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| 1 | Leucyl-tRNA Synthetase Is an IntraceUular Leucine Sensor for the mTORCl-Signaling Path- way 显示文摘 | HANJ M JEONG S J PARK M C | 2012 | Cell2012,149,: | 1 |
| 2 | Detection of hypervascular nodular hepatocellur carcinomas: value of triphasiehelical CT compared with iodizedoil CT 显示文摘 | CHOIB I LEEH J HANJ K | 2010 | AJR2010,157,2: | 1 |
| 3 | Optical parameters of NaY(WO4)2 crystals doped with Pr and Ho显示文摘 | CHENG Z X ZHANG S J HANJ R | 2001 | Cryst Res Technol2001,36,45: | 1 |
| 4 | Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORCl-signaling pathway 显示文摘 | HANJ M JEONG S J PARK M C | 2012 | Cell2012,149,2: | 1 |
| 5 | Long-term outcomes of a 5-year follow up of patients with immune thrombocytopenic purpura after splenectomy显示文摘 | HanJ J Baek SK Lee JJ | 2010 | Korean J Hematol2010,45,3: | 1 |
| 6 | Onshore wind power development in China: challenges behind a successful story 显示文摘 | HANJ Y MOL A P J LU Y L | 2009 | Energy Policy2009,,37: | 1 |
| 7 | Clinicopathologic analysis of ocular adnexal lymphomas: extranodal marginal zone B-cell lymphoma constitutes the vast majority of ocular lymphomas among Koreans and affect younger patients显示文摘 | Cho EY HanJ J Ree HJ et at | 2003 | AmJ Hematol2003,73,2: | 1 |
| 8 | Texture evolution of thestrip cast 1050Al alloy processed by continuous confined strip shearingand its formability evoluation显示文摘 | HanJ H Seak H K Chung Y H Shin M C Lee J C | 2002 | Mater Sci Eng A2002,,323: | 1 |
| 9 | Detection of pervascular nodular hepato- cellur carcinomas:value of triphasic helical CT compared withiodizedoil CT显示文摘 | Choibi L Leeh J Hanj K | 2012 | A JR2012,157,2: | 1 |
| 10 | Cidea is associated with lipid droplets and insulin sensitivity in humans显示文摘 | Puri V HanJ Jt S Konda S Nicoloro SM Straubbaa Chawla A | 2008 | P Nat! Acad Sci USA2008,105,22: | 1 |
| 11 | Design and Field Emission Test of Carbon Nanotube Pasted Cathodes Travelling Wave Tube Applications 显示文摘 | Kim H J ChoiJJ HanJ He etal | 2006 | IEEE Trans on Electron Devices2006,53,11: | 1 |
| 12 | Brassinosteroids alleviate chilling-induced oxidative damage by enhancing antioxidant defense system in suspension cultured cells of Chorispora bungeana 显示文摘 | Liu Y J ZhaoZ G SiJ DiC X HanJ An LZ | 2009 | Plant Growth Regulation2009,59,3: | 1 |
| 13 | Paracentesis in cirrhotics is associated with increased risk of 30-day readmission显示文摘AIM To determine the readmission rate, its reasons, predictors, and cost of 30-d readmission in patients with cirrhosis and ascites.METHODS A retrospective analysis of the nationwide readmission database(NRD) was performed during the calendar year 2013. All adults cirrhotics with a diagnosis of ascites,spontaneous bacterial peritonitis, or hepatic encephalopathy were identified by ICD-9 codes. Multivariate analysis was performed to assess predictors of 30-d readmission and cost of readmission.RESULTS Of the 59597 patients included in this study, 18319(31%) were readmitted within 30 d. Majority(58%) of readmissions were for liver related reasons. Paracentesis was performed in 29832(50%) patients on index admission. Independent predictors of 30-d readmission included age < 40(OR: 1.39; CI: 1.19-1.64), age 40-64(OR: 1.19; CI: 1.09-1.30), Medicaid(OR: 1.21; CI: 1.04-1.41) and Medicare coverage(OR: 1.13; CI: 1.02-1.26), > 3 Elixhauser comorbidity(OR: 1.13; CI: 1.05-1.22), nonalcoholic cirrhosis(OR: 1.16; CI: 1.10-1.23), paracentesis on index admission(OR: 1.28; CI: 1.21-1.36) and having hepatocellular carcinoma(OR: 1.21; CI: 1.05; 1.39). Cost of index admission was similar in patients readmitted and not readmitted(P-value: 0.34); however cost of care was significantly more on 30 d