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66篇 您的检索式:作者名="Hardt R"
    题名 作者 年代 出处 被引量
1A five body--Three dimensional dynamic analysis of walking 显示文摘Hardt D E Mann R W 1980Journal of Biomechanics1980,13,5:1
2Understanding time course of DLK can help eliminate visual loss 显示文摘Eric J Linebarger David R Hardte Y Ralph Chu 1999J Oeul Surg News1999,10,:1
3Neomarinone and new cytotoxic marinone derivatives, produced by a marine filamentous bacterium (Actinomycetales) 显示文摘Ingo H Hardt Paul R Jensen William Fenical 2000Tetrahedron Lett2000,41,13:1
4Mappings minimizing the LP norm of the gradient显示文摘Hardt R Lin F H 1987Communications on Pure and Applied Mathematics1987,40,:1
5SARA: A cognitive process model to simulate the anchoring effect and hindsight bias 显示文摘Pohl R F Eisenhauer M Hardt O 2003Memory2003,11,45:1
6Harmonic extensions of quasiconformal maps to hyperbolic space显示文摘HARDT R WOLF M 1997Indiana Univ Math1997,46,:1
7Sheet metal die forming using closed-loop shape control显示文摘Hardt D E Webb R D 1982Annals of CIRP1982,31,2:1
8A transfer function description of sheet metal forming for process control显示文摘Webb R D Hardt D E 1991Journal of Engineering for Industry Transaction ASME1991,33,2:1
9Neomarinone, and New cytotoxic marine derivatives produced by a marine filamentous bacterium (Actinomycetales)显示文摘Hardt I H Jensen P R Finical W 2000Tetrahedron Lett2000,41,13:1
10On the spectrum of unbounded off-diagonal 2 × 2 operator matrices in Banach 显示文摘Hardt V Mennicken R 2001opera tor Theery :Advances and Applications2001,124,:1
11ATransfer function description of sheet metal forming for process control显示文摘Webb R D Hardt D E 0,,02:1
12On the spectrum of the product of closed operators 显示文摘Hardt V Konstantinov A and Mennicken R 2000Math Nachr2000,,215:1
13人乳头瘤病毒16/18型AS04佐剂疫苗预防肿瘤基因型HPV引起的宫颈感染和癌前病变的效应(PATRICIA):一项在年轻女性中进行的双盲、随机研究的最终分析显示文摘背景在年轻成人中进行的Ⅲ期随机、双盲对照PATRICIA试验(PApilloma TRial)的事件驱动期中分析显示,人乳头瘤病毒(HPV)16/18AS04佐剂疫苗具有免疫原性,且总体耐受性良好,对HPV16或HPV18感染及相关的癌前病变具有预防效应。本文作者旨在评估最终事件驱动分析中的疫苗效应。方法将在基线、1个月和6个月接种疫苗的15~25岁女性分类为符合方案的效应队列(ATP-E队列;疫苗组8093例,对照组8069例)、总接种队列(TVC;包括至少接种1剂疫苗的所有女性,而不考虑其基线HPV状态;代表普遍的年轻女性人群,包括性活跃者;疫苗组9319例,对照组9325例)和TVC-naive(无证据表明基线时存在肿瘤基因型HPV感染;代表无性行为女性;疫苗组5822例,对照组5819例)。主要终点是。在基线时血清和DNA均为阴性且在6个月时为相应类型(ATP-E队列)的女性中,评估疫苗对HPV16或HPV18相关性宫颈上皮内瘤变≥2级(CIN2+)的预防效应。该试验在ClinicalTrial.gov上的注册编码为NCT00122681.结果第3剂疫苗接种后平均随访34.9个月(s=6.4)。在主要分析中疫苗对HPV16/18相关性CIN2+的预防效应为92.9%(96.1%CI79.9%~98.3%),在对可能因多种肿瘤基因型HPV引起的病变(ATP-E队列)的分析中,其预防效应为98.1%(96.1%CI88.4%~100%)。不考虑病变HPVDNA时,疫苗对CIN2+的预防效应在TVC中为30.4%(96.1%CI16.4%~42.1%),在TVC-naive中为70.2%(96.1%CI54.7%~80.9%);而对CIN3+的相应效应在TVC中为33.4%(96.1%CI9.1%~51.5%).在TVC-naive中为87.0%(96.1%CI54.9%~97.7%).在预防12种非疫苗肿瘤基因型HPv相关性CIN2+的效应为54.0%(96.1%CI34.0%~68.4%:ATP-E队列)。在TVC中可见对HPV31、33和45相关性CIN2+的个体交叉保护效应。结论HPV16/18 AS04佐剂疫苗表现出对HPV16/18和非疫苗肿瘤基因型HPV相关性CIN2+较强的预防效应,而要获得整体预防效应就需要在更广泛的人群中进行大面积强化免疫计划。基金 葛兰素史克。J Paavonen P Naud J Salmeron C M Wheeler S-N Chow D Apter H Kitchener X Castellsague J C Teixeira S R Skinner J Hedrick U Jaisamrarn G Limson S Garland A Szarewski B Romanowski F Y Aoki T F Schwarz W A J Poppe F X Bosch D Jenkins K Hardt T Zahaf D Descamps F Struyf M Lehtinen G Dubin 周彩虹(译) 2009世界临床医学2009,,12:1
14A transfer function de- scription of sheet metal forming for process control 显示文摘WEBB R D HARDT D E 1991Journal of Engineering for Industry1991,113,:1
15Existence and partial regularity of static liquid crystal configurations显示文摘HARDT R KINDERLEHRER D LIN F H 1986Comm Math Phys1986,105,:1
16Stable defects of minimizers of constrained variational principles 显示文摘HARDT R KINDERLEHRER D LIN F H 1988Ann Inst H Poincare Anal Nonlineaire1988,5,:1
17Partially constrained boundary con- ditions with energy minimizing mappings 显示文摘HARDT R LIN F H 1989Comm Pure Appl Math1989,42,:1
18Ultrasound exposure can increase the membrane permeability of human neutrophil granulocytes containing microbubbles without causing complete cell destruction显示文摘Korosoglou G Hardt S E Bekeredjian R 2006Ultrasound Med Biol2006,32,2:1
19Mappings minimizing the L^p norm of the gradient显示文摘Hardt R Lin F H 1987Comm Pure Appl Math1987,40,:1
20A Transfer Function Description of Sheet Metal Forming for Process Control 显示文摘R D Webb David E Hardt 1991Journal of Engineering for Industry1991,,:1
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