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| 1 | Chinese stalagmite paleoclimate researches: A review and perspective显示文摘Stalagmite is one kind of secondary carbonates formed in limestone caves(speleothem). After cave water droplets containing Ca2+and HCO3 drip onto floor, carbonate in the water might become supersaturated due to CO2 degassing under certain conditions, resulting in the formation of stalagmite in a process year after year. Stalagmite is one of important geological archives for paleoclimate research. The advantages include wide spatial distribution, suitable for U-Th and U-Pb dating, enriched in climate proxies, continuity, long time span, comparability and lower sampling cost etc. These factors have propelled stalagmite paleoclimate research to the forefront of global paleoclimatology with an irreplaceable role. The stalagmite paleoclimate study started in the western countries, mainly in Europe and America in 1960 s–1970 s, while the relevant research in China was progressively developed in the 1980 s–1990 s after the Reform and Opening up. Although there was a huge gap between the overall research level in China and western countries, a solid research foundation, as well as a number of talent teams were established during the period. In the 21 st century, starting from the publication of stalagmite records from Hulu Cave in Nanjing in 2001, the stalagmite paleoclimate research in China has ushered in a flourishing development and a real leap on the basis of international cooperation, resulting in significant international impacts. The landmark achievements, including establishment of the world’s longest(640000 years) East Asian monsoon stalagmite record, as well as the longest Indian monsoon(280000 years),South American monsoon(250000 years), North American westerly climate(330000 years), Central Asian westerly climate(135000 years), and northwestern China westerly climate(500000 years), have laid a milestone in the paleoclimate study in these climate domains. Importantly, these stalagmite records have revealed the relationship of Asian monsoon variations with solar insolation climate change in polar regions, and the South American monsoon changes on orbital-suborbital timescales, which have provided new geological observations for the development of orbital-suborbital climate theory;elaborated coupling and differentiation relationships between the Asian monsoon and the westerly climate;reconstructed the history of Asian monsoon changes in the Holocene in detail, and thus the hydrological and climate variances behind Chinese and Indian civilizationcultural evolutions. Furthermore, a large number of high-resolution stalagmite records over the past 2000 years have been reconstructed, which are important for understanding short-term climate variability and magnitude, events, cycles, and thus the future climate projection. The achievements have also involved the improvements of a number of important techniques, such as U-Th dating method, the establishments of various hydroclimatic proxies, as well as the contributions to the reconstruction of the atmosphere14C variation history over the past ~54000 years. On the perspective of the future, the Chinese stalagmite community should continue to develop key techniques, further clarify the hydroclimatic significance of stalagmite proxies, impel the integration of related disciplines, and concentrate on key scientific issues in global climate change and major social demands. | Hai CHENG Haiwei ZHANG Jingyao ZHAO Hanying LI Youfeng NING Gayatri KATHAYAT | 2019 | Science China Earth Sciences2019，62，10： | 17 |
| 2 | Identifcation of large-scale goaf instability in underground mine using particle swarm optimization and support vector machine显示文摘An approach which combines particle swarm optimization and support vector machine(PSO–SVM)is proposed to forecast large-scale goaf instability(LSGI).Firstly,influencing factors of goaf safety are analyzed,and following parameters were selected as evaluation indexes in the LSGI:uniaxial compressive strength(UCS)of rock,elastic modulus(E)of rock,rock quality designation(RQD),area ration of pillar(Sp),the ratio of width to height of the pillar(w/h),depth of ore body(H),volume of goaf(V),dip of ore body(a)and area of goaf(Sg).Then LSGI forecasting model by PSO-SVM was established according to the influencing factors.The performance of hybrid model(PSO+SVM=PSO–SVM)has been compared with the