readmission($30959 ± 762) as compared to index admission($12403 ± 378), P-value: < 0.001.CONCLUSION Cirrhotic patients with ascites have a 33% chance of readmission within 30-d. Younger patients, with public insurance, nonalcoholic cirrhosis and increased comorbidity who underwent paracentesis are at increased risk of readmission. Risk factors for unplanned readmission should be targeted given these patients have higher healthcare utilization. | Lindsay A Sobotka Rohan M Modi Akshay Vijayaraman A James Hanje Anthony J Michaels Lanla F Conteh Alice Hinton Ashraf El-Hinnawi Khalid Mumtaz | 2018 | World Journal of Hepatology2018,10,6: | 1 |
| 14 | Thalidomide-induced severe hepatotoxieity显示文摘 | Hanje A J Shamp JL Thomas FB | 2006 | Pharmaeotherapy2006,26,7: | 1 |
| 15 | Load-deflection response of transversely isotropic piles under lateral loads 显示文摘 | HANJ FROST J D | 2000 | International Journalfro Numerical and Analytical Methods in Geo-mechanics2000,24,5: | 1 |
| 16 | Cranial neural crest derived mesenchymal proliferation is regulated by MSX1-mediated p19(INK4d) expression during odonto-genesis 显示文摘 | HanJ Ito Y Yeo J Y | 2003 | DevBiol2003,261,1: | 1 |
| 17 | Diagnosis of morbid obesity may not impact healthcare utilization for orthotopic liver transplantation:A propensity matched study显示文摘AIM To study mortality, length of stay, and total charges in morbidly obese adults during index hospitalization for orthotopic liver transplantation.METHODS The Nationwide Inpatient Sample was queried to obtain demographics, healthcare utilization, post orthotopic liver transplantation(OLT) complications, and short term outcomes of OLT performed from 2003 to 2011(n = 46509). We divided patients into those with [body mass index(BMI) ≥ 40] and without(BMI < 40) morbid obesity. Multivariable logistic regression analysis was performedto characterize differences in in-hospital mortality, length of stay(LOS), and charges for OLT between patients with and without morbid obesity after adjusting for significant confounders. Additionally, propensity matching was performed to further validate the results.RESULTS Of the 46509 patients who underwent OLT during the study period, 818(1.8%) were morbidly obese. Morbidly obese recipients were more likely to be female(46.8% vs 33.4%, P = 0.002), Caucasian(75.2% vs 67.8%, P = 0.002), in the low national income quartile(32.3% vs 22.5%, P = 0.04), and have ≥ 3 comorbidities(modified Elixhauser index; 83.9% vs 45.0%, P < 0.001). Morbidly obese patient also had an increase in procedure related hemorrhage(P = 0.028) and respiratory complications(P = 0.043). Multivariate and propensity matched analysis showed no difference in mortality(OR: 0.70; 95%CI: 0.27-1.84, P = 0.47), LOS(β:-4.44; 95%CI:-9.93, 1.05, P = 0.11) and charges for transplantation(β: $15693; 95%CI:-51622-83008, P = 0.64) between the two groups. Morbidly obese patients were more likely to have transplants on weekdays(81.7%) as compared to those without morbid obesity(75.4%, P = 0.029).CONCLUSION Morbid obesity may not impact in-hospital mortality and health care utilization in OLT recipients. However, morbidly obese patients may be selected after careful assessment of co-morbidities. | Joshua R Peck Nicholas Latchana Anthony Michaels Adam J Hanje Alice Hinton Elmahdi A Elkhammas Sylvester M Black Khalid Mumtaz | 2017 | World Journal of Hepatology2017,9,12: | 0 |
