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| 1 | Correlation of leaking microaneurysms with retinal thickening in diabetic retinopathy显示文摘AIM: To investigate the contribution of fluorescein angiographic leaking microaneurysms (leak-MA) versus non-leaking microaneurysms (non-leak-MA) to retinal thickening in diabetic retinopathy.METHODS: A consecutive series of 38 eyes from 24 patients with diabetic retinopathy was included.Leak-MA and non-leak-MA in each eye were selected in pairs at corresponding topographic location.Leaking was defined by late phase fluorescein angiograms compared to early phase.Retinal thickness was measured with Heidelberg Spectralis OCT topographically aligned on early phase angiograms at the MA site and within a 1 mm circle.RESULTS: In all eyes,significant retinal thickening at the site of leaking compared to non-leaking microaneurysms was observed (356±69μm vs 318±56μm,P <0.001),showing a mean increase in thickness in the areas of leak-MA vs non-leak-MA of 38±39μm (95% confidence interval 2551μm,P<0.001).All 1mm area measurements also showed significant (P<0.001) thickening of the leak-MA with average thickness of leak-MA vs non-leak-MA as 351±67μmvs 319±59μm;minimum thickness 311±62μm vs 284±60μm;maximum thickness 389±78μm vs 352±66μm;and retina volume 26.4±6.0mmvs 23.6±3.7mm3,respectively.CONCLUSION: Leaking of microaneurysms on fluorescein angiography appears to cause focal thickening of retina,which can be measured with high-resolution OCT.Therefore,targeting leaking microaneursyms in diabetic retinopathy has the potential to reduce retinal thickening. | Lukas Reznicek Marcus Kernt Christos Haritoglou Michael Ulbig Anselm Kampik Aljoscha S Neubauer | 2011 | International Journal of Ophthalmology(English edition)2011，4，3： | 2 |
| 2 | Comparison of Intravitreal Bevacizumab versus Triamcinolone for the Treatment of Diffuse Diabetic Macular Edema显示文摘 | Kreutzer Thomas C Al Saeidi Rashid Kook Daniel Wolf Armin Ulbig Michael W Neubauer Aljoscha S Haritoglou Christos | 2010 | Ophthalmologica2010，，4： | 2 |
| 3 | Ana- tomic success of scleral buckling for rhegmatogenous retinal detach- ment- a retrospective study of 524 cases显示文摘 | HARITOGLOU C BRANDLHUBER U KAMPIK A | 2010 | Ophthalmologica2010，224，5： | 1 |
| 4 | ICG assisted peeling of the internal limiting membrane may cause retinal damage 显示文摘 | Gandorfer A Haritoglou C Gass CA | 2001 | Am J Ophthalmol2001，132，： | 1 |
| 5 | Effect of calcium dobesilate on occurrence of diabetic macular oedema (CALDIRET study):randomised,double-blind,placebo-controlled,multicentre trial显示文摘 | Haritoglou C Gerss J Sauerland C | | 0，，9672： | 1 |
| 6 | Intravitreal bevacizumab (Avastin) therapy for persistent diffuse diabetic macular edema 显示文摘 | Haritoglou C Kook D Neubauer A | 2006 | Retina2006，26，： | 1 |
