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| 1 | CD24 expression predicts distant metastasis in extrahepatic bile duct cancer显示文摘AIM: To evaluate the prognostic significance of CD24 expression in patients undergoing adjuvant chemoradiotherapy for extrahepatic bile duct (EHBD) cancer. METHODS: Eighty-four patients with EHBD cancer who underwent curative resection followed by adjuvant chemoradiotherapy were enrolled in this study. Postoperative radiotherapy was delivered to the tumor bed and regional lymph nodes up to a median of 40 Gy (range: 40-56 Gy). All patients also received fluoropyrimidine chemotherapy for radiosensitization during radiotherapy. CD24 expression was assessed with immunohistochemical staining on tissue microarray. Clinicopathologic factors as well as CD24 expression were evaluated in multivariate analysis for clinical outcomes including loco-regional recurrence, distant metastasisfree and overall survival. RESULTS: CD24 was expressed in 36 patients (42.9%). CD24 expression was associated with distant metastasis, but not with loco-regional recurrence nor with overall survival. The 5-year distant metastasis-free survival rates were 55.1% and 29.0% in patients with negative and positive expression, respectively (P=0.0100). On multivariate analysis incorporating N stage, histologic differentiation and CD24 expression, N stage was the only significant factor predicting distant metastasis-free survival (P=0.0089), while CD24 expression had borderline significance (P=0.0733). In subgroup analysis, CD24 expression was significantly associated with 5-year distant metastasis-free survival in node-positive patients (38.4% with negative expression vs 0% with positive expression, P=0.0110), but not in nodenegative patients (62.0% with negative expression vs 64.0% with positive expression,P=0.8599). CONCLUSION: CD24 expression was a significant predictor of distant metastasis for patients undergoing curative resection followed by adjuvant chemoradiotherapy especially for node-positive EHBD cancer. | Kyubo Kim Hye Sook Min Eui Kyu Chie Jin-Young Jang Sun Whe Kim Sae-Won Han Do-Youn Oh Seock-Ah Im Tae-You Kim Yung-Jue Bang Ja-June Jang Sung W Ha | 2013 | World Journal of Gastroenterology2013，19，9： | 2 |
| 2 | ERCC1 expression by immunohistochemistry and EGFR mutations in resected non-small cell lung cancer显示文摘 | LEE K H MIN H S HANS W | 2008 | Lung Cancer2008，60，3： | 1 |
| 3 | Evaluation of the effects ofpulse high - volume hemofiltration in patients with severe sepsis : apreliminary study显示文摘 | Peng Z Pai P Han Min W | 2010 | Int J Artif Organs2010，33，8： | 1 |
| 4 | ERCC1 expression by immunohistochemisu7 and EGFR mutations in resected non-small cell lung cancer显示文摘 | LEE K H MIN H S HANS W | 2008 | Lung Cancer2008，60，40： | 1 |
| 5 | Improved video compression efficiency through flexible unit representation and corresponding extension of coding tools显示文摘 | HAN W J MIN J LEE T | 2010 | IEEE Transactions on Circuits and Systems for Video Technology2010，20，12： | 1 |
| 6 | Draft genome of the kiwifruit Actinidia chinensis 显示文摘 | Huang SX Ding J Deng DJ Tang W Sun HH Liu DY Zhang L Niu XL Zhang X Meng M Yu JD Liu J Han Y Shi W Zhang DF Cao SQ Wei ZJ Cui YL Xia YH Zeng HP Bao K Lin L Min Y Zhang H Miao M Tang XF Zhu YZ Sui Y Li GW Sun HJ Yue JY Sun JQ Liu FF Zhou LQ Lei L Zheng XQ Liu M Huang L Song J Xu CH Li JW Ye KY Zhong SL Lu BR He GH Xiao FM Wang HL Zheng HK Fei ZJ Liu YS | 2013 | Nat Commun2013，4，： | 1 |
| 7 | Block partitioning struc ture in the HEVC standard显示文摘 | Kim I Min J Han W | 2012 | Circuits and Systems for Video Technology IEEE Transactions on2012，2，12： | 1 |
| 8 | Evaluation of the effects of pulse high - volume hemofihration in patients with severe sepsis: a prelimi- nary study显示文摘 | Peng Z Pai P Han - Min W | 2010 | Int JArtifOrgans2010，33，8： | 1 |
| 9 | Capsaicin inhibits in vitro and in vivo angiogenesis显示文摘 | Min J K Han K Y Kim E C Kim Y M Lee S W Kim O K Kim K W Gho Y S Kwon Y G | | 0，，： | 1 |
| 10 | Improvement of cadmium ion removal by base treatment of juniper fiber显示文摘 | Min S Han J S Shin E W | | 0，，05： | 1 |
| 11 | Graphene oxide sheath on Ag nanoparticle/graphene hybrid films as an antioxidatlve coating and enhancer of surface-enhanced Raman scattering 显示文摘 | KIM Y K HANS W MIN D H | 2012 | ACS Applied Materials & Interfaces2012，4，12： | 1 |
| 12 | Evaluation of the effects of pulse high- volume hemofitration in patients with severe sepsis:a preliminary study显示文摘 | Peng Z Pai P Han Min W | 2010 | Int J Artif Organs2010，33，8： | 1 |
| 13 | Improved video compression efficiency through flexible unit representation and corresponding extension of coding tools显示文摘 | Han W Min J Kim I K | 2010 | IEEE Transactions on Circuits and Systems for Video Technology2010，20，12： | 1 |
| 14 | Construction of an integrated pepper map using RFLP,SSR,CAPS,AFLP,WRKY,rRAMP,and BAC end sequences显示文摘 | Lee H R Bae I H Park S W Kim H J Min W K Han J H Kim K T Kim B D | | 0，，： | 1 |
| 15 | Reverse random amplified microsatellite polymorphism reveals enhanced polymorphisms in the 3i(a) end of simple sequence repeats in the pepper genome显示文摘 | Min W K Han J H Kang W H | | 0，，： | 1 |
| 16 | Acs Appl Mater Interfaces显示文摘 | Kim Y K Han S W Min D H | 2012 | 4(12): 65452012，4，12： | 1 |
| 17 | Ceiling-based visual posi- tioning for an indoor mobile robot with monocular vision 显示文摘 | Xu D Han L W Min T | 2009 | IEEE Transactions on Industrial Electronics2009，56，05： | 1 |
| 18 | Chemical bath deposi- tion of CdS quantum dots on vertically aligned ZnO nanorods for quantum dots-sensitized solar cells 显示文摘 | LEE W MIN S K HANS H | 2009 | Electrochemistry Communications2009，11，1： | 1 |
| 19 | Initial Experiences with Laparoscopy-assisted and Total Laparoscopy for Anatomical Liver Resection:a Preliminary Study显示文摘 | Min S K Han H S Kim S W | 2006 | J Korean Med Sci2006，21，1： | 1 |
| 20 | Effects of organic solvents on the structure stability of TS-1 for the ammoximation of cyclohexanone 显示文摘 | WU C WANG Y MI Z XUE L WU W MIN E HAN S HE F FU S | 2002 | React Kinet Catal Lett2002，77，1： | 1 |
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