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| 1 | 颅内动脉瘤显微外科手术163例分析显示文摘目的 总结颅内动脉瘤显微外科手术的治疗经验。方法 统计近年 2年来显微外科手术夹闭的 16 3例颅内动脉瘤患者的临床资料、手术方式及术后转归。结果 成功夹闭 16 2例 ,5例为栓塞失败后改为手术夹闭。术中过早破裂 31例 ,其中 1例在切开脑膜前破裂 ,未予夹闭。 112例恢复正常工作 (6 9 6 % ) ,轻残 19例 ,重度残废 2 1例 ,死亡 8例 (4 9% ) ,术后脑积水 32例。结论 颅内动脉瘤一旦诊断明确 ,即应积极处理 ,Hunt和Hess 4~ 5级者入院后延迟手术可能减少手术死亡率 ,但在等待期间可能增加再破裂出血的危险 ,因而总死亡率不减少。颅底外科入路及精细的显微操作可减少术中过早破裂。前循环和后循环动脉瘤的术中处理有不同 ,脑积水为最常见的远期并发症 。 | 陈建良 吴耀晨 陈锦伦 陈旭东 赵永阳 陈洪 Je Hyuk Lee Soo Han Kim | 2000 | 中华神经外科杂志2000，16，4： | 24 |
| 2 | A sulfur self-doped multifunctional biochar catalyst for overall water splitting and a supercapacitor from Camellia japonica flowers显示文摘A versatile use of a sulfur self-doped biochar derived from Camellia japonica(camellia)flowers is demonstrated as a multifunctional catalyst for overall water splitting and a supercapacitor.The native sulfur content in the camellia flower facilitates in situ self-doping of sulfur,which highly activates the camellia-driven biochar(SA-Came)as a multifunctional catalyst with the enhanced electron-transfer ability and long-term durability.For water splitting,an SA-Came-based electrode is highly stable and shows reaction activities in both hydrogen and oxygen evolution reactions,with overpotentials of 154 and 362 mV at 10 mA cm^(−2),respectively.For supercapacitors,SA-Came achieves a specific capacitance of 125.42 F g^(−1)at 2 A g^(−1)and high cyclic stability in a three-electrode system in a 1 M KOH electrolyte.It demonstrated a high energy density of 34.54 Wh kg^(−1)at a power density of 1600 W kg^(−1)as a symmetric hybrid supercapacitor device with a wide working potential range of 0-1.6 V. | Chengkai Xia Subramani Surendran Seulgi Ji Dohun Kim Yujin Chae Jaekyum Kim Minyeong Je Mi-Kyung Han Woo-Seok Choe Chang Hyuck Choi Heechae Choi Jung Kyu Kim Uk Sim | 2022 | Carbon Energy2022，4，4： | 3 |
| 3 | Sequential disruption of ALV host receptor genes reveals no sharing of receptors between ALV subgroups A, B, and J显示文摘Background: Previously, we showed that targeted disruption of viral receptor genes in avian leukosis virus(ALV)subgroups using clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9))-based genome editing confers resistance to ALV subgroups B and J. Here, we used the same strategy to target the receptor expressed by ALV subgroup A(TVA) and generate chicken cells resistant to infection by this virus.Results: CRISPR/Cas9-based disruption of exon 2 within the tva gene of DF-1 fibroblasts conferred resistance to infection by ALV subgroup A regardless of whether frameshift mutations were introduced during editing. Conversely,overexpression of the wild-type TVA receptor(wtTVA) by tva-modified DF-1 clones restored susceptibility to ALV subgroup A. The results confirm that exon 2, which contains the low-density lipoprotein receptor class A domain of TVA, is critical for virus entry. Furthermore, we sequentially modified DF-1 cells by editing the tva, tvb, and Na^+/H^+ exchange 1(chNHE1) genes, which are the specific receptors for ALV subgroups A, B, and J, respectively.Conclusions: Simultaneous editing of multiple receptors to block infection by different subgroups of ALV confirmed that ALV subgroups A, B, and J do not share host receptors. This strategy could be used to generate cells resistant to multiple viral pathogens that use distinct receptors for cell entry. | Hong Jo Lee Kyung Je Park Kyung Youn Lee Yongxiu Yao Venugopal Nair Jae Yong Han | 2019 | Journal of Animal Science and Biotechnology2019，10，2： | 3 |
| 4 | Knockdown of β-catenin controls both apoptotic and autophagic cell death through LKB1/AMPK signaling in head and neck squamous cell carcinoma cell lines显示文摘 | Hyo Won Chang Yoon Se Lee Hae Yun Nam MyoungWol Han Hyo Jung Kim So Young Moon HyesungJeon Jung Je Park Thomas E. Carey Sung Eun Chang Seong Who Kim Sang Yoon Kim | 2012 | Cellular Signalling2012，，： | 2 |
| 5 | Human amnion-derivedmesenchymal stemcells are a potential source foruterine stemcell therapy显示文摘 | Han K Lee JE Kwon SJ | 2008 | Cell Prolif2008，41，5： | 1 |
| 6 | Characteristic analysis of electrodynamic suspension device with permanent magnet Halbach array显示文摘 | Han W C Hyung S H Je S B | | 0，，7： | 1 |
| 7 | Recent studies in turbine blade cooling显示文摘 | HAN JE CHIN | 2004 | Inter- national Journal of Rotating Machinery2004，10，6： | 1 |
| 8 | Degradation of methylene blue via photocatalysis of titanium dioxide显示文摘 | Chul Han Kwon Hyunmin Shin Je Hun Kim | 2004 | Materials Chemistry and Physics2004，86，： | 1 |
| 9 | Preparation and characterization of TiO2-SiO2 nano - composite thin films 显示文摘 | Chul Han Kwon Je Hun Kim | 2003 | Ceramics International2003，29，8： | 1 |
| 10 | Cancer in patients on chronic dialysis in Korea显示文摘 | Lee JE Han SH ChoBC | 2009 | J Korean Med Sci2009，24，： | 1 |
| 11 | Zn-doped nickel iron(oxy)hydroxide nanocubes passivated by polyanions with high catalytic activity and corrosion resistance for seawater oxidation显示文摘Electrochemical water splitting to produce hydrogen fuel is a promising renewable energy-conversion technique.Large-scale electrolysis of freshwater may deplete water resources and cause water scarcity worldwide.Thus,seawater electrolysis is a potential solution to the future energy and water crisis.In seawater electrolysis,it is critical to develop cost-effective electrocatalysts to split seawater without chloride corrosion.Herein,we present zinc-doped nickel iron(oxy)hydroxide nanocubes passivated by negatively charged polyanions(NFZ-PBA-S)that exhibits outstanding catalytic activity,stability,and selectivity for seawater oxidation.Zn dopants and polyanion-rich passivated surface layers in NFZ-PBA-S could effectively repel chlorine ions and enhance corrosion resistance,enabling its excellent catalytic activity and stability for seawater oxidation. | So Jung Kim Heechae Choi Jeong Ho Ryu Kang Min Kim Sungwook Mhin Arpan Kumar Nayak Junghwan Bang Minyeong Je Ghulam Ali Kyung Yoon Chung Kyeong-Han Na Won-Youl Choi Sunghwan Yeo Jin Uk Jang HyukSu Han | 2023 | Journal of Energy Chemistry2023，，6： | 1 |
| 12 | Paclitaxel:a review of adverse toxicities and novel delivery strateies显示文摘 | Marupudi NI Han JE Li KW | | 0，，05： | 1 |
| 13 | Paclitaxel:a review of adverse toxicities and novel delivery strateies显示文摘 | Marupudi NI Han JE Li KW | 2007 | Expert Opin Dru Saf2007，6，5： | 1 |
| 14 | Evolution of polymer blend morphology during compounding in twin -screw extruder显示文摘 | Je Kyum Lee Chang Dae Han | 2000 | Polymer2000，41，5： | 1 |
| 15 | High sensitivity C-reactive pro- tein and its relationship with impaired glucose regulation in lean patients with polycystic ovary syndrome 显示文摘 | Kim JW Han JE Kim YS | 2011 | Gynecol Endocrinol2011，28，4： | 1 |
| 16 | Degradation of methylene blue via photocatalysis of titanium dioxide显示文摘 | Chul Han Kwon Hyunmin Shin Je Hun Kim | 2004 | Materials Chemistry and Physics2004，86，1： | 1 |
| 17 | Correlates of self - care behaviors for managing hypertension among Korean Americans : a questionnaire survey显示文摘 | Lee JE HAN HR SONG H | 2010 | Int J Nuts Stud2010，47，4： | 1 |
| 18 | Vitamin E inhibition on plate-let procoagulant activity:involvement of aminophospholipid translocase activity显示文摘 | Kim JE Han M Hanl KS | 2011 | Thromb Res2011，127，5： | 1 |
| 19 | Relationship between en- dometrial and subendometrial blood flow measured by three-di- mensional power doppler ultrasound and pregnancy after in- trauterine insemination显示文摘 | KIM A HAN JE YOON TK | 2010 | Fertility and Sterility2010，94，2： | 1 |
| 20 | Clinical efficacy of sublingual immunotherapy in pediatric patients with allergic rhinitis sensitized to house dust mites:comparison to adult patients 显示文摘 | Han DH Choi YS Lee JE | 2012 | Acta Otolaryngol2012，1321，： | 1 |
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