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| 1 | Prevalence of advanced liver fibrosis and steatosis in type-2 diabetics with normal transaminases:A prospective cohort study显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)and type-2 diabetes mellitus(T2DM)have an intricate bidirectional relationship.Individuals with T2DM,not only have a higher prevalence of non-alcoholic steatosis,but also carry a higher risk of progression to nonalcoholic steatohepatitis.Experts still differ in their recommendations of screening for NAFLD among patients with T2DM.AIM To study the prevalence of NAFLD and advanced fibrosis among our patient population with T2DM.METHODS During the study period(November 2018 to January 2020),59 adult patients with T2DM and 26 non-diabetic control group individuals were recruited prospectively.Patients with known significant liver disease and alcohol use were excluded.Demographic data and lab parameters were recorded.Liver elastography was performed in all patients.RESULTS In the study group comprised of patients with T2DM and normal alanine aminotransferase levels(mean 17.8±7 U/L),81%had hepatic steatosis as diagnosed by elastography.Advanced hepatic fibrosis(stage F3 or F4)was present in 12%of patients with T2DM as compared to none in the control group.Patients with T2DM also had higher number of individuals with grade 3 steatosis[45.8%vs 11.5%,(P<0.00001)and metabolic syndrome(84.7%vs 11.5%,P<0.00001)].CONCLUSION A significant number of patients with T2DM,despite having normal transaminase levels,have NAFLD,grade 3 steatosis and advanced hepatic fibrosis as measured by liver elastography. | Jasbir Makker Hassan Tariq Kishore Kumar Madhavi Ravi Danial Haris Shaikh Vivien Leung Umar Hayat Muhammad T Hassan Harish Patel Suresh Nayudu Sridhar Chilimuri | 2021 | World Journal of Gastroenterology2021，27，6： | 2 |
| 2 | Antioxidant activity and hepatoprotective potential of Phyllanthus niruri 显示文摘 | HARISH R SHIVANANDAPPA T | 2006 | Food Chemistry2006，95，2： | 1 |
| 3 | Constructed wetlands as re- circulation filters in large-scale shrimp aquaculture显示文摘 | DAVID R T HARISH B RONALD R | | AquaculturaI En- gineering0，26，： | 1 |
| 4 | Rhizosphere and endophytic bacteria for induction of systemic resistance of banana plantlets against bunchy top virus显示文摘 | Kavino M Harish S Kumar N Saravanakumar D Damodaran T Soorianathasundaram K Samiyappan R | | 0，，05： | 1 |
| 5 | Studies on characteristics of CO2 laser-GTAW hybrid welding of austenitic显示文摘 | RAKESH KAULL HARISH KUMARL RAO B T | 2010 | Journal of Laser Applications2010，2，22： | 1 |
| 6 | Antioxidantactivity of the roots of Decalepis hamiltonii (Wight & Arn)显示文摘 | Srivastava A Harish S R Shivanandppa T | 2006 | LWT-Food Science and Technology2006，39，10： | 1 |
| 7 | Antioxidant activity of the roots of Decalepis hamiltonii (Wight & Am) 显示文摘 | Srivastava A Harish S R Shivananappa T | 2006 | LWT -Food Sci- ence and Technology2006，39，10： | 1 |
| 8 | Constructed wetland as recirculation filters in large-scale shrimp aquaculture 显示文摘 | Harish B Ronald R | 2002 | Aquacultural Engineering2002，26，2： | 1 |
| 9 | Antioxidant activity of the roots of Decalepis hamiltonii (Wight & Am)显示文摘 | SRIVASTAVA A HARISH S R SHIVANANDPPA T | 2006 | LWT- Food Science and Teclmology2006，39，10： | 1 |
| 10 | Antioxidant activity of the roots of Decalepis hamiltonii ( Wight & Am) 显示文摘 | SRIVASTAVA A HARISH S R SHIVANANDAPPA T | 2006 | LWT-Food Science and Technology2006，39，10： | 1 |
| 11 | Symptomatic seizures in neurosyphilis: an experience from a university hospital in south India 显示文摘 | SinhaS Harish T Taly AB | 2008 | Seizure2008，17，8： | 1 |
| 12 | Sythesis and in Vitro Calcium Channel Blocking Activ- ity of Symmetrical and Unsymmetrical Substituted 1,4-Dihy- dropyridine Derivatives 显示文摘 | HARISH KUMAR NAYEEM NAIRA DHARMARAIAN T S | 2009 | Asia Journal of Chemistry2009，21，6： | 1 |
| 13 | Game theoretic model for P2P trust management显示文摘 | Harish M Mahalakshmi G S Geetha T V | 2007 | Proceed- ings-International Conference on Computational Intelligence and Multimedia Applications2007，，12： | 1 |
| 14 | Creep fail- stainless steel joints 显示文摘 | Harish Kumar D Shaktivelu T ures in laser welded 316L (N) Nanda Gopal M | 2013 | Journal of Materials Science Research2013，2，1： | 1 |
| 15 | Flupirtine:Clinical pharmacology显示文摘 | Harish S Bhuvana K Bengalorkar GM Kumar T | | 0，，： | 1 |
| 16 | Symptomatic seizures in neurosyphilis:an experience from a university hospital in south India显示文摘 | Sinha S Harish T Taly A B | 2008 | Seizure2008，17，8： | 1 |
| 17 | Antioxidant activity of the roots of Decalepis hamiltonii (Wight & Arn)显示文摘 | SRIVASTAVA A HARISH S R SHIVANANDAPPA T | 2006 | LWT- Food Science and Technology2006，39，10： | 1 |
| 18 | In-situ measurementof near-surface fretting contact temperatures in an aluminum alloy 显示文摘 | SZLOWINSKI M P HARISH G FARRIS T N | 1999 | ASME J Tribol1999，121，： | 1 |
| 19 | Antioxidant Activity and Hepatoprotective Potential of Phyllanthus niruri显示文摘 | Shivanandappa T | 2006 | Food Chemistry2006，95，2： | 1 |
| 20 | Measurements of particle number and mass concentrations and size distributions in a tunnel environment显示文摘 | MICHAEL D G SATYA B T HARISH P | 2005 | Environ Sci Technol2005，39，： | 1 |
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