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322篇 您的检索式:作者名="Hall L T"
    题名 作者 年代 出处 被引量
1全球药物滥用的疾病负担:来自2010年全球疾病负担研究显示文摘背景:直到目前还没有研究者系统地估计过全球及区域性的苯丙胺类、大麻、可卡因和阿片类药物依赖的患病率及其造成的疾病负担。我们旨在用伤残损失寿命年(YLDs)、过早死亡损失寿命年(YLLs)和伤残调整寿命年(DALYs)来估计药物依赖的患病率和其造成的疾病负担。方法:采用贝叶斯Meta回归的方法(Dis Mod-MR)对药物依赖的流行病学研究及2010年全球疾病、伤害及危险因素负担研究(GBD 2010)进行了系统综述,估计人群水平的药物依赖患病率。GBD 2010通过代表性社区调查和基于互联网的调查计算出新的失能权重。我们把估计的药物依赖患病率和新的失能权重结合起来估算药物依赖导致的YLDs、YLLs、DALYs和其作为相关疾病危险因素时导致的YLDs、YLLs和DALYs。结果:2010年,药物依赖直接造成了2千万的DALYs(95%UI(不确定区间)1.3-2.54千万),占全球全因DALYs的0.8%(0.6%-1.0%)。世界范围内,相比于其他药物,越来越多的人依赖于阿片类和苯丙胺类药物。阿片类药物依赖直接造成的疾病负担最大(DALYs为920万,95%UI为710-1140万)。在某些地区,药物依赖导致的DALYs所占比例比其他地区高出20倍,收入越高的国家药物依赖造成的负担所占比例也越高。注射吸毒所致HIV感染造成210万的DALYs(95%UI 110-360万),所致HCV感染导致50.2万的DALYs(95%UI 28.6-89.1万)。苯丙胺类药物依赖所致自杀造成85.4万的DALYs(95%UI 29.1-179.1万),阿片类药物依赖所致自杀造成67.1万的DALYs(95%UI 32.9-173.0万),可卡因依赖所致自杀造成32.4万的DALYs(95%UI 10.9-68.2万)。药物依赖导致的疾病负担最高的国家(>650 DALYs/10万人)包括美国,英国,俄罗斯和澳大利亚。结论:药物滥用是造成全球疾病负担的一个重要因素。为减少人群水平的疾病负担,我们需采取有效的措施(比如给予阿片类药物依赖者替代治疗及针具交换等)降低阿片类药物依赖和注射吸毒导致的疾病负担。王同瑜 Degenhardt L Whiteford HA Ferrari AJ Baxter AJ Charlson FJ Hall WD Freedman G Burstein R Johns Engell RE Flaxman A Murray CJ Vos T 2015中国药物依赖性杂志2015,24,6:3
2Fingerprints of globalwarming on wild animals and plants显示文摘ROOTT L PRICE J T’HALL K R 2003Nats2003,421,:1
3Fingerprints of global warming on wild animals and plants显示文摘Root T L Price J T Hall R K 2003Nature2003,421,:1
4Gianturco-Rosch expandable Z-stents in the treatment of superior vena cava syndrome显示文摘ROSCH J UCHIDA B T HALL L D 1992Cardiovasc Intervent Radiol1992,15,5:1
5Pharmacokinetics of ceffiofur sodium and ceftiofur crystalline free acid in neonatal foals 显示文摘Hall T L L A Tell 2011Journal of Veterinary Pharmacology and Therapeutics2011,34,4:1
6Sequence and spacing of TATA box elements are critical for accurate initiation from the β-phaseolin promoter显示文摘GRACE M L CHANDRASEKHARAN M B HALL T C CROWE A J 2004Biological Chemistry2004,279,:1
7Secondary prevention of coronary artery disease显示文摘Halls L Lorenc T 2010Am Fam Physician2010,81,3:1
8pH dependence and com- petitive product inhibition of the carboxypeptidase A catalyzed hydrolysis of O-(trans-cinnamoyl)-L-beta-phenyllactate 显示文摘Hall P L Kaiser B L Kaiser E T 1969Journal of the American Chemical Society1969,91,2:1
9Effect of adverse weather conditions on speed- flow- occupancy relationships显示文摘IBRAHIM A T HALL F L 1994Transportation Research Record1994,,1457:1
10The influence of crown rust on tiller production and survival of peren- nial ryegrass (Lolium perenne ) plants in simulated swards显示文摘Plummer R M Hall R L Watt T A 1990Grass and Forge Science1990,45,:1
11Nimbus-7 SMMR Derived Global Snow Cover Parameters 显示文摘CHANG A T C FOSTER J L HALL D K 1987Annals of Glaciology1987,9,:1
12Intratumoral lymphatics and lymph node metastases in papillary thyroid carcinoma显示文摘HALL F T FREEMAN J L ASA S L 0,,07:1
13Denitrification in the water column of the central Baltic Sea显示文摘Dalsgaard T De Brabandere L Hall P O J 2013Geochimica et Cosmochimica Acta2013,106,:1
14Three-dimensional millimeter-wave imaging for concealed weapon detection显示文摘Sheen D M McMakin D L Hall T E 0,,09:1
15Spatial patterns in wet and dry deposition of atmospheric mercury and trace elements in central Illinois, USA 显示文摘Lynam M M Dvonch J T Hall N L 2014Environmental Science and Pollution Research2014,21,6:1
16Fast Fuzzy Clustering 显示文摘Cheng T W Goldgof D B Hall L O 1998Fuzzy Sets and Systems1998,93,1:1
17Stages of embryonic development in the Atlantic Cod Gadus morhua 显示文摘Hall T E Smith P Johnston L A 2004J Morphol2004,259,3:1
18Some high pressure studies on ytterbium显示文摘Hall H T Merrill L 1963The Inorganic Chemistry1963,2,3:1
19Ceric ammonium nitriate oxidation of polynuclear aromatic hydrocarbons to quinone显示文摘Ho T L Hall T W Wong C M 1973Synthesis1973,4,:1
20Protean and Boundaryless Careers: An Empirical Ex- ploration 显示文摘BRISCOE J P HALL D T FRAUTSCHY D R L 2006Journal of Vocational Behavior2006,69,1:1
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