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| 1 | 血脂、脂蛋白和载脂蛋白作为心肌梗死风险标志物(INTER-HEART研究):在52个国家进行的一项病例对照研究显示文摘背景载脂蛋白作为冠心痛的标志物是否优于血脂和脂蛋白,目前存在广泛争议。本研究旨在对载脂蛋白和胆固醇作为急性心肌梗死风险指标进行比较.
方法在52个国家的12461例急性心肌梗死患者和14637例年龄(±5岁)、性别匹配的对照者中进行了一项有关急性心肌梗死的大型、标准化病例对照研究。获得了9345例急性心肌梗死患者和12120例对照者的非空腹血液样本。测定了血脂、脂蛋白和载脂蛋白浓度,并计算了胆固醇和栽脂蛋白比值通过比较五分位数的上四位与最低位,计算每一总体测值和每一种族组的优势比(0R)及其95%CI以及人群归因危险度(PAR)。
结果载脂蛋白B100(ApoB)/载脂蛋白A1(ApoA1)比值的PAR最高(54%),其每一标准差差别的OR最高(1.59,95%CI1.53~1.64)。LDL胆固醇/HDL-胆固醇比值的PAR为37%;总胆固醇/HDL-胆固醇的PAR为32%,其显著低于ApoB/A1比值的PAR(P〈0.0001)。这些结果在所有种族组、男女两性组及所有年龄组均一致。
结论在所有种族组、男女两性组及所有年龄组,非空腹ApoB/A1比值在评估急性心肌梗死风险方面优于任何胆固醇比值,其应当被引入全世界的临床实践中。 | Matthew J McQueen Steven Hawken Xingyu Wang Stephanie Ounpuu Allan Sniderman Jeffrey Probstfield Krisela Steyn John E Sanderson Mahammad Hasani Emilia Volkova Khawar Kazmi Salim Yusuf 郭战宏(译) | 2008 | 世界临床医学2008，2，6： | 3 |
| 2 | Regional Lung Clear- ance during Cough and Forced Expiration Technique (FET): Effects of Flow and Viscoelasticity显示文摘 | Hasani A Pavia D Agnew J E | 1994 | Thorax1994，49，6： | 1 |
| 3 | The effect of low-dose remifentanil on the hemodynamic responses of endotracheal extubation显示文摘 | Mahoori A Noroozinia H Hasani E | 2014 | Acta Med Iran2014，52，11： | 1 |
| 4 | Association between HLA-G 3' UTR 14-bp ins/del polymorphism and susceptibility to breast cancer 显示文摘 | Eskandari-Nasab E Hashemi M Hasani SS | 2013 | Cancer Biomark2013，13，4： | 1 |
| 5 | A functional polymorphism in the miR-146a gene is associated with the risk of childhood acute lymphoblastic leukemia:a preliminary report显示文摘 | Hasani SS Hashemi M Eskandari-Nasab E | 2014 | Tumor Biol2014，35，： | 1 |
| 6 | Relationship of Serum Cystatin C to Peritoneal and Renal Clearance Measures in Peritoneal Dialysis:a Cross-sectional Study显示文摘 | Delaney M P Stevens P E Al Hasani M | 2008 | Am J Kidney Dis2008，51，2： | 1 |
| 7 | Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study显示文摘 | Matthew J McQueen Steven Hawken Xingyu Wang Stephanie Ounpuu Allan Sniderman Jeffrey Probstfield Krisela Steyn John E Sanderson Mohammad Hasani Emilia Volkova Khawar Kazmi Salim Yusuf | 2008 | The Lancet2008，，9634： | 1 |
| 8 | The effect of low dose remifentanil on the hemodynamic responses of endotracheal extubation显示文摘 | Mahoori A Noroozinia H Hasani E | 2014 | Acta Med Iran2014，5201，： | 1 |
| 9 | Reactive oxygen species, total antioxidant concentration of seminal plasma and their effect on sperm parameters and outcome of IVF/ICSI patients 显示文摘 | Hammadeh M E Ai Hasani S Rosenbaum P | 2008 | Arch Gynecol Obstet2008，277，6： | 1 |
| 10 | Robust closed-loop supply chain network design for perishable goods in agile manufac- turing under uncertainty 显示文摘 | HASANI A ZEGORDI S H NIKBAKHSH E | 2012 | International Journal of Production Re- search2012，50，16： | 1 |
| 11 | Cationic surface functionalization of cellulose nanocrystals显示文摘 | Hasani M Cranston E D Westman G | 2008 | Soft Matter2008，4，11： | 1 |
| 12 | Cationic surface functionalization of cellulose nanocrystals显示文摘 | HASANI M CRANSTON E D WESTMANA G | | 0，，11： | 1 |
| 13 | Survival of block and fascial-wrapped diced cartilage grafts: an experimental study in rab- bits显示文摘 | Fatemi M I Hasani M E Rahimian S | 2012 | Ann Plast Surg2012，69，3： | 1 |
| 14 | The effect of low-dose remifentanil on the hemodynamic responses of endotracheal extubation 显示文摘 | Mahoori A Noroozinia H Hasani E | 2014 | Acta Med Iran2014，52，11： | 1 |
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