|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MicroRNA regulation of innate immune responses in epithelial cells显示文摘Mucosal surface epithelial cells are equipped with several defense mechanisms that guard against pathogens.Recent studies indicate that microRNAs(miRNAs)mediate post-transcriptional gene suppression and may be a critical component of the complex regulatory networks in epithelial immune responses.Transcription of miRNA genes in epithelial cells can be elaborately controlled through pathogen recognition receptors,such as Toll-like receptors(TLRs),and associated nuclear factor kappaB(NF-kB)and mitogen-activated protein kinase(MAPK)pathways,and ultimately nuclear transcription factor associated-transactivation and transrepression.Activation of these intracellular signaling pathways may also modulate the process of miRNA maturation.Functionally,miRNAs may modulate epithelial immune responses at every step of the innate immune network,including production and release of cytokines/chemokines,expression of adhesion and costimulatory molecules,shuttling of miRNAs through release of exosomes and feedback regulation of immune homeostasis.Therefore,miRNAs act as critical regulators to the fine-tuning of epithelial immune responses. | Rui Zhou Steven P O’Hara Xian-Ming Chen | 2011 | Cellular & Molecular Immunology2011，8，5： | 13 |
| 2 | 尿酸是正常高值血压发展为高血压的一个重要危险标志物显示文摘正常高值血压常发展为高血压,是一个与心血管病和脑卒中高死亡率和高发病率相关的事件。然而,正常高值血压发展成高血压的危险因素仍不清楚。研究者采用年龄(52.1±11.0)岁日本成年高血压患者3584例(2081例为男性)的资料进行前瞻性群体研究,研究对象在2004年被发现处于正常高值血压阶段,并在2009年重新进行检查。 | 黄洁 叶鹏 Kuwabara M Hisatome I Niwa K Hara S Roncal-Jimenez CA Bjornstad P Nakagawa T Andres-Hernando A Sato Y Jensen T Garcia G Rodriguez-Iturbe B Ohno M Lanaspa MA Johnson RJ | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 3 | Treatment of ovariectomized rats with strontium ranelate improves bon etrength and bon equality显示文摘 | BAIN S SHEN V HARA P | 2004 | Calcif Tissue Int2004，74，： | 1 |
| 4 | Genetic variation in the gene encod- ing adiponectin is associated with an increased risk of type 2 diabe- tes in the Japanese population 显示文摘 | Hara K Boutin P Mori Y | 2002 | Diabetes2002，51，2： | 1 |
| 5 | Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome显示文摘 | Ehrmann D A Schwarz P E Hara M | 2002 | J Clin Endocrinol Metab2002，87，4： | 1 |
| 6 | Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after MCA occlusion显示文摘 | HARA H HUANG P L PANAHIAN N | 1996 | Cereb Blood Flow Metab1996，16，4： | 1 |
| 7 | Genetic variation in the gene encoding adiponectin is associated with an increased risk of type2 diabetes in the Japanese population显示文摘 | Hara K Boutin P Moil Y et a1 | 2002 | Diabetes2002，51，2： | 1 |
| 8 | Consolidated rockfill design and quality control at Kidd Greek Mine显示文摘 | FARSANGI P HARA A | 1993 | CIM Bulletin1993，973，： | 1 |
| 9 | A peer-led AIDS prevention program for students in an alternative school显示文摘 | | 1996 | Journal of School Health1996，66，： | 1 |
| 10 | Sol-gels and cross-linkedaggregates of lipase PS from Burkholderia cepacia and theirapplication in dry organic solvents显示文摘 | Hara P Hanefeld U Kanerva L T | 2008 | Journal of MolecularCatalysis B:Enzymatic2008，50，234： | 1 |
| 11 | Photosynthetic recovery of foliage after wind disturbance activates ecosystem CO2 uptake in cool temperate forests of northern Japan显示文摘 | Toda M Kolari P Nakai T Kodama Y Shibata H Yoshida T Uemura S Sumida A Kato K Ono K Hara T | | 0，，： | 1 |
| 12 | Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population显示文摘 | HARA K BOUTIN P MORI Y | 2002 | Diab2002，51，2： | 1 |
| 13 | Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism显示文摘 | HARA K YONEZAWA K WENG Q P | 1998 | Journal of Biological Chemistry1998，273，14： | 1 |
| 14 | Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius显示文摘 | O HARA A M O REGAN P FANNING A | 2006 | Immunology2006，118，2： | 1 |
| 15 | Effect of Temperature During Ripening on Grain Quality of Rice显示文摘 | RESURRECCION A P HARA T | 1977 | Soil Sci Plant Nutr1977，23，1： | 1 |
| 16 | Characterization of a cDNA coding for human factor Ⅶ显示文摘 | Hagen FS Gray CL 0'Hara P | 1986 | Proc Natl Acad Sci USA1986，83，8： | 1 |
| 17 | Wolbachia-induced incompatibility precedes other hybrid incompatibilities in Nasonia显示文摘 | Bordenstein S R O'Hara F P Werren J H | 2001 | Nature2001，409，6821： | 1 |
| 18 | Suppression of mammary ep- ithelial cell differentiation by the helix-loop-helix protein Id-1显示文摘 | Desprez P Y Hara E Bissell M J | 1995 | Mol Cell Bio1995，15，6： | 1 |
| 19 | Measuring trade show effectiveness: An effective exercise? 显示文摘 | Herbig P Hara B O Palumbo F | 1994 | Industrial Marketing Management1994，23，2： | 1 |
| 20 | Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population显示文摘 | Hara K Boutin P Mori Y | 2002 | Diabetes2002，51，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员