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| 1 | Transcatheter aortic valve replacement and stroke: a comprehensive review显示文摘Transcatheter 大动脉的阀门培植(TAVR ) 与严重大动脉的狭窄和高外科的风险为病人作为一种其他的、很快演变的治疗选择出现了。此后摸破坏复杂并发症主要在 periprocedural 和 30 天的时期追随者 TAVR 正在被限制,与更低、相对经常的频率。早击在过程期间主要由于碎片 embolization,而以后的事件与耐心的特定的因素被联系。尽管临床的击的率常常与起始的 TAVR 经验相比一直在减少,有 MRI 的现代 neuro 成像建议新 ischemic 损害 post-TAVR 是几乎通用的。后者的影响大部分是未知的。然而,他们似乎在 neurocognitive 功能与减小相关。因为 TAVR 被设置扩展它的指示降低外科风险的病人,摸预防在期间并且在 TAVR 以后降临到首要的重要性。基于临床并且 pathophysiological 证据,研究的三根线活跃地向这个方向被采用:在有到有钙化的大动脉的拱门的还原剂操作和接触的一个目的阀门和本国的阀门, antithrombotic 治疗,和插子的保护设备的改进。小心的耐心的选择,过程的设计,和尊重这张易碎的人口的流血风险的定制的 antithrombotic 策略对击追随者 TAVR 组成主要防卫。 | Periklis A Davlouros Virginia C Mplani Ioanna Koniari Grigorios Tsigkas George Hahalis | 2018 | Journal of Geriatric Cardiology2018，15，1： | 7 |
| 2 | TAVR in 2017-What we know? What to expect?显示文摘 | Panaglota Kourkoveli Konstantinos Spargias George Hahalis | 2018 | Journal of Geriatric Cardiology2018，15，1： | 4 |
| 3 | The role of echocardiography and CT angiography in transcatheter aortic valve implantation patients显示文摘transcatheter 大动脉的阀门培植(TAVI ) 在于在有严重大动脉的狭窄的病人的其他的治疗。Multimodality 成像使用 transthoracic echocardiography (TTE ) 或 transesophageal echocardiography (脚趾) 和 multislice CT (MSCT ) 为外科手术前的管理组成奠基石技术,仙子程序的指导,列在后面在上面并且可能的 transcatheter 阀门的识别联系了复杂并发症。CT angiography 关于大动脉的体环直径和环绕的区域的全部的定义是更精确的。二维(2D ) echocardiography,与 3D 成像技术(MSCT, MRI 和 3D 脚趾) 相比低估大动脉的阀门体环直径。三维的脚趾成像提供类似于 MSCT 交付的那些的大动脉的阀门体环的大小。pre 程序的 MSCT 组成最小化 paravalvular 的存在的标准答案形式大动脉的流回,最经常的复杂并发症之一。TOE/TTE 和 MSCT 性能能预言心律调整器培植 procedural 以后的可能性。一位新短暂或坚持的先生的存在能被脚趾估计很好。TTE 和脚趾,开始在于为柱子 TAVI 评估的基本考试。在 transcatheter 心阀门失败的情况下, MSCT 能被用作另外的成像技术。 | Emmanouil Chourdakis Ioanna Koniari Nicholas G Kourlis Dimitrios Velissaris Nikolaos Koutsogiannis Grigorios Tsigkas Karl Eugen Hauptmann Bruno Sontag George Hahalis | 2018 | Journal of Geriatric Cardiology2018，15，1： | 4 |
| 4 | Transcatheter versus surgical aortic valve replacement in severe, symptomatic aortic stenosis显示文摘大动脉的狭窄(作为) 是瓣膜的心疾病在的最普通的类型老。外科的大动脉的阀门代替(SAVR ) 是为对待的标准实践严重、作为征兆,却最近新治疗选择出现了。Transcatheter 大动脉的阀门代替(TAVR ) 现在是在在高外科的风险的病人的一种确定的治疗选择。在这评论,我们集中于最近的开发并且以功效和安全在特定的人口比较二个治疗方法(例如在有优先的胸的外科的历史的病人,采用的麻醉打字,存取使用的地点或为永久踱步需要) 。comorbidities (肺的高血压,动脉的高血压和肥胖悖论) 的影响,在象应得进一步的调查的问题一样的 transcatheter 阀门技术的 TAVR 对 SAVR 和进展的划算进一步被讨论。而且,在不同风险范畴(极其高、高、中间、低的风险) 的病人的 TAVR 的结果和复杂并发症被分析。我们强烈相信在下列年期间, TAVR 可以在病人的一个更宽广的组作为选择的治疗演变与与中间、高风险的特征作为并且在那些以外征兆。 | Tsigkas Grigorios Despotopoulos Stefanos Makris Athanasios Koniari Ioanna Armylagos Stylianos Davlouros Periklis Hahalis George | 2018 | Journal of Geriatric Cardiology2018，15，1： | 2 |
| 5 | Emergence, development, and future of cardio-oncology in China: cardiohypersensitivity, cardiotoxicity and the Kounis syndrome显示文摘To the Editor:Cancer and cardiovascular disease constitute the two major causes of death worldwide. Whereas the incidence of cancer increases among adults up to 74 years of age, above this age the cardiovascular disease surpasses cancer as the primary cause of mortality.[1] Currently, chemotherapy, radiation therapy, and surgery are the main modalities for the treatment of cancer. However, chemotherapy can induce cardiovascular worsening, manifesting as acute and chronic symptomatology. Therefore, the verv interesting report published in Chinese Medical Journal[2] concerning a 60-year-old male patient suffering from coronary artery disease and squamous cell carcinoma of the left lung who developed an ST segment elevation myocardial infarction following treatment with afatinib (tyrosine kinase inhibitor) and gemcitabine (antimetabolite pyrimidine antagonist) and cisplatin (platinum based DNA replication inhibitor) and the subsequent discussion raise several important considerations on cardiac toxicity, cardiac hypersensitivity and the Kounis-hypersensitivity acute coronary syndrome. | Nicholas G. Kounis Ioanna Koniari Panagiotis Plotas George D. Soufras Grigorios Tsigkas Periklis Davlouros George Hahalis | 2019 | Chinese Medical Journal2019，，6： | 2 |
