|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | PredSL: A Tool for the N-terminal Sequence-based Prediction of Protein Subcellular Localization显示文摘The ability to predict the subcellular localization of a protein from its sequence is of great importance, as it provides information about the protein’s function. We present a computational tool, PredSL, which utilizes neural networks, Markov chains, profile hidden Markov models, and scoring matrices for the prediction of the subcellular localization of proteins in eukaryotic cells from the N-terminal amino acid sequence. It aims to classify proteins into five groups: chloroplast, thylakoid, mitochondrion, secretory pathway, and “other”. When tested in a five- fold cross-validation procedure, PredSL demonstrates 86.7% and 87.1% overall accuracy for the plant and non-plant datasets, respectively. Compared with Tar- getP, which is the most widely used method to date, and LumenP, the results of PredSL are comparable in most cases. When tested on the experimentally verified proteins of the Saccharomyces cerevisiae genome, PredSL performs com- parably if not better than any available algorithm for the same task. Further- more, PredSL is the only method capable for the prediction of these subcellu- lar localizations that is available as a stand-alone application through the URL: http://bioinformatics.biol.uoa.gr/PredSL/. | Evangelia I. Petsalaki Pantelis G. Bagos Zoi I. Litou Stavros J. Hamodrakas | 2006 | Genomics, Proteomics & Bioinformatics2006，4，1： | 5 |
| 2 | Secondary Structure of Chorion Proteins of the Teleostean Fish Dentex dentex by ATR FT-IR and FT-Raman Spectroscopy显示文摘 | V.A. Iconomidou D.G. Chryssikos V. Gionis M.A. Pavlidis A. Paipetis S.J. Hamodrakas | 2000 | Journal of Structural Biology2000，，2： | 1 |
| 3 | Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls显示文摘 | Nikolopoulos GK Dimou NL Hamodrakas SI | 2008 | J Clin Periodontol2008，35，9： | 1 |
| 4 | Analysis of molecular recognition features (MoRFs) in membrane proteins 显示文摘 | Kotta-Loizou I Tsaousis G N Hamodrakas S J | 2013 | Bioehim Biophys Acta2013，1834，4： | 1 |
| 5 | Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls显示文摘 | Nikolopoulos GK Dimou NL Hamodrakas S J | 2008 | J Clin Periodontol2008，35，9： | 1 |
| 6 | Unique features of the structural model of hard'cuticle proteins: implications for chitin protein interactious and cross-linking in cuticle 显示文摘 | Iconomidou V A Willis J H Hamodrakas S J | 2005 | Insect Binchem Mol Biol2005，35，： | 1 |
| 7 | A structural model of the chitin-binding domain of cuticle proteins 显示文摘 | Hamodrakas S J Willis J H Iconomidou V A | 2002 | Insect Biochem Mol Biol2002，32，： | 1 |
| 8 | Predictive value of B- type natriuretic peptides in detecting latent left ventricular diastolic dysfunction in beta-thalassemia major显示文摘 | Kremastinos D T Hamodraka E Parissis J | 2010 | Am Heart J2010，159，1： | 1 |
| 9 | Is 13-pleated sheet the molecular conformation which dictates formation of heli- coidal cuticle?显示文摘 | Iconomidou VA Judith HW Hamodrakas SJ | 1999 | Insect Biochem Mol Biol1999，29，3： | 1 |
| 10 | An amy- loidogenic determinant in N-terminal pro-brain natriuretic peptide (NT-proBNP):implications for cardiac amyloid- oses显示文摘 | Iconomidou VA Pheida D Hamodraka ES | 2012 | Biopolymers2012，98，1： | 1 |
| 11 | A hierarchical artificial neural network system for the classification of transmembrane proteins显示文摘 | PASQUIE-R C HAMODRAKAS S J | 1999 | Protein Engineering1999，12，8： | 1 |
| 12 | The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14 094 cases and 17 760 controls显示文摘 | Pantelis G Bagos Antigoni L Elefsinioti Georgios K Nikolopoulos Stavros J Hamodrakas | 2007 | Journal of Hypertension2007，，3： | 1 |
| 13 | Evaluation of methods for predicting the topology of beta-barrel outer membrane proteins and a consensus prediction method 显示文摘 | Bagos P G Liakopoulos T D Hamodrakas S J | 2005 | BMC Bioinformatics2005，6，： | 1 |
| 14 | OMPdb : a database of 13- barrel outer membrane proteins from Gram-negative bacteria显示文摘 | Tsirigos K D Bagos P G Hamodrakas S J | 2011 | Nu- cleic Acids Res2011，39，： | 1 |
| 15 | Cytokine gene polymorphisms in periodontal disease:a meta-analysis of 53 studies including 4178 cases and 4590 controls显示文摘 | Nikolopoulos GK Dimou NL Hamodrakas SJ | 2008 | J Clin Periodontol2008，35，9： | 1 |
| 16 | Haloadaptation: Insights from comparative modeling studies of halophilic archaeal DHFRs显示文摘 | KASTRITIS P L PAPANDREOU N C HAMODRAKAS S J | 2007 | Int J Biol Macromol2007，41，4： | 1 |
| 17 | Unique features of the structural model of hard cuticle proteins : implications for chitin protein interactions and cross-linking in cuticle显示文摘 | Ieonomidou V A Willis J H Hamodrakas S J | 2005 | Insect Biochem Mol Biol2005，35，： | 1 |
| 18 | Cytokine gene polymorphisms in periodontal disease: A meta-analysis of 53 stu- dies including 4178 cases and 4590 controls显示文摘 | Nikolopoulos GK Dimou NL Hamodrakas SJ | 2008 | J Clin Periodontol2008，35，9： | 1 |
| 19 | Apolipoprotein E polymorphisms and type 2 diabetes:a meta- analysis of 30 studies including 5 423 cases and 8 197 con- trols显示文摘 | ANTHOPOULOS P G HAMODRAKAS S J BAGOS P G | 2010 | Mol Genet Metab2010，100，3： | 1 |
| 20 | Cytokine gene polymorphisms in periodontal disease:a meta-analysis of 53 studies including 4178 cases and 4590 controls 显示文摘 | Nikolopoulous GK Dimou NL Hamodrakas SJ | 2008 | J Clin Periodontol2008，35，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员