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| 1 | Pretreated quercetin protects gerbil hippocampal CA1 pyramidal neurons from transient cerebral ischemic injury by increasing the expression of antioxidant enzymes显示文摘Quercetin(QE; 3,5,7,3′,4′-pentahydroxyflavone), a well-known flavonoid, has been shown to prevent against neurodegenerative disorders and ischemic insults. However, few studies are reported regarding the neuroprotective mechanisms of QE after ischemic insults. Therefore, in this study, we investigated the effects of QE on ischemic injury and the expression of antioxidant enzymes in the hippocampal CA1 region of gerbils subjected to 5 minutes of transient cerebral ischemia. QE was pre-treated once daily for 15 days before ischemia. Pretreatment with QE protected hippocampal CA1 pyramidal neurons from ischemic injury, which was confirmed by neuronal nuclear antigen immunohistochemistry and Fluoro-Jade B histofluorescence staining. In addition, pretreatment with QE significantly increased the expression levels of endogenous antioxidant enzymes Cu/Zn superoxide dismutase, Mn superoxide dismutase, catalase and glutathione peroxidase in the hippocampal CA1 pyramidal neurons of animals with ischemic injury. These findings demonstrate that pretreated QE displayed strong neuroprotective effects against transient cerebral ischemia by increasing the expression of antioxidant enzymes. | Bai Hui Chen Joon Ha Park Ji Hyeon Ahn Jeong Hwi Cho In Hye Kim Jae Chul Lee Moo-Ho Won Choong-Hyun Lee In Koo Hwang Jong-Dai Kim Il Jun Kang Jun Hwi Cho Bich Na Shin Yang Hee Kim Yun Lyul Lee Seung Min Park | 2017 | Neural Regeneration Research2017，12，2： | 9 |
| 2 | Glehnia fittoralis Extract Promotes Neurogenesis in the Hippocampal Dentate Gyrus of the Adult Mouse through Increasing Expressions of Brain-Derived Neurotrophic Factor and Tropomyosin-Related Kinase B显示文摘 | Joon Ha Park Bich Na Shin Ji Hyeon Ahn Jeong Hwi Cho Tae-Kyeong Lee Jae-Chul Lee Yong Hwan Jeon II Jun Kang Ki-Yeon Yoo In Koo Hwang Choong Hyun Lee Yoo Hun Noh Sung-Su Kim Moo-Ho Won Jong Dai Kim | 2018 | Chinese Medical Journal2018，，6： | 6 |
| 3 | Frequency of CYP2C9 alleles in Koreans and their affects on Iosartan pharmacokinetics显示文摘 | Jung-woo BAE Chang-ik CHOI Mi-jeong KIM Da-hee OH Seul-ki KEUM Jung-in PARK Bolhyo KIM Hye-kyoung BANG Sung-gon OH Byung-sung KANG Hye-in LEE Yundeong LEE Hyun-joo PARK Hae-deun KIM Ji-hey HA Hee jung SHIN Young-hoon KIM Han-sung NA Myeon-woo CHUNG Soon-young HAN Seung-hee KIM Choon-gon JANG Seok-yong LEE | 2011 | Acta Pharmacologica Sinica2011，32，10： | 4 |
| 4 | High-performance colorful semitransparent perovskite solar cells with phase-compensated microcavities显示文摘 | Kyu-Tae Lee Ji-Yun Jang Na Young Ha Soonil Lee Hui Joon Park | 2018 | Nano Research2018，11，5： | 3 |
| 5 | Patient preferences for stroke outcomes显示文摘 | Solomon NA Glick HA Russo CJ | 1994 | Stroke1994，25，9： | 1 |
| 6 | Mortality, morbidity and complicati显示文摘 | Doll HA B/ack NA McPherson K | 1992 | J Urol1992，147，6： | 1 |
