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| 1 | Dynamics of oil price, precious metal prices, and exchange rate显示文摘 | Ramazan Sari Shawkat Hammoudeh Ugur Soytas | 2009 | Energy Economics2009，，2： | 2 |
| 2 | Insight into molecular mechanisms underlying hepatic dysfunction in severe COVID-19 patients using systems biology显示文摘BACKGROUND The coronavirus disease 2019(COVID-19),a pandemic contributing to more than 105 million cases and more than 2.3 million deaths worldwide,was described to be frequently accompanied by extrapulmonary manifestations,including liver dysfunction.Liver dysfunction and elevated liver enzymes were observed in about 53%of COVID-19 patients.AIM To gain insight into transcriptional abnormalities in liver tissue of severe COVID-19 patients that may result in liver dysfunction.METHODS The transcriptome of liver autopsy samples from severe COVID-19 patients against those of non-COVID donors was analyzed.Differentially expressed genes were identified from normalized RNA-seq data and analyzed for the enrichment of functional clusters and pathways.The differentially expressed genes were then compared against the genetic signatures of liver diseases including cirrhosis,fibrosis,non-alcoholic fatty liver disease(NAFLD),and hepatitis A/B/C.Gene expression of some differentially expressed genes was assessed in the blood samples of severe COVID-19 patients with liver dysfunction using qRT-PCR.RESULTS Analysis of the differential transcriptome of the liver tissue of severe COVID-19 patients revealed a significant upregulation of transcripts implicated in tissue remodeling including G-coupled protein receptors family genes,DNAJB1,IGF2,EGFR,and HDGF.Concordantly,the differential transcriptome of severe COVID-19 liver tissues substantially overlapped with the disease signature of liver diseases characterized with pathological tissue remodeling(liver cirrhosis,Fibrosis,NAFLD,and hepatitis A/B/C).Moreover,we observed a significant suppression of transcripts implicated in metabolic pathways as well as mitochondrial function,including cytochrome P450 family members,ACAD11,CIDEB,GNMT,and GPAM.Consequently,drug and xenobiotics metabolism pathways are significantly suppressed suggesting a decrease in liver detoxification capacity.In correspondence with the RNA-seq data analysis,we observed a significant upregulation of DNAJB1 and HSP90AB1 as well as significant downregulation of CYP39A1 in the blood plasma of severe COVID-19 patients with liver dysfunction.CONCLUSION Severe COVID-19 patients appear to experience significant transcriptional shift that may ensue tissue remodeling,mitochondrial dysfunction and lower hepatic detoxification resulting in the clinically observed liver dysfunction. | Sarah Musa Hammoudeh Arabella Musa Hammoudeh Poorna Manasa Bhamidimarri Bassam Mahboub Rabih Halwani Qutayba Hamid Mohamed Rahmani Rifat Hamoudi | 2021 | World Journal of Gastroenterology2021，27，21： | 2 |
| 3 | Return and Volatility Connectedness between Stock Markets and Macroeconomic Factors in the G-7 Countries显示文摘We examine the relationship between return and volatility of the stock markets and macroeconomic fundamentals for the G-7 countries by using monthly data ranging from July 1985 to June 2015. To meet this end, we apply the spillover index approach based on the generalized VAR framework developed by Diebold and Yilmaz (2012, 2014). The empirical analysis shows strong interactions between the returns and volatilities of the G-7 stock markets and the considered set of corresponding macroeconomic factors including industrial production, money supply, interest rates, inflation, oil prices and exchange rates. The return and volatility spillover transmission/reception dynamics of the relationships between these stock markets and the macroeconomic fundamentals have changed after the global financial crisis of 2008. Our findings provide useful insights for investors and policy makers concerned with the unprecedented swings in the stock markets of G-7 countries. | Ghulam Abbas Shawkat Hammoudeh Syed Jawad Hussain Shahzad Shouyang Wang Yunjie Wei | 2019 | Journal of Systems Science and Systems Engineering2019，28，1： | 2 |
