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2篇 您的检索式:作者名="Haolong Zeng"
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1Comparison of CS,CGM and CS-CGM for Prediction of Pipe’s Inner Surface in FGMs显示文摘The cuckoo search algorithm(CS)is improved by using the conjugate gradient method(CGM),and the CS-CGM is proposed.The unknown inner boundary shapes are generated randomly and evolved by Lévy flights and elimination mechanism in the CS and CS-CGM.The CS,CGM and CS-CGM are examined for the prediction of a pipe’s inner surface.The direct problem is two-dimensional transient heat conduction in functionally graded materials(FGMs).Firstly,the radial integration boundary element method(RIBEM)is applied to solve the direct problem.Then the three methods are compared to identify the pipe’s inner surface with the information of measured temperatures.Finally,the influences of timepoints,measurement point number and random noise on the inverse results are investigated.It is found that the three algorithms are promising and can be used to identify the pipe’s inner surface.The CS-CGM has higher accuracy and faster convergence speed than the CS and CGM.The CS and CS-CGM are insensitive to the initial values.The CGM and CS-CGM are more insensitive to the measurement noises compared with the CS.With the increase of timepoints and measurement points,and with the decrease of measurement noises,the inverse results are more accurate.Haolong Chen Bo Yu Huanlin Zhou Zeng Meng 2017Computers, Materials & Continua2017,,4:1
2Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients显示文摘Antibody-dependent cellular cytotoxicity(ADCC)responses to viral infection are a form of antibody regulated immune responses mediated through the Fc fragment.Whether severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)triggered ADCC responses contributes to COVID-19 disease development is currently not well understood.To understand the potential correlation between ADCC responses and COVID-19 disease development,we analyzed the ADCC activity and neutralizing antibody response in 255 individuals ranging from asymptomatic to fatal infections over 1 year post disease.ADCC was elicited by 10 days post-infection,peaked by 11-20 days,and remained detectable until 400 days post-infection.In general,patients with severe disease had higher ADCC activities.Notably,patients who had severe disease and recovered had higher ADCC activities than patients who had severe disease and deceased.Importantly,ADCC activities were mediated by a diversity of epitopes in SARS-COV-2-infected mice and induced to comparable levels against SARS-CoV-2 variants of concern(VOCs)(B.1.1.7,B.1.351,and P.1)as that against the D614G mutant in human patients and vaccinated mice.Our study indicates anti-SARS-CoV-2 ADCC as a major trait of COVID-19 patients with various conditions,which can be applied to estimate the extra-neutralization level against COVID-19,especially lethal COVID-19.Yuanling Yu Meiyu Wang Xiaoai Zhang Shufen Li Qingbin Lu Haolong Zeng Hongyan Hou Hao Li Mengyi Zhang Fei Jiang Jiajing Wu Ruxia Ding Zehua Zhou Min Liu Weixue Si Tao Zhu Hangwen Li Jie Ma Yuanyuan Gu Guangbiao She Xiaokun Li Yulan Zhang Ke Peng Weijin Huang Wei Liu Youchun Wang 2021Signal Transduction and Targeted Therapy2021,6,10:0
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