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| 1 | Asymptomatic patients and asymptomatic phases of Coronavirus Disease 2019(COVID-19):a population-based surveillance study显示文摘In this population-based study,we identified 307 confirmed COVID-19 cases from massive surveillance,including 129551 individuals screened at fever clinics or returning from Hubei and 3710 close contacts of confirmed COVID-19 patients.Among them,17 patients were asymptomatic at initial clinical assessment.These asymptomatic patients on admission accounted for a small proportion of all patients(5.54%)with relatively weak transmissibility,and the detection rate was 0.35 per 100 close contacts.Moreover,the dynamics of symptoms of the 307 patients showed that the interval from symptom remission to the final negativity of viral nucleic acid was 5.0 days(interquartile range 2.0 to 11.0 days),with 14 patients(4.56%)having re-detectable viral RNA after discharge.Overall;our findings suggested asymptomatic carriers and presymptomatic patients only accounted for a small proportion of COVID-19 patients.Also,the asymptomatic phase during recovery from COVID-19 implied that negativity in viral RNA is necessary as a de-isolation criterion and follow-up is recommended. | Xueying Zheng Sihui Luo Yong Sun Mingfeng Han Jian Liu Liangye Sun Liangming Zhang Ping Ling Yu Ding Tengchuan Jin Zhirong Liu Jianping Weng | 2020 | National Science Review2020，7，10： | 2 |
| 2 | Coverage and energy consumption control in mobile heterogeneous wireless sensor networks显示文摘 | Wang Xinbing Han Sihui Wu Yibo | 2013 | IEEE Trans on Automatic Control2013，58，4： | 1 |
| 3 | The zinc finger transcription factor,KLF2,protects against COVID-19 associated endothelial dysfunction显示文摘Coronavirus disease 2019(COVID-19)is regarded as an endothelial disease(endothelialitis)with its patho-mechanism being incompletely understood.Emerging evidence has demonstrated that endothelial dysfunction precipitates COVID-19 and its accompanying multi-organ injuries.Thus,pharmacotherapies targeting endothelial dysfunction have potential to ameliorate COVID-19 and its cardiovascular complications.The objective of the present study is to evaluate whether kruppel-like factor 2(KLF2),a master regulator of vascular homeostasis,represents a therapeutic target for C0VID-19-induced endothelial dysfunction.Here,we demonstrate that the expression of KLF2 was reduced and monocyte adhesion was increased in endothelial cells treated with COVID-19 patient serum due to elevated levels of pro-adhesive molecules,ICAM1 and VCAM1.IL-1β and TNF-α;two cytokines elevated in cytokine release syndrome in COVID-19 patients,decreased KLF2 gene expression.Pharmacologic(atorvastatin and tannic acid)and genetic(adenoviral overexpression)approaches to augment KLF2 levels attenuated COVID-19-serum-induced increase in endothelial inflammation and monocyte adhesion.Next-generation RNA-sequencing data showed that atorvastatin treatment leads to a cardiovascular protective transcriptome associated with improved endothelial function(vasodilation,antiinflammation,antioxidant status,anti-thrombosis/-coagulation,anti-fibrosis,and reduced angiogenesis).Finally,knockdown of KLF2 partially reversed the ameliorative effect of atorvastatin on COVID-19-serum-induced endothelial inflammation and monocyte adhesion.Collectively,the present study implicates loss of KLF2 as an important molecular event in the development of COVID-19-induced vascular disease and suggests that efforts to augment KLF2 levels may be therapeutically beneficial. | Suowen Xu Yujie Liu Yu Ding Sihui Luo Xueying Zheng Xiumei Wu Zhenghong Liu Iqra Ilyas Suyu Chen Shuxin Han Peter J.Little Mukesh K.Jain Jianping Weng | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 1 |
| 4 | A Distributed-Centralized Scheme for Short- and Long-Term Spectrum Sharing with a Random Leader in Cognitive Radio Networks显示文摘 | LIANG Qingkai HAN Sihui YANG Feng et at | 2012 | IEEE Journal on Selected Areas of Communications2012，30，11： | 1 |
| 5 | Research on the Present Situation, Problems and Countermeasures of China s Marine Talent Ecosphere显示文摘The present situation of China s marine talent ecosphere was studied firstly,and then problems in China s marine talent ecosphere were analyzed.Finally,some countermeasures for the construction of China s marine talent ecosphere were put forward. | Sihui HAN Qunzhen QU | 2020 | Meteorological and Environmental Research2020，11，6： | 0 |
| 6 | Research on Management of Marine Science and Technology Talent Ecological Chain显示文摘Firstly,the current situation of China’s current marine science and technology talent ecological chain was analyzed,and then the problems in talent training were discussed.Finally,countermeasures to improve the talent ecological chain were proposed. | Sihui HAN Qunzhen QU | 2021 | Meteorological and Environmental Research2021，12，2： | 0 |
| 7 | Research on Current Situation,Problems and Countermeasures of Marine Logistics Talent Training in the Postepidemic Era显示文摘The current situation of China’s marine logistics talents was studied firstly,and then problems in China’s marine logistics talent training were analyzed.Finally,some countermeasures for optimizing the training of marine logistics talents were proposed according to the problems. | Qunzhen QU Sihui HAN | 2021 | Meteorological and Environmental Research2021，12，2： | 0 |
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