8 | Some Problems about Linear Arboricity显示文摘 | Habib M Péroche B | 1982 | Discrete Mathematics1982，41，2： | 1 |
| 9 | The statins: new properties 显示文摘 | Ambrosi P Villani P Habib G | 2003 | Therapie2003，58，1： | 1 |
| 10 | Fluvastatin decreases soluble thrombomodulin in cardiac transplant recipients显示文摘 | Aillaud MF Habib G | 2000 | Thromb Haemost2000，83，： | 1 |
| 11 | The Malpasset clam failure 显示文摘 | Habib P | 1987 | Engineering Geology1987，24，： | 1 |
| 12 | Pharmacotherapies in the management of obsessive-compulsive disorder显示文摘 | Blier P Habib R Flament MF | 2006 | Can J Psychiatry2006，51，： | 1 |
| 13 | Guidelines on the pre-vention, diagnosis,and treatment of infective endocarditis(new version 2009) : the Task Force on the Prevention, Diag-nosis, and Treatment of Infective Endocarditis of the Europe-an Society of Cardiology (ESC) 显示文摘 | Habib G Hoen B Tornos P | 2009 | Eur Heart J2009，30，19： | 1 |
| 14 | Consensus guide- lines for the management of postoperative nausea and vomiting显示文摘 | Gan T J Diemunsch P Habib AS | 2014 | Anesth Analg2014，118，1： | 1 |
| 15 | Cyclosporine in treatment of idiopathic nephrosis显示文摘 | Niaudet P Habib R | 1994 | J Am Soc Nephrol1994，5，4： | 1 |
| 16 | Consen- sus guidelines for the management of postopera- tive nausea and vomiting 显示文摘 | Gan T J Diemunsch P Habib AS | 2014 | Anesth Analg2014，118，1： | 1 |
| 17 | Cyclosporine in the treatment of idiopathic nephrosis显示文摘 | Niaudet P Habib R | 1994 | J Am Soc Nephrol1994，，5： | 1 |
| 18 | Adult's heart failure 显示文摘 | Ambrosi P Habib G | 2014 | Revue Prat2014，64，4： | 1 |
| 19 | Consensus guidelines |or the management of postoperative nausea and vomiling显示文摘 | Gan TJ Diemunsch P Habib AS | 2014 | Anesth Analg2014，118，： | 1 |
| 20 | Methylprednisolone pulse therapy in the treatment of severe forms of Schonlein - Henoch purpura nephritis 显示文摘 | Niaudet P Habib R | 1998 | Pediatr Nephrol1998，12，： | 1 |
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