| 4 | Oil Sensitivity and Systematic Risk in Oil-sensitive Stock Indices 显示文摘 | Shaw Kat Hammoudeh and Li Huimin 2005 | 2005 | Journal of Economics and Business2005，，57： | 1 |
| 5 | The impact of the Asian crisis on the behavior of US and international petroleum prices显示文摘 | Hammoudeh S Huimin L | | 0，，： | 1 |
| 6 | Millimetric wavelengths radiowave propagation for line of sight indoor mieroeellular mobile eommunieations显示文摘 | Hammoudeh A K | 1995 | IEEE Transaetions on Antennas and Propogation1995，44，3： | 1 |
| 7 | Metal volatility in presence of oil and interest rate shocks 显示文摘 | Shawkat Hammoudeh Yuan Yuan | 2008 | Energy Economics2008，，30： | 1 |
| 8 | Causality and volatility spillo- vers among petroleum prices of WTI, gasoline and heating oil in different locations locations 显示文摘 | Hammoudeh S Huimin L jeon B | 2003 | North American Journal of Eco- momics and Finance2003，，14： | 1 |
| 9 | Volatility behavior of oil, industrial commodity and stock markets in a regime-switching environment 显示文摘 | Choi K Hammoudeh S | 2010 | Energy Policy2010，，38： | 1 |
| 10 | Sustained remission with etanercept tapering in early rheumatoid arthritis显示文摘 | Emery P Hammoudeh M Fitzgerald 0 | 2014 | N EnglJ Med2014，371，19： | 1 |
| 11 | Small-molecule perturbation of competing interactions between e-Myc and Max显示文摘 | Follis AV Hammoudeh DI Daab AT | 2009 | Bioorg Med Chem Lett2009，19，3： | 1 |
| 12 | Selective hydrogenation of cinnamaldehyde over Pd/SiO 2 catalysts: selectivity promotion by alloyed Sn显示文摘 | A Hammoudeh S Mahmoud | 2003 | Journal of Molecular Catalysis A Chemical2003，，1： | 1 |
| 13 | A time-va- rying Copula approach to oil and stock market dependence: the case of transition economies 显示文摘 | Aloui R Hammoudeh S Nguyen D K | 2013 | Energy Economics2013，，39： | 1 |
| 14 | Discovery of novel Myc-Max heterodimer disruptors with a three-dimen- sional pharmacophore model 显示文摘 | Mustata G Follis AV Hammoudeh DI | 2009 | J Med Chem2009，52，5： | 1 |
| 15 | Asymmetric adjustments in oil and metals markets 显示文摘 | Hammoudeh S Chen L Fattouh B | 2010 | Energy Journal2010，4，： | 1 |
| 16 | Hydrogenation of cinnamaldehyde over sol-gel Pd/SiO2 catalysts:kinetic aspects and modification of catalytic properties by Sn,Ir and Cu additives显示文摘 | Mahmoud S Hammoudeh A Gharaibeh S | 2002 | Journal of Molecular Catalysis A:Chemical2002，178，12： | 1 |
| 17 | Oil sensitivity and systematic risk in oil-sensitive stock indices显示文摘 | Hammoudeh S Li Huimin | 2005 | Journal of Economics and Business2005，57，1： | 1 |
| 18 | Measurements and Predictions of Attenuation and Scatter of Microwave Signals by Trees 显示文摘 | ALNUAIMI M O HAMMOUDEH A M | 1994 | IEEE Prnc- Microw Antennas Propag1994，141，2： | 1 |
| 19 | Inappropriateuse of intravenous PPI for stress ulcer prophylaxis in an inner city community hospital显示文摘 | Perwaiz MK Posner G Hammoudeh F | 2010 | J Clin Med Res2010，2，5： | 1 |
| 20 | Inappropriate Use of Intravenous PPI for Stress Ulcer Prophylaxis in an Inner City Community Hospital显示文摘 | Perwaiz MK Posner G Hammoudeh F | 2010 | J Clin Med Res2010，2，5： | 1 |
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