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您的检索式：作者名="Hanan Soliman"
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| 1 | Antioxidant Effect of Sepia Ink Extract on Extrahepatic Cholestasis Induced by Bile Duct Ligation in Rats显示文摘Objective The aim of our study was to assess the complications of hepatic fibrosis associated with bile duct ligation and the potential curative role of sepia ink extract in hepatic damage induced by bile duct ligation. Methods Rattus norvegicus rats were divided into 3 groups: Sham-operated group, model rats that underwent common bile duct ligation(BDL), and BDL rats treated orally with sepia ink extract(200 mg/kg body weight) for 7, 14, and 28 d after BDL. Results There was a significant reduction in hepatic enzymes, ALP, GGT, bilirubin levels, and oxidative stress in the BDL group after treatment with sepia ink extract. Collagen deposition reduced after sepia ink extract treatment as compared to BDL groups, suggesting that the liver was repaired. Histopathological examination of liver treated with sepia ink extract showed moderate degeneration in the hepatic architecture and mild degeneration in hepatocytes as compared to BDL groups. Conclusion Sepia ink extract provides a curative effect and an antioxidant capacity on BDL rats and could ameliorate the complications of liver cholestasis. | Hanan Saleh Amel M Soliman Ayman S Mohamed Mohamed-Assem S Marie | 2015 | Biomedical and Environmental Sciences2015，28，8： | 6 |
| 2 | Su1543 A Prospective Random- ized Comparative Study of Endoscopic Band Ligation and Sclerotherapy of Bleeding Internal Hemorrhoids in Egyptian Patients With Liver Cirrhosis 显示文摘 | Atif Awad Hanan Soliman Sabry Abou Sail at al | 2011 | Gastrointesti nal Endoscopy2011，73，4： | 1 |
| 3 | Assessment of hepatic fibrosis in pediatric cases with hepatitis C virus in Egypt显示文摘AIM: To assess hepatic fibrosis and factors associated with its progression in children with HCV infection. METHODS: At the Hepatology Unit,Cairo University Children's Hospital,a single liver biopsy was performed to 43 children with HCV infection after an informed consent between 1998-2004. Their mean age at liver biopsy was 8.67 ± 4.3 years. RESULTS: Among the 43 patients' biopsies,12 (27.9%) were having no fibrosis,20 (46.5%) mild fibrosis and 11 (25.6%) moderate to severe fibrosis. The median time for development of fibrosis was estimated to be 5.5 years. Developing fibrosis was significantly associated with shorter duration from first detected ALT elevation to biopsy (12 mo vs 1.2 mo,P = 0.015) and having higher levels of direct serum bilirubin (0.3 mg/dL vs 0.5 mg/dL,P = 0.048). No association was found between fibrosis stage and the presence of co-morbid conditions (P = 0.33). CONCLUSION: Hepatic fibrosis was present in 72.1% of children with HCV infection. The development of fibrosis was associated with higher levels of direct serum bilirubin. There was no significant association between fibrosis and age,duration of infection,risk factors,co-morbid conditions and most biochemical parameters. | Manal A El-Hawary Mona S El-Raziky Gamal Esmat Hanan Soliman Amr Abouzied Maissa El-Raziky Wafaa El-Akel Rokaya El-Sayed Fatma Shebl Abdel Aziz Shaheen Hanaa El-Karaksy | 2007 | World Journal of Gastroenterology2007，13，20： | 1 |
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