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| 1 | Epithelial ovarian cancer:An overview显示文摘Ovarian cancer is the second most common gyneco-logical cancer and the leading cause of death in the United States. In this article we review the diagnosis and current management of epithelial ovarian cancer which accounts for over 95 percent of the ovarian malignancies. We will present various theories about the potential origin of ovarian malignancies. We will discuss the genetic anomalies and syndromes that may cause ovarian cancers with emphasis on Breast cancer type 1/2 mutations. The pathology and pathogenesis of ovarian carcinoma will also be presented. Lastly, we provide a comprehensive overview of treatment strategies and staging of ovarian cancer, conclusions and future directions. | Arpita Desai Jingyao Xu Kartik Aysola Yunlong Qin Chika Okoli Ravipati Hariprasad Ugorji Chinemerem Candace Gates Avinash Reddy Omar Danner Geary Franklin Anachebe Ngozi Guilherme Cantuaria Karan Singh William Grizzle Charles Landen Edward E Partridge Valerie Montgomery Rice E Shyam P Reddy Veena N Rao | 2014 | World Journal of Translational Medicine2014，3，1： | 10 |
| 2 | Interface Engineering of NixSy@MnOxHy Nanorods to Efficiently Enhance Overall-Water-Splitting Activity and Stability显示文摘Exploring highly active and stable transition metal-based bifunctional electrocatalysts has recently attracted extensive research interests for achieving high inherent activity, abundant exposed active sites, rapid mass transfer, and strong structure stability for overall water splitting. Herein, an interface engineering coupled with shell-protection strategy was applied to construct three-dimensional(3D) core-shell NixSy@MnOxHy heterostructure nanorods grown on nickel foam(NixSy@MnOxHy/NF) as a bifunctional electrocatalyst. NixSy@MnOxHy/NF was synthesized via a facile hydrothermal reaction followed by an electrodeposition process. The X-ray absorption fine structure spectra reveal that abundant Mn-S bonds connect the heterostructure interfaces of N ixSy@MnOxHy, leading to a strong electronic interaction, which improves the intrinsic activities of hydrogen evolution reaction and oxygen evolution reaction(OER). Besides, as an efficient protective shell, the MnOxHy dramatically inhibits the electrochemical corrosion of the electrocatalyst at high current densities, which remarkably enhances the stability at high potentials. Furthermore, the 3D nanorod structure not only exposes enriched active sites, but also accelerates the electrolyte diffusion and bubble desorption. Therefore, NixSy@MnOxHy/NF exhibits exceptional bifunctional activity and stability for overall water splitting, with low overpotentials of 326 and 356 mV for OER at 100 and 500 mA cm^(–2), respectively, along with high stability of 150 h at 100 mA cm^(–2). Furthermore, for overall water splitting, it presents a low cell voltage of 1.529 V at 10 mA cm^(–2), accompanied by excellent stability at 100 mA cm^(–2) for 100 h. This work sheds a light on exploring highly active and stable bifunctional electrocatalysts by the interface engineering coupled with shell-protection strategy. | Pan Wang Yuanzhi Luo Gaixia Zhang Zhangsen Chen Hariprasad Ranganathan Shuhui Sun Zhicong Shi | 2022 | Nano-Micro Letters2022，14，7： | 4 |
| 3 | Sensory-motor responses to mechanical stimulation of the esophagus after sensitization with acid显示文摘AIM: Sensitization most likely plays an important role in chronic pain disorders, and such sensitization can be mimicked by experimental acid perfusion of the esophagus.The current study systematically investigated the sensory and motor responses of the esophagus to controlled mechanical stimuli before and after sensitization.METHODS: Thirty healthy subjects were included.Distension of the distal esophagus with a balloon was performed before and after perfusion with 0.1 mol/L hydrochloric acid for 30 min. An impedance planimetry system was used to measure cross-sectional area,volume, pressure, and tension during the distensions. A new model allowed evaluation of the phasic contractions by the tension during contractions as a function of the initial muscle length before the contraction (comparable to the Frank-Starling law for the heart). Length-tension diagrams were used to evaluate the muscle tone before and after relaxation of the smooth muscle with butylscopolamine.RESULTS: The sensitization