| 6 | Kounis syndrome caused by double allergens: the more allergens present, the easier, the quicker, and the more severe the anaphylaxis显示文摘To the Editor:In the very interesting report published in the Chinese Medical Journal,[1] a 42-year-old Chinese male patient who had not any previous history of cardiovascular disease,but only bee stings without any sequelae,was stung again while was cycling outdoors. | Nicholas G.Kounis Ioanna Koniari Panagiotis Plotas George D.Soufras Grigorios Tsigkas Periklis Davlouros George Hahalis | 2020 | Chinese Medical Journal2020，，15： | 2 |
| 7 | Acute Myocardial Infarction Induced by Anaphylaxis in China: The Kounis Syndrome显示文摘 | Nicholas G Kounis Ioanna Koniari Emmanouil Chourdakis George D Soufras Grigorios Tsigkas Periklis Davlouros George Hahalis | 2018 | Chinese Medical Journal2018，，19： | 2 |
| 8 | Cardiac mortality in {beta}-thalassemia major: resting but not dobutamine stress echocardi- ography predicts mortality among initially cardiac disease-flee patients in a prospective 12-year study 显示文摘 | Hahalis G Kourakli A Gerasimidou I | 2009 | Eur J Heart Fail2009，11，12： | 1 |
| 9 | Heart failure in - thalassemia syndromes : A decade of progress 显示文摘 | Hahalis G Alexopoulos D Kremastinos DT | 2005 | American J Med2005，118，： | 1 |
| 10 | The heart seems to be the primary site and the target of anaphylaxis resulting in the development of Kounis syndrome显示文摘 | Kounis NG Davlouros P Hahalis G | 2012 | Intern Emerg Med2012，7，2： | 1 |
| 11 | Coronary stents,hypersensitivity reactions,and the Kounis syndrome显示文摘 | Kounis NG Hahalis G Theoharides TC | 2007 | J Interv Cardiol2007，20，5： | 1 |
| 12 | Anaphylactic Shock: Kounis HypCT-sensitivity-Associated syndrome seems to be the primary cause显示文摘 | Kounis NG Soufras GD Hahalis G | 2013 | N AmJ Med Sci2013，5，11： | 1 |
| 13 | Mesalamine hypersensitivity and Kounis syndrome in a pediatric ulcerative colitis patient显示文摘5-aminosalicylic acid (mesalamine) rarely induces hyper-sensitivity reactions. If chest pain associated with atypical electrocardiographic changes are seen during its adminis-tration, one should always bear in mind typeⅠvariant of Kounis syndrome. This variant includes patients, of any age, with normal coronary arteries, without predisposing factors for coronary artery disease, in whom the acute release of inflammatory mediators from mast cells can induce either sudden coronary artery narrowing, without increase of cardiac enzymes and troponins, or coronary artery spasm that progresses to acute myocardial infarction, with elevated cardiac enzymes and troponins. | Geoge N Kounis Sophia A Kouni George Hahalis Nicholas G Kounis | 2008 | World Journal of Gastroenterology2008，14，46： | 1 |
| 14 | Prasugrel Overcomes High On-Clopidogrel Platelet Reactivity Post-Stenting More Effectively Than High-Dose (150-mg) Clopidogrel显示文摘 | Dimitrios Alexopoulos Gerasimos Dimitropoulos Periklis Davlouros Ioanna Xanthopoulou George Kassimis Eleana F. Stavrou George Hahalis Aglaia Athanassiadou | 2011 | JACC: Cardiovascular Interventions2011，，： | 1 |
| 15 | Are bioabsorbable and biodegradable polymer scaffolds still safe or Kounis syndrome is still watching for?显示文摘 | Kounis NG Soufras GD Tsigkas G Hahalis G | 2014 | Chinese Medical Journal2014，，23： | 1 |
| 16 | The heart seems to be the primary site and the target of anaphylaxis resulting in the development of Kounis syndrome显示文摘 | KounisNG Davlouros P Hahalis G | 2012 | Intern Emerg Med2012，7，52： | 1 |
| 17 | Stent restenosis, pathophysiology and treatment options: a 2010 update 显示文摘 | Tsigkas GG Karantalis V Hahalis G | 2011 | Hel- lenicI Cardiol2011，52，2： | 1 |
| 18 | Revascularization strategies for stable multivessel and unprotected left main coronary artery disease: from BARI to SYNTAX 显示文摘 | Hahalis G Dangas G Davlouros P | 2011 | IntJ Cardiol2011，153，2： | 1 |
| 19 | Incidence, pathophysiology, predictive factors and prognostic implications of new onset atrial fibrillation following transcatheter aortic valve implantation显示文摘 | Ioanna Konlari Grigorios Tsigkas Nikolaos Kounisx Dimitrios Velissaris Emmanouil Chourdakis Periklis Davlouros George Hahalis | 2018 | Journal of Geriatric Cardiology2018，15，1： | 1 |
| 20 | Stent restenosis,pathophysiology and treatment options:a 2010 update显示文摘 | Tsigkas GG Karantalis V Hahalis G | | 0，，： | 1 |
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