grid search method of support vector machine(GSM–SVM)model.The actual data of 40 goafs are applied to research the forecasting ability of the proposed method,and two cases of underground mine are also validated by the proposed model.The results indicated that the heuristic algorithm of PSO can speed up the SVM parameter optimization search,and the predictive ability of the PSO–SVM model with the RBF kernel function is acceptable and robust,which might hold a high potential to become a useful tool in goaf risky prediction research. | Zhou Jian Li Xibing Hani S.Mitri Wang Shiming Wei Wei | 2013 | International Journal of Mining Science and Technology2013，23，5： | 14 |
| 3 | Orbital-scale Asian summer monsoon variations:Paradox and exploration显示文摘The Asian summer monsoon(ASM) is a vast climate system, whose variability is critical to the livelihoods of billions of people across the Asian continent. During the past half-century, much progress has been made in understanding variations on a wide range of timescales, yet several significant issues remain unresolved. Of note are two long-standing problems concerning orbital-scale variations of the ASM.(1) Chinese loess magnetic susceptibility records show a persistent glacial-interglacial dominated ~100 kyr(thousand years) periodicity, while the cave oxygen-isotope(δ18 O) records reveal periodicity in an almost pure precession band(~20 kyr periodicity)—the 'Chinese 100 kyr problem'.(2) ASM records from the Arabian Sea and other oceans surrounding the Asian continent show a significant lag of 8–10 kyr to Northern Hemisphere summer insolation(NHSI), whereas the Asian cave δ18 O records follow NHSI without a significant lag—a discrepancy termed the 'sea-land precession-phase paradox'. How can we reconcile these differences? Recent and more refined model simulations now provide spatial patterns of rainfall and wind across the precession cycle, revealing distinct regional divergences in the ASM domain, which can well explain a large portion of the disparities between the loess, marine, and cave proxy records. Overall, we also find that the loess, marine, and cave records are indeed complementary rather than incompatible, with each record preferentially describing a certain aspect of ASM dynamics. Our study provides new insight into the understanding of different hydroclimatic proxies and largely reconciles the 'Chinese 100 kyr problem' and 'sea-land precession-phase paradox'. | Hai CHENG Haiwei ZHANG Yanjun CAI Zhengguo SHI Liang YI Chenglong DENG Qingzhen HAO Youbing PENG Ashish SINHA Hanying LI Jingyao ZHAO Ye TIAN Jonathan BAKER Carlos PEREZ-MEJIAS | 2021 | Science China Earth Sciences2021，64，4： | 6 |
| 4 | A rapid and accurate direct measurement method of underground coal seam gas content based on dynamic diffusion theory显示文摘Coal seam gas content is frequently measured in quantity during underground coal mining operation and coalbed methane(CBM)exploration as a significant basic parameter.Due to the calculation error of lost gas and residual gas in the direct method,the efficiency and accuracy of the current methods are not inadequate to the large area multi-point measurement of coal seam gas content.This paper firstly deduces a simplified theoretical dynamic model for calculating lost gas based on gas dynamic diffusion theory.Secondly,the effects of various factors on gas dynamic diffusion from coal particle are experimentally studied.And sampling procedure of representative coal particle is improved.Thirdly,a new estimation method of residual gas content based on excess adsorption and competitive adsorption theory is proposed.The results showed that the maximum error of calculating the losing gas content by using the new simplified model is only 4%.Considering the influence of particle size on gas diffusion law,the particle size of the collected coal sample is below 0.25 mm,which improves the measurement speed and reflects the safety representativeness of the sample.The determination time of gas content reduced from 36 to 3 h/piece.Moreover,the absolute error is 0.15–0.50 m^3/t,and the relative error is within 5%.A new engineering method for determining the coal seam gas content is developed according to the above research. | Yanwei Liu Yang Du Zhiqiang Li Fajun Zhao Weiqin Zuo Jianping Wei Hani Mitri | 2020 | International Journal of Mining Science and Technology2020，30，6： | 6 |