| 7 | Tissue engineered regeneration of completely transected spinal cord using human mesenchymal stem cells显示文摘 | Kkot Nim Kang Da Yeon Kim So Mi Yoon Ju Young Lee Bit Na Lee Jin Seon Kwon Hyo Won Seo Il Woo Lee Ha Cheol Shin Young Man Kim Hyun Soo Kim Jae Ho Kim Byoung Hyun Min Hai Bang Lee Moon Suk Kim | 2012 | Biomaterials2012，，19： | 1 |
| 8 | A comparative dosime- tric study of adjuvant 3D conformal radiotherapy for operable stomach cancer versus AP-PA conventional radiotherapy in NCI- Cairo显示文摘 | E1-Hossiny HA Diab NA E1-Taher MM | 2009 | J Egypt Natl Canc Inst2009，21，3： | 1 |
| 9 | Risk of arterial thrombotic events in inflammatory bowel disease显示文摘 | Ha C Magowan S Accortt NA | | 0，，06： | 1 |
| 10 | Breast cancer risk in young women and history of selected medical conditions显示文摘 | Weiss HA Brinton LA Potischman NA | 1999 | Int J Epidemiol1999，28，5： | 1 |
| 11 | Modulatory effects of curcumin,silybin-phytosome and alpha-R-lipoic and against thioacetamide induced liver cirrhosis in rats显示文摘 | ALI SO DARWISH HA ISMAIL NA | 2014 | Chem Biol Interact2014，216，： | 1 |
| 12 | Microbubbles as a vehicle for gene and drug delivery: current clinical implications and future perspectives显示文摘 | Geis NA Katus HA Bekeredjian R | 2012 | Curr Pharm Des2012，18，15： | 1 |
| 13 | The protection role of heat shock protein 70 (HSP-70) in the testes of cadmium-exposed rats显示文摘 | Selim ME Rashedel HA Aleisa NA | 2012 | Bioinformation2012，8，1： | 1 |
| 14 | Microglia activation by SIV-infected macrophages: alterations in morphology and cytokinesecretion显示文摘 | Renner NA Sansing HA Morici LA | 2012 | J Neurovirol2012，18，3： | 1 |
| 15 | Multi-decadal changes in fish communi- ties Jeju Island in relation to climate change显示文摘 | Jung S Ha S Na H | 2013 | Kor J Fish Aqnat Sci2013，46，2： | 1 |
| 16 | Endosonographic features of esophageal granular cell tumors using a high-frequency catheter probe显示文摘 | Dong Uk Kim Gwang Ha Kim Dong Yup Ryu Dong Gun Lee Jae Hoon Cheong Bong Eun Lee Geun Am Song Do Youn Park Na Ri Shin Hoseok I Mitsuhiro Kida | 2011 | Scandinavian Journal of Gastroenterology2011，，2： | 1 |
| 17 | Pyrolysis kinetics of coking coal mixed with biomass under non-isothermal and isothermal conditions显示文摘 | Ha Myung Jeong Myung Won Seo Sang Mun Jeong Byung Ki Na Sang Jun Yoon Jae Goo Lee Woon Jae Lee | 2014 | Bioresource Technology2014，，： | 1 |
| 18 | Microbubbles as a vehicle forgene and drug delivery current clinical implications and futureperspectives 显示文摘 | Geis NA Katus HA Bekeredjian R | 2012 | Curr Pharm Des2012，18，15： | 1 |
| 19 | Mortality,morbidity and complications following tran surethral resection of the pros 2t ate for benign prostatic hypertrophy显示文摘 | Doll HA Bl ack NA McPher son K | 1992 | J Urol1992，147，15： | 1 |
| 20 | In vitro and In vivo antimicrobial activity of propolis on the microbiota from gastrointestinal tract of chickens显示文摘 | Miroslava Ka?ániová Katarína Rovná Henrieta Arpá?ová Juraj ?uboň Luká? Hleba Jaroslav Pochop Simona Kunová Peter Ha??ík | 2012 | Journal of Environmental Science and Health Part A2012，，11： | 1 |
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