3篇
您的检索式：作者名="Hao Xiqing"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Measurement 3f Cosmic Ray Flux in China JinPing underground Labora- Lory显示文摘 | Wu Yueheng Hao Xiqing Yue Qian | 2013 | Chinese Physics C2013，37，08： | 1 |
| 2 | Onset location of scintillation-producing spread-F plume over Sanya显示文摘Equatorial spread-F (ESF) backscatter plumes are often observed in radar range-time-intensity (RTI) maps at low latitude. Except case studies, few statistical investigations on the onset locations of scintillation-producing ESF plumes at given sites have been conducted. In this study, a statistical analysis is carried out on onset locations of ESF backscatter plumes observed at a low-latitude location Sanya (18.4°N, 109.6°E; dip lat 12.8°N) during equinoctial months of 2013. By employing a tracing method to locate backscatter plumes, we estimate the onset longitudes of periodic plumes obtained from the Sanya VHF radar five-beam steering measurements. The results show that the inter-plume distances (in longitude) are mostly confined within 200–600 km, and the ESF plumes producing ionospheric scintillations over Sanya are almost exclusively generated at the longitudes of 94°–110°E. The results indicate the necessity to monitor ESF plume initial generation in the longitude region of 94°–110°E to better understand the day-to-day variability in the occurrence of ionospheric scintillations over Sanya. | ZHENG JianChang HUANG ZhaoGuo WU Zhi HAO XiQing JI JiaLun NING BaiQi HU LianHuan ZHAO XiuKuan LI GuoZhu | 2016 | Science China Earth Sciences2016，59，8： | 0 |
| 3 | Near-infrared light(NIR)-responsive nanoliposomes combining photodynamic therapy and chemotherapy for breast tumor control显示文摘Light-responsive carriers have been used for the controlled release of antitumor drugs in recent years.However, most light-responsive vectors require high-energy ultraviolet or visible light to achieve local drug release, and ultraviolet light would cause cellular damage. Near-infrared light has a deeper tissuepenetration depths and minimal harm to tissues, but it is difficult to cleave the chemical bond directly.The aim of this study is to develop a novel near-infrared light-responsive carrier for local release of antitumor drugs. Unsaturated phospholipids can be oxidized by singlet oxygen to achieve liposomal drug release, and singlet oxygen can be produced by photosensitizer under light irradiation. A new near-infrared light-responsive nanoliposome was designed that imparts light-triggered local drug release. Nanoliposomes, which were composed of matrix phospholipids and unsaturated phospholipids, were prepared by ammonium sulfate gradient method, and loaded with antitumor drug doxorubicin(DOX) and photosensitizer 1,4,8,11,15,18,22,25-octabutoxypalladium phthalocyanine. Under near-infrared light, photosensitizers could produce singlet oxygen and damage tumor cells by photodynamic therapy. Simultaneously, the unsaturated phospholipids were oxidized by singlet oxygen and result in DOX release, causing sustained cell damage by chemotherapy. Near-infrared light-responsive nanoliposomes exhibit enhanced anticancer activity owing to combined treatment of photodynamic therapy and chemotherapy. A new platform is thus offered for designing effective intracellular drug-release systems, holding great promise for future cancer therapy. | Guangzhao Lu Xiqing Gao He Zhang Yeye Zhang Yuan Yu Zhiguo Sun Wei Li Wei Wu Ying Lu Hao Zou | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员