| 7 | Epiretinal pathology of diffuse diabetic macular edema associated with vitreomacular traction显示文摘 | Arnd Gandorfer Matthias Rohleder Sabine Grosselfinger Christos Haritoglou Michael Ulbig Anselm Kampik | 2005 | American Journal of Ophthalmology2005，，4： | 1 |
| 8 | Intravitreal bevaeizumab(Avastin) therapy for persistent diffuse diabetic maeular edema显示文摘 | Haritoglou C Kook D Neubauer A | 2006 | Retina2006，26，： | 1 |
| 9 | Five-year fol-low-up of macular hole surgery with peeling of the internal lim-iting membrane:update of a prospective study 显示文摘 | Haritoglou C Reiniger IW Schaumberger M | 2006 | Retina2006，26，： | 1 |
| 10 | Indocya- nine green-assisted peeling of the internal limiting mem- brane in macular hole surgery affects visual outcome: a clinicopathologic correlation显示文摘 | Haritoglou C Gandorfer A Gass C A | 2002 | Am J Ophthalmol2002，134，： | 1 |
| 11 | Macular hole size as a prognostic factor in macular hole surgery显示文摘 | U1Mch S Haritoglou C Gass C | 2002 | Br J Ophthalmol2002，86，： | 1 |
| 12 | 糖尿病视网膜病变中微动脉瘤荧光素渗出与视网膜增厚的关系(英文)显示文摘目的:观察糖尿病视网膜病变患者血管荧光素造影微动脉瘤处渗出与视网膜增厚的关系。方法:选取糖尿病视网膜病变患者24例38眼,首次及末次血管荧光素造影检查确定是否存在微动脉瘤荧光素渗出。根据毛细血管闭塞区的位置选取微动脉瘤荧光素渗出与未渗出各1眼配对进行对比。在微动脉瘤和直径为1mm区域使用光学相干断层成像术(OCT)测量视网膜厚度。结果:微动脉瘤荧光素渗出眼视网膜厚度明显高于未渗出眼(356±69μmvs318±56μm,P<0.001),渗出眼平均增长厚度高于未渗出眼(95%的可信区间为25~51μm,P<0.001).在直径为1mm区域,渗出眼视网膜厚度和平均增长厚度均明显高于未渗出眼(351±67μmvs319±59μm;最小值311±62μmvs284±60μm;最大值389±78μmvs352±66μm)。结论:血管荧光素造影显示微动脉瘤荧光素渗出可以增加视网膜厚度,并运用高分辨率OCT测量。因此,对糖尿病视网膜病变患者早期诊断微动脉瘤荧光素是否渗出可以抑制视网膜增厚。 | Lukas Reznicek Marcus Kernt Christos Haritoglou Michael Ulbig Anselm Kampik Aljoscha S Neubauer | 2011 | 国际眼科杂志2011，11，7： | 1 |
| 13 | Macular hole size as a prognostic factor in macular hole surgery 显示文摘 | Ullrich S Haritoglou C Gass C | 2002 | Br Ophthalmol2002，86，： | 1 |
| 14 | A long-term follow-up after macular hole surgery with internal limiting membrane peeling显示文摘 | Haritoglou C Gass CA Schaumberger M | 2002 | Am J Ophthalmol2002，134，5： | 1 |
| 15 | Macular hole size as a prognostic factor in macular hole surgery 显示文摘 | Ullrich S Haritoglou C Gass C | 2002 | Br J Ophthalmol2002，86，4： | 1 |
| 16 | Functional outcome after trypan blue-assisted vitrectomy for macular pucker:a prospective,randomized,comparative trial显示文摘 | Haritoglou C Eibl K Schaumberger M | 2004 | Am J Ophthalmol2004，138，1： | 1 |
| 17 | Evalua- tion of the internal limiting membrane after conventional peeling during macular hole surgery 显示文摘 | Haritoglou C Schumann R Reiniger I | 2006 | Retina2006，26，： | 1 |
| 18 | Intravitreal bevacizumab (Avastin) therapy for persistent diffuse diabetic macuiar edema显示文摘 | Haritoglou C Kook D Neubauer A Woff A Priglinger S Strauss R | | 0，，09： | 1 |
| 19 | Retinal damage from indocyanine green in exprimental,macular surgery显示文摘 | Gandorfer A Haritoglou C Gandorfer A Kampik A | 2003 | Invest Ophthalmol Vis Sci2003，44，1： | 1 |
| 20 | Macular hole size as aprognostic factor in macular hole surgery 显示文摘 | Ullrich S Haritoglou C Gass C | 2002 | Br J Ophthalmol2002，86，4： | 1 |
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