| 5 | Voussoir beam model for lower strong roof strata movement in longwall mining - Case study显示文摘The paper presents the influence of varying immediate roof thickness on the lower strong roof strata movement and failure pattern in longwall coal mining with large mining height. The investigation is based on 58 geological drill holes and hydraulic shield pressure measurements around the longwall Panel 42105 of the Buertai Mine in Inner Mongolia Autonomous Region, China. The longwall Panel 42105 is characterized by relatively soft immediate roof strata of varying thickness superposed by strong strata,herein defined as lower strong roof. A voussoir beam model is adopted to interpret the structural movement of the lower strong roof strata and shield pressure measurements. It is shown that when the immediate roof is relatively thick, the broken overlying lower strong roof tends to form a stable voussoir beam with previously broken layer, thus not exerting high pressure on the hydraulic shield and working face. When the immediate roof is relatively thin, the broken overlying lower strong roof tends to behave as a cantilever beam, thus exerting higher pressure on the hydraulic shield and working face. Comparison of model predictions with measured time-weighted average shield pressure(TWAP) shows good agreement. | Chuang Liu Huamin Li Hani Mitri Dongjie Jiang Huigui Li Junfa Feng | 2017 | Journal of Rock Mechanics and Geotechnical Engineering2017，9，6： | 5 |
| 6 | Interaction mechanism of the interface between a deep buried sand and a paleo-weathered rock mass using a high normal stress direct shear apparatus显示文摘In order to evaluate the feasibility of safe mining close to the contact zone under reduced security coal pillar conditions at a coal mine in eastern China, the interaction mechanism of the interface between deep buried sand and a paleo-weathered rock mass was investigated in the laboratory by direct shear testing. A DRS-1 high pressure soil shear testing machine and orthogonal design method were used in the direct shear tests. Variance and range methods were applied to analyze the sensitivity of each factor that has an influence on the mechanical characters of the interface. The test results show that the normal pressure is the main influencing factor for mechanical characteristics of the interface, while the lithological characters and roughness are minor factors; the shear stress against shear displacement curve for the interface shows an overall hyperbola relationship, no obvious peak stress and dilatancy was observed.When the normal pressure is 6 MPa, the shear strengths of interfaces with different roughness are basically the same, and when the normal pressure is more than 8 MPa, the larger the roughness of the interface, the larger will be the shear strength; the shear strength has a better linear relationship with the normal pressure, which can be described by a linear Mohr–Coulomb criterion. | Bai Hanying Li Wenping Ding Qingfeng Wang Qiqing Yang Dongdong | 2015 | International Journal of Mining Science and Technology2015，25，4： | 4 |
| 7 | TLR4 inactivation protects from graft-versus-host disease after allogeneic hematopoietic stem cell transplantation显示文摘Graft-versus-host 疾病(GVHD ) 是在造血的干细胞移植以后的最普通的复杂并发症。澄清像使用费的受体的角色 4 (TLR4 ) ,它是为细菌的 lipopolysaccharides (LPS ) 的主要受体在尖锐 GVHD 的发展,我们使用了一个 TLR4 大美人(TLR4 −/−) 老鼠 GVHD 模型并且分析了内在的免疫学的机制。当 TLR4 −/− 老鼠被用作骨头髓和 splenocyte 房间接枝施主或接受者时, GVHD 症状出现和死亡被推迟与相比野类型(TLR4 +/+) 老鼠。另外,组织病理学说的分析在 TLR4 −/− BALB/c 怪物,肝和小肠织物损坏与最小的淋巴球的渗入被减少。与 TLR4 +/+, TLR4 −/− 老鼠相对照,树枝状的房间没在处于一个不成熟的状态感应、留下的 LPS 期间表示 CD80, CD86, CD40, MHC-II 或 IL-12。而且, TLR4 −/− 鼠标怒气的能力支持 allogeneic T 房间增长的树枝状的房间和,特别地 T 助手房间 1 (Th1 ) 开发显然与 TLR4 +/+ 鼠标相比被稀释 interferon-γ 的树枝状的房间,和层次;(IFN-γ) 并且 IL-10, Th2 房间特定的 cytokines,在 TLR4 −/− BALB/c 比在 TLR4 +/+ BALB/c 妄想的老鼠。总的来说,我们的数据表明 TLR4 可以在 GVHD 和基因治疗可能提供的那指向的 TLR4 的致病起一个作用减少 GVHD 的风险的一条新处理途径。 | Yi Zhao Qiuyan Liu Li Yang Donghua He Lijuan Wang Jun Tian Yi Li Fuming Zi Hanying Bao Yang Yang Yuanyuan Zheng Jimin Shi Xingkui Xue Zhen Cai | 2013 | Cellular & Molecular Immunology2013，10，2： | 4 |