resulted in allodynia and hyperalgesia to the distension volumes, and the degree of sensitization was related to the infused volume of acid. Furthermore, a nearly 50% increase in the evoked referred pain was seen after sensitization. The mechanical analysis demonstrated hyper-reactivity of the esophagus following acid perfusion, with an increased number and force of the phasic contractions, but the muscle tone did not change.CONCLUSION: Acid perfusion of the esophagus sensitizes the sensory pathways and facilitates secondary contractions.The new model can be used to study abnormal sensorymotor mechanisms in visceral organs. | Asbjφrn Mohr Drewes Hariprasad Reddy Camilla Staahl Jan Pedersen Peter Funch-Jensen Lars Arendt-Nielsen Hans Gregersen | 2005 | World Journal of Gastroenterology2005，11，28： | 3 |
| 4 | Determination of vitreous, aqueous, and plasma concentration of orally administered voriconazole in humans显示文摘 | Hariprasad SM Mieler WF Holz ER | 2004 | Arch Ophthalmol2004，122，1： | 1 |
| 5 | Microstructures and mechanical properties of dispersion-strengthened high-temperature Al-8.5Fe-1.2V-1.7Si alloys produced by atomized melt deposition process显示文摘 | S. Hariprasad S. M. L. Sastry K. L. Jerina R. J. Lederich | 1993 | Metallurgical Transactions A1993，，4： | 1 |
| 6 | Surface roughness parameters optimization in machining A356/SiC/20p metal matrix composites by PCD tool using response surface methodology and desirability function 显示文摘 | K Palanikumar N Muthukrishnan K S Hariprasad | 2008 | Machining Science and Technology2008，12，： | 1 |
| 7 | 查看详情显示文摘 | Hariprasad E Radhakrishnan T P | | 0，，： | 1 |
| 8 | Mechanism of aflatoxin uptake in roots of intact groundnut ( Arachis hypogaea L.) seedlings显示文摘 | M. Snigdha P. Hariprasad G. Venkateswaran | 2013 | Environmental Science and Pollution Research2013，，12： | 1 |
| 9 | Determination of vitreous,aqueous,and plasma concentration of orally administered voriconazole in humans显示文摘 | Hariprasad SM Mieler WF Holz ER | 2004 | Arch Ophthalmol2004，122，1： | 1 |
| 10 | Management of endogenous fungal endophthalmitis with voriconazole and caspofungin显示文摘 | Breit SM Hariprasad SM Mieler WF | 2005 | Am J Ophthalmol2005，139，1： | 1 |
| 11 | Trivedi Harold Moore A Randomized Prospective Trim to Asse - ss the Role of Saline Hydration on the Development of Contrast Nephrotoxic - ity 显示文摘 | Hariprasad S | 2003 | Nephron Clin Pract2003，93，： | 1 |
| 12 | Determination of vitreous,aqueous,and plasma concentration of orally administered voriconazole in humans显示文摘 | Hariprasad S M Mieler WF Holz ER | 2004 | Arch Ophthalmol2004，122，1： | 1 |
| 13 | Aqueous and vitreous concentrations following topical administration of 1% voriconazole in humans 显示文摘 | Vemulakonda GA Hariprasad SM Mieler WF | 2008 | Arch Ophthalmol2008，126，1： | 1 |
| 14 | Gender Differences in Pain and Biomechanical Responses After Acid Sensitization of the Human Esophagus显示文摘 | Hariprasad Reddy MD Lars Arendt-Nielsen PhD Camilla Staahl MScPharm Jan Pedersen MD PhD Peter Funch-Jensen MD PhD Hans Gregersen MD PhD Asbj?rn Mohr Drewes MD PhD | 2005 | Digestive Diseases and Sciences2005，，11： | 1 |
| 15 | Successful treatment of postoperative fungal endophthalmitis using intravitreal and intracameral voriconazole显示文摘 | Lin RC Sanduja N Hariprasad SM | 2008 | J Ocul Pharmacol Ther2008，24，2： | 1 |
| 16 | Microstructure and Mechanical Properties of Dispersion Strengthened by Atomized Melt Deposition Process显示文摘 | Hariprasad S Sastru S L Jenna K L | 1993 | Metal Trans1993，24，4： | 1 |
| 17 | Differences Between Male and Female Responses to Painful Thermal and Mechanical Stimulation of the Human Esophagus显示文摘 | Jan Pedersen Hariprasad Reddy Peter Funch-Jensen Lars Arendt-Nielsen Hans Gregersen Asbj?rn Mohr Drewes | 2004 | Digestive Diseases and Sciences (-)2004，，7： | 1 |
| 18 | Surface roughness parameters optimization in machining A356/SiC/20p metal matrix composites by PCD tool using response surface methodology and desirability function显示文摘 | Palanikumar K Muthukrishnan N Hariprasad K S | 2008 | Machining Science and Technology2008，12，： | 1 |
| 19 | Vitreous and aqueous penetration of orally administered gatifloxacin in humans 显示文摘 | Hariprasad SM Mieler WF Holz ER | 2003 | Arch Ophthalmol2003，121，3： | 1 |
| 20 | Leaching of manganese ores using sawdust as a reductant显示文摘 | Hariprasad D B D M K | | 0，，02： | 1 |
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