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| 1 | Recent progress of fully synthetic carbohydrate-based vaccine using TLR agonist as build-in adjuvant显示文摘Fully synthetic vaccine, in which one or multi-molecular antigens are conjugated to a synthetic carrier with well-defined chemical structure, is a new direction to develop carbohydrate-based vaccine against cancer and pathogens. Toll like receptor(TLR) agonists with the ability to stimulate immune response have been widely investigated and been applied as build-in adjuvants to construct fully synthetic vaccines. In particular, remarkable progress has been achieved in recent years in the development of vaccines constructed with the agonists of TLR1/2, TLR2/6 and TLR4 and tumor-associated carbohydrate antigens(TACAs). These di-, tri-or multi-component vaccine candidates showed attractive immunological properties. This review highlights recent advances in developing full synthetic carbohydrate antigen based vaccines, with an emphasis on the structure-activity relationships that provide a primary basis for future vaccine design and immunotherapy developing. | Zhifang Zhou Hart Lin Chen Li Zhimeng Wu | 2018 | Chinese Chemical Letters2018，29，1： | 6 |
| 2 | Weighted Polar Decomposition显示文摘In this paper,a new matrix decomposition called the weighted polar decomposition is considered.Two uniqueness theorems of weighted polar decomposition are presented,and the best approximation property of weighted unitary polar factor and perturbation bounds for weighted polar decomposition are also studied. | YANG Hu LI Hart Yu | 2009 | Journal of Mathematical Research and Exposition2009，29，5： | 5 |
| 3 | ANTI-PLANE ANALYSIS FOR ELLIPTICAL INCLUSION IN MAGNETOELECTROELASTIC MATERIALS显示文摘This paper considers the multi-field coupling in magneroelectroelastic composite materials consisting of the inclusion and the matrix are magnetoelectroelastic materials. The mechanical,electric and magnetic fields around an elliptical cylinder inclusion are formulated by complex potentials. Inside the inclusion,the strain,electric and magnetic fields are found to be uniform and vary with the shape of the ellipse. When the inclusion is reduced to a crack,along the interface,the strain,electric field strength and magnetic field strength equal the corresponding remote ones,which can be used as the boundary condition. Special cases,such as a rigid and permeable inclusion,a soft and impermeable inclusion,a line inclusion and a crack problem are discussed in detail. | Gang Li Baolin Wang Jiecai Hart Shanyi Du | 2009 | Acta Mechanica Solida Sinica2009，22，2： | 3 |
| 4 | 通过地质导向提高产量显示文摘为了延长老油田的寿命,油气公司需要将通常很难勘探和开采的储量作为开发目标。新的定向深探测随钻测井技术有助于地学专家实时确定高阻层边界和流体接触面的位置。采用这些信息优化井眼轨迹,使作业者能够通过提高产量、减少侧钻以及减少井眼失稳问题来获得更大的经济效益。 | Lawrence Chou Qiming Li Alexis Darquin Jean-Michel Denichou Roger Griffiths Nick Hart Alan Mclnally Gerhard Templeton Dzevat Omeragic Ian Tribe Kim Watson Margrethe Wiig | 2007 | 国外测井技术2007，22，3： | 2 |
| 5 | Real time Evolved Gas Analysis by FTIR Method: An Experimental Study of Cellulose Pyrolysis显示文摘 | Li S Lyons Hart J Banyasz J | 2001 | Fuel2001，80，12： | 1 |
| 6 | Dynamics in ratio- dependent predator-prey model with predator harvesting 显示文摘 | Xiao D M Li W X Hart M A | 2006 | Math Anal Appl2006，324，1： | 1 |
| 7 | Cancer-expanded myeloid-de- rived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1 显示文摘 | Li H Hart Y Guo Q | 2009 | J Immunol2009，182，1： | 1 |
| 8 | Microstructure and proper- ties of high chrome steel roller after laser surface melting 显示文摘 | Li M Y Wang Y Hart B | 2009 | Applied Surface Science2009，255，： | 1 |
| 9 | Active Screen Plasma Nitriding of AISI 316 Austenitic Stainless Steel at Different Potentials显示文摘 | Zhao Cheng Wang Liyin Hart Li | 2008 | Surface Engineering2008，24，3： | 1 |
| 10 | Metabolomic analysis reveals the potential metabolites and pathogenesis involved in mulJcerry yellow dwarf disease显示文摘 | Gai Y P Hart X J Li Y Q | 2014 | Plant Cell & Environment2014，37，6： | 1 |
| 11 | Growth and characterization of dumbbell - shaped MgO nanowhiskers 显示文摘 | Chen Yongjun Li Jianbao Hart Yongsheng | 2003 | Ceramics International2003，29，5： | 1 |
| 12 | Optimal guaranteed cost control of uncertain linear system with input constrains 显示文摘 | Y Li Q L Hart M X Sun | 2005 | International Journal of Control Automation and Systems2005，3，3： | 1 |
| 13 | Collision of the North China and Yangtse Blocks and formation of coesite-bearing eclogites: Timing and processes显示文摘 | Li Shuguang Xiao Yilin Lion Deliang Chert Yizhi Ge Ningjie Zhang Zongqing Sun Shen-su Cong Bolin Zhang Ruyuan Hart S R Wang Songshan | 1993 | Chem Geol1993，109，14： | 1 |
| 14 | A Class of Strong Limit Theorems and Moment Generating Function Method显示文摘In virtue of the notion of likelihood ratio and moment generating function,the limit properties of the sequences of absolutely continuous random variables are studied,and a class of strong limit theorems represented by inequalities with random bounds are obtained. | Wen Hart LI Gao Rong LI Nan Bin CAO | 2012 | Journal of Mathematical Research with Applications2012，32，1： | 1 |
| 15 | Interpenetrating polymer networks of bismaleimide and polyether polyurethane- crosslinked epoxy显示文摘 | J L Hart K Y Li | 1998 | J Appl Polym Sci1998，70，： | 1 |
| 16 | Photothermal therapy of cancer cells u- sing novel hollow gold nanoflowers 显示文摘 | Hart J Li J Jia W | 2014 | Int J Nanomedieine2014，169，： | 1 |
| 17 | Comparison of hemodynamics after combined spinal - epidural anesthesia between decubitus and sitting positions in aged patients undergoing total hip replacement 显示文摘 | Hart G Zhao GY Li L | 2014 | Pharmacology2014，93，34： | 1 |
| 18 | Seronegative myasthenia gravis: evidence for plasma factor(s) interfering with acetylcholine receptor function显示文摘 | Vincent A Li Z Hart A | 1993 | Ann NY Acad Sci1993，681，： | 1 |
| 19 | Coupled aerodynamic/ structural optimization of a subsonic transport wing using a surrogate model显示文摘 | Zhang Keshi Hart Zhonghua Li Weiji | 2008 | Joumal of Aircraft2008，45，6： | 1 |
| 20 | Mechanisms of insulin resistance in experimental hyper-insulinemic dogs显示文摘 | Miles P D Li S Hart M | 1998 | J Clin Invest1998，101，1： | 1 |
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