| 8 | Functions and clinical significance of mechanical tumor microenvironment:cancer cell sensing,mechanobiology and metastasis显示文摘Dynamic and heterogeneous interaction between tumor cells and the surrounding microenvironment fuels the occurrence,progression,invasion,and metastasis of solid tumors.In this process,the tumormicroenvironment(TME)fractures cellular and matrix architecture normality through biochemical and mechanical means,abetting tumorigenesis and treatment resistance.Tumor cells sense and respond to the strength,direction,and duration of mechanical cues in the TME by various mechanotransduction pathways.However,far less understood is the comprehensive perspective of the functions and mechanisms of mechanotransduction.Due to the great therapeutic difficulties brought by the mechanical changes in the TME,emerging studies have focused on targeting the adverse mechanical factors in the TME to attenuate disease rather than conventionally targeting tumor cells themselves,which has been proven to be a potential therapeutic approach.In this review,we discussed the origins and roles ofmechanical factors in the TME,cell sensing,mechano-biological coupling and signal transduction,in vitro construction of the tumormechanicalmicroenvironment,applications and clinical significance in the TME. | Hanying Zhou Meng Wang Yixi Zhang Qingqing Su Zhengxin Xie Xiangyan Chen Ran Yan Ping Li Tingting Li Xiang Qin Hong Yang ChunhuiWu Fengming You Shun Li Yiyao Liu | 2022 | Cancer Communications2022，42，5： | 3 |
| 9 | Stabilized cobalt-free lithium-rich cathode materials with an artificial lithium fluoride coating显示文摘Iron-substituted cobalt-free lithium-rich manganese-based materials,with advantages of high specific capacity,high safety,and low cost,have been considered as the potential cathodes for lithium ion batteries.However,challenges,such as poor cycle stability and fast voltage fade during cycling under high potential,hinder these materials from commercialization.Here,we developed a method to directly coat LiF on the particle surface of Li_(1.2)Ni_(0.15)Fe_(0.1)Mn_(0.55O2).A uniform and flat film was successfully formed with a thickness about 3 nm,which can effect-ively protect the cathode material from irreversible phase transition during the deintercalation of Li^(+).After surface coating with 0.5wt%LiF,the cycling stability of Li_(1.2)Ni_(0.15)Fe_(0.1)Mn_(0.55O2) cycled at high potential was significantly improved and the voltage fade was largely suppressed. | Wei Liu Jinxing Li Hanying Xu Jie Li Xinping Qiu | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，5： | 3 |
| 10 | Functional delivery vehicle of organic nanoparticles in inorganic crystals显示文摘Encapsulation of bioactive substances for extended shelf life and controlled,targeted release is critical for their applications in food and drug delivery.Here,a new method has been developed to encapsulate bioactive molecules in the crystal composites,showing greatly enhanced stability and unique pHtriggered response.Chlorophyll,a model bioactive,is first loaded in shellac nanoparticles via coprecipitation with a high encapsulation efficiency,and then the chlorophyll-loaded nanoparticles are incorporated into calcite crystals grown from a gel media containing the nanoparticles.Under the protection of shellac nanoparticles and calcite crystals,chlorophyll shows excellent stability even under light.Encapsulated chlorophyll could only be released by first dissolving the calcite crystals under acidic condition and then dissolving the shellac nanoparticles under alkaline condition.The unique pHtriggered release mimics the pH change from acidic in the stomach to alkaline in the intestine and is thus well suited for controlled,targeted intestinal release.This work suggests that the crystal composites are an ideal delivery vehicle for the functional design of bioactive molecules. | Linlin Kong Xinyi Jin Dapeng Hu Leyun Feng Dong Chen Hanying Li | 2019 | Chinese Chemical Letters2019，30，12： | 2 |
| 11 | Seroprevalence of Toxoplasma gondii infection in arthritis patients in eastern China显示文摘Background:There is accumulating evidence for an increased susceptibility to infection in patients with arthritis.We sought to understand the epidemiology of Toxoplasma gondii infection in arthritis patients in eastern China,given the paucity of data on the magnitude of T.gondii infection in these patients.Methods:Seroprevalence of T.gondii infection was assessed by enzyme-linked immunosorbent assay using a crude antigen of the parasite in 820 arthritic patients,and an equal number of healthy controls,from Qingdao and Weihai cities,eastern China.Sociodemographic,clinical and lifestyle information on the study participants were also obtained.Results:The prevalence of anti-T.gondii IgG was significantly higher in arthritic patients(18.8%)compared with 12%in healthy controls(P<0.001).Twelve patients with arthritis had anti-T.gondii IgM antibodies-comparable with 10 control patients(1.5%vs 1.2%).Demographic factors did not significantly influence these seroprevalence frequencies.The highest T.gondii infection seropositivity rate was detected in patients with rheumatoid arthritis(24.8%),followed by reactive arthritis(23.8%),osteoarthritis(19%),infectious arthritis(18.4%)and gouty arthritis(14.8%).Seroprevalence rates of rheumatoid arthritis and reactive arthritis were significantly higher when compared with controls(P<0.001 and P=0.002,respectively).A significant association was detected between T.gondii infection and cats being present in the home in arthritic patients(odds ratio[OR],1.68;95%confidence interval[CI]:1.24-2.28;P=0.001).Conclusions:These findings are consistent with and extend previous results,providing further evidence to support a link between contact with cats and an increased risk of T.gondii infection.Our study is also the first to confirm an association between T.gondii infection and arthritis patients in China.Implications for better prevention and control of T.gondii infection in arthritis patients are discussed.Trial registration:This is an epidemiological survey,therefore trial registration was not required. | Ai-Ling Tian Yuan-Lin Gu Na Zhou Wei Cong Guang-Xing Li Hany M.Elsheikha Xing-Quan Zhu | 2017 | Infectious Diseases of Poverty2017，6，1： | 2 |
| 12 | SYNTHESIS AND CHARACTERIZATION OF HYDROXYLATED FULLERENE EPOXIDE—AN INTERMEDIATE FOR FORMING FULLEROL显示文摘Fulerol,apolyhydroxylatedfulerenederivative,whichishighlysolubleinwaterbecauseitcontainspolarizedhydroxylgroups,haspotential... | Tianbao Li Xinhai Li Kexiong Huang Hanying Jiang Jing Li | 1999 | Journal of Central South University1999，11，1： | 2 |
| 13 | THERMAL DECOMPOSITION OF ZINC CARBONATE HYDROXIDE HYDRATE POWDERS OF DIFFERENT PARTICLE SIZE AND SAMPLE MASS显示文摘THERMALDECOMPOSITIONOFZINCCARBONATEHYDROXIDEHYDRATEPOWDERSOFDIFFERENTPARTICLESIZEANDSAMPLEMASS①ChenJianxun,ZhaoRuirongandJian... | Chen Jianxun, Zhao Ruirong and Jiang HanyingInstitute of Metallurgy Physical Chemistry and New Chemical Materials,Central South University of Technology, Changsha 410083, P. R. ChinaLi Yanhong, Bao GailingInstitute of Chemistry and Chemical Eng | 1998 | 中国有色金属学会会刊:英文版1998，8，1： | 2 |
| 14 | Linezolid reduces length of stay and duration of intravenous treatment compared with vancomycin for complicated skin and soft tissue infections due to suspected or proven methicillin-resistant Staphylococcus aureus (MRSA) 显示文摘 | hani KM Weigeh J Li JZ | 2005 | Int J Antimicrob Agents2005，26，： | 1 |
| 15 | The oxidation of NdFeB magnets显示文摘 | LI Y EVANS H E HANIS I R | 2003 | Oxidation of Metals2003，59，： | 1 |
| 16 | GRHL 2 deficiency impairs otic development and hearing ability in a zebrafish model of the progressive dominant hearing loss DFNA28显示文摘 | HanY Mu Y Li X Xu P Tong J Liu Z | 2011 | Hum Mol Genet2011，20，： | 1 |
| 17 | Modal cutoff in rare-earth-doped photonic crystal fibers with multi-layer air-holes missing in the core显示文摘The various mode effective indices of the doped photonic crystal fibers (PCFs) are compared, the mode field distributions of the fundamental mode and the second-order mode are analyzed, and the single-mode condition is presented. The mode effective indices of large-core doped PCFs with different core indices and structure parameters are simulated by the finite element method (FEM). The relations of the core index with the fiber structure parameters of pitch, hole-to-pitch ratio and core diameter are obtained for single-mode propagation. In the design and fabrication of the doped PCF, we can adjust the core index and fiber structure parameters to achieve large mode area and single-mode propagation. | ZHAO Xing-tao ZHENG Yi LIU Xiao-xu LI Shu-guang HANYing HOU Zhi-yun WANG Na HOU Lan-tian | 2013 | Optoelectronics Letters2013，9，3： | 1 |
| 18 | Crystal Growth and Characterization of Fluorinated Perylene Diimides显示文摘 | HUANG Jiachi LI Hanying MO Xiong SHI Minmin WANG Mang CHEN Hongzheng | 2014 | Chemical Research in Chinese Universities2014，30，1： | 1 |
| 19 | Detection of HIV-1 viruses in tears of patients even under long-term HAART 显示文摘 | HanY WuN ZhuW LiY ZuoL YeJ QiuZ XieJ Li T | 2011 | AIDS2011，25，15： | 1 |
| 20 | The limit law of the iterated logarithm in Banach space显示文摘 | LI Deli LIANG Hanying | 2013 | Statistics and Probability Letters2013，83，： | 1 |
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