| 18 | Effect of transplant center volume on post-transplant survival in patients listed for simultaneous liver and kidney transplantation显示文摘AIM To examine the effect of center size on survival differences between simultaneous liver kidney transplantation(SLKT) and liver transplantation alone(LTA) in SLKT-listed patients.METHODS The United Network of Organ Sharing database was queried for patients ≥ 18 years of age listed for SLKT between February 2002 and December 2015. Posttransplant survival was evaluated using stratified Cox regression with interaction between transplant type(LTA vs SLKT) and center volume.RESULTS During the study period, 393 of 4580 patients(9%) listed for SLKT underwent a LTA. Overall mortality was higher among LTA recipients(180/393, 46%) than SLKT recipients(1107/4187, 26%). The Cox model predicted a significant survival disadvantage for patients receiving LTA vs SLKT [hazard ratio, hazard ratio(HR) = 2.85; 95%CI: 2.21, 3.66; P < 0.001] in centers performing 30 SLKT over the study period. This disadvantage was modestly attenuated as center SLKT volume increased, with a 3% reduction(HR = 0.97; 95%CI: 0.95, 0.99; P = 0.010) for every 10 SLKs performed.CONCLUSION In conclusion, LTA is associated with increased mortality among patients listed for SLKT. This difference is modestly attenuated at more experienced centers and may explain inconsistencies between smaller-center and larger registry-wide studies comparing SLKT and LTA outcomes. | Rohan M Modi Dmitry Tumin Andrew J Kruger Eliza W Beal Don Hayes Jr James Hanje Anthony J Michaels Kenneth Washburn Lanla F Conteh Sylvester M Black Khalid Mumtaz | 2018 | World Journal of Hepatology2018,10,1: | 0 |
| 19 | Impact of transjugular intrahepatic porto-systemic shunt on post liver transplantation outcomes: Study based on the United Network for Organ Sharing database显示文摘AIM To determine the impact of transjugular intrahepatic porto-systemic shunt(TIPS) on post liver transplantation(LT) outcomes.METHODS Utilizing the United Network for Organ Sharing(UNOS) database, we compared patients who underwent LT from 2002 to 2013 who had underwent TIPS to those without TIPS for the management of ascites while on the LT waitlist. The impact of TIPS on 30-d mortality, length of stay(LOS), and need for re-LT were studied. For evaluation of mean differences between baseline characteristics for patients with and without TIPS, we used unpaired t-tests for continuous measures and χ~2 tests for categorical measures. We estimated the impact of TIPS on each of the outcome measures. Multivariate analyses were conducted on the study population to explore the effect of TIPS on 30-d mortality post-LT, need for re-LT and LOS. All covariates were included in logistic regression analysis.RESULTS We included adult patients(age ≥ 18 years) who underwent LT from May 2002 to September 2013. Only those undergoing TIPS after listing and before liver transplant were included in the TIPS group. We excluded patients with variceal bleeding within two weeks of listing for LT and those listed for acute liver failure or hepatocellular carcinoma. Of 114770 LT in the UNOS database, 32783(28.5%) met inclusion criteria. Of these 1366(4.2%) had TIPS between the time of listing and LT. We found that TIPS increased the days on waitlist(408 ± 553 d) as compared to those without TIPS(183 ± 330 d), P < 0.001. Multivariate analysis showed that TIPS had no effect on 30-d post LT mortality(OR = 1.26; 95%CI: 0.91-1.76) and re-LT(OR = 0.61; 95%CI: 0.36-1.05). Pre-transplant hepatic encephalopathy added 3.46 d(95%CI: 2.37-4.55, P < 0.001), followed by 2.16 d(95%CI: 0.92-3.38, P = 0.001) by TIPS to LOS. CONCLUSION TIPS did increase time on waitlist for LT. More importantly, TIPS was not associated with 30-d mortality and re-LT, but it did lengthen hospital LOS after transplantation. | Khalid Mumtaz Sherif Metwally Rohan M Modi Nishi Patel Dmitry Tumin Anthony J Michaels James Hanje Ashraf El-Hinnawi Don Hayes Jr Sylvester M Black | 2017 | World Journal of Hepatology2017,9